Entrez Gene

Basic Information
Gene ID	653604
Name	HIST2H3D
Synonymous	histone cluster 2, H3d;HIST2H3D;histone cluster 2, H3d
Definition	histone 2, H3d\|histone H3.2
Position	1q21.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.355A>G; p.T119A; 1:149813327-149813327	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.50C>G; p.P17R; 1:149813632-149813632	urinary_tract; bladder	carcinoma	Substitution - Missense
c.406G>A; p.A136T; 1:149813276-149813276	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.23C>T; p.A8V; 1:149813659-149813659	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.346A>T; p.K116*; 1:149813336-149813336	skin	malignant_melanoma	Substitution - Nonsense
c.151G>A; p.E51K; 1:149813531-149813531	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.25C>T; p.R9C; 1:149813657-149813657	thyroid	carcinoma	Substitution - Missense
c.107T>G; p.V36G; 1:149813575-149813575	urinary_tract; bladder	carcinoma	Substitution - Missense
c.107T>G; p.V36G; 1:149813575-149813575	urinary_tract; bladder	carcinoma	Substitution - Missense
c.107T>G; p.V36G; 1:149813575-149813575	urinary_tract; bladder	carcinoma	Substitution - Missense
c.107T>G; p.V36G; 1:149813575-149813575	urinary_tract; bladder	carcinoma	Substitution - Missense
c.107T>G; p.V36G; 1:149813575-149813575	urinary_tract; bladder	carcinoma	Substitution - Missense
c.107T>G; p.V36G; 1:149813575-149813575	urinary_tract; bladder	carcinoma	Substitution - Missense
c.264G>A; p.S88S; 1:149813418-149813418	skin	malignant_melanoma	Substitution - coding silent
c.264G>A; p.S88S; 1:149813418-149813418	breast	carcinoma	Substitution - coding silent
c.6C>G; p.A2A; 1:149813676-149813676	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.360C>T; p.I120I; 1:149813322-149813322	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.319G>C; p.D107H; 1:149813363-149813363	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.292G>C; p.E98Q; 1:149813390-149813390	breast	carcinoma	Substitution - Missense
c.370G>T; p.D124Y; 1:149813312-149813312	breast	carcinoma	Substitution - Missense
c.69C>T; p.T23T; 1:149813613-149813613	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.333C>T; p.C111C; 1:149813349-149813349	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.61C>T; p.L21L; 1:149813621-149813621	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.25C>A; p.R9S; 1:149813657-149813657	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.404G>A; p.R135Q; 1:149813278-149813278	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.127C>T; p.R43W; 1:149813555-149813555	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.15G>C; p.K5N; 1:149813667-149813667	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.369G>T; p.K123N; 1:149813313-149813313	breast	carcinoma	Substitution - Missense
c.316G>A; p.E106K; 1:149813366-149813366	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>G; p.H40Q; 1:149813562-149813562	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.222G>C; p.E74D; 1:149813460-149813460	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.24C>T; p.A8A; 1:149813658-149813658	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.11C>G; p.T4S; 1:149813671-149813671	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.82A>T; p.K28*; 1:149813600-149813600	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.388C>T; p.R130C; 1:149813294-149813294	breast	carcinoma	Substitution - Missense
c.261C>A; p.S87R; 1:149813421-149813421	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.261C>A; p.S87R; 1:149813421-149813421	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.261C>A; p.S87R; 1:149813421-149813421	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.261C>A; p.S87R; 1:149813421-149813421	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.32C>T; p.S11L; 1:149813650-149813650	breast	carcinoma	Substitution - Missense
c.32C>T; p.S11L; 1:149813650-149813650	urinary_tract; bladder	carcinoma	Substitution - Missense
c.381G>T; p.L127F; 1:149813301-149813301	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.166C>T; p.Q56*; 1:149813516-149813516	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense

COSMIC somatic mutation [Top]