Entrez Gene

Basic Information
Gene ID	64682
Name	ANAPC1
Synonymous	anaphase promoting complex subunit 1;ANAPC1;anaphase promoting complex subunit 1
Definition	anaphase-promoting complex 1 (meiotic checkpoint regulator)\|anaphase-promoting complex subunit 1\|cyclosome subunit 1\|mitotic checkpoint regulator\|testis-specific gene 24 protein
Position	2q12.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1673C>T; p.P558L; 2:111847843-111847843	skin	malignant_melanoma	Substitution - Missense
c.5308C>A; p.L1770I; 2:111778752-111778752	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1580G>A; p.R527Q; 2:111850846-111850846	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1580G>A; p.R527Q; 2:111850846-111850846	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1633C>T; p.L545F; 2:111850793-111850793	skin	malignant_melanoma	Substitution - Missense
c.1580G>A; p.R527Q; 2:111850846-111850846	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1377G>A; p.E459E; 2:111856868-111856868	skin	malignant_melanoma	Substitution - coding silent
c.3641C>T; p.A1214V; 2:111809138-111809138	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3832+7G>A; p.?; 2:111808940-111808940	stomach	carcinoma; adenocarcinoma	Unknown
c.3832+7G>A; p.?; 2:111808940-111808940	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.3832+7G>A; p.?; 2:111808940-111808940	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.941C>T; p.P314L; 2:111863786-111863786	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1115C>A; p.S372*; 2:111862536-111862536	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1115C>A; p.S372*; 2:111862536-111862536	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3640G>T; p.A1214S; 2:111809139-111809139	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4798C>T; p.R1600W; 2:111788235-111788235	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.5091A>G; p.L1697L; 2:111782480-111782480	pancreas	carcinoma	Substitution - coding silent
c.4984C>A; p.L1662I; 2:111784334-111784334	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4984C>A; p.L1662I; 2:111784334-111784334	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1560G>T; p.T520T; 2:111850866-111850866	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2765C>T; p.S922F; 2:111825013-111825013	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1085C>T; p.S362F; 2:111862566-111862566	skin	malignant_melanoma	Substitution - Missense
c.5308C>T; p.L1770F; 2:111778752-111778752	skin	malignant_melanoma	Substitution - Missense
c.5176_5177AG>TC; p.R1726S; 2:111782394-111782395	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3278A>C; p.H1093P; 2:111818887-111818887	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5302C>A; p.L1768M; 2:111778758-111778758	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1135A>T; p.K379*; 2:111862516-111862516	skin	malignant_melanoma	Substitution - Nonsense
c.5184T>A; p.S1728S; 2:111782387-111782387	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1691C>T; p.S564L; 2:111847825-111847825	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5203-3delT; p.?; 2:111780388-111780388	stomach	adenocarcinoma	Unknown
c.1894G>T; p.E632*; 2:111843558-111843558	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.572G>A; p.R191Q; 2:111872669-111872669	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.664C>G; p.P222A; 2:111868044-111868044	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.664C>G; p.P222A; 2:111868044-111868044	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.664C>G; p.P222A; 2:111868044-111868044	prostate	carcinoma	Substitution - Missense
c.4341G>A; p.P1447P; 2:111794850-111794850	breast	carcinoma	Substitution - coding silent
c.1737G>A; p.Q579Q; 2:111847779-111847779	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2076G>A; p.A692A; 2:111838477-111838477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.530T>C; p.V177A; 2:111872711-111872711	skin	malignant_melanoma	Substitution - Missense
c.1064C>T; p.S355F; 2:111862587-111862587	skin	malignant_melanoma	Substitution - Missense
c.1549C>A; p.P517T; 2:111850877-111850877	breast	carcinoma	Substitution - Missense
c.2804C>G; p.T935S; 2:111824974-111824974	pancreas	carcinoma	Substitution - Missense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	thyroid	other; neoplasm	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	thyroid	other; neoplasm	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1393C>T; p.Q465*; 2:111856852-111856852	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4958C>T; p.A1653V; 2:111784360-111784360	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3620G>A; p.G1207E; 2:111809159-111809159	breast	carcinoma	Substitution - Missense
c.4978C>T; p.L1660F; 2:111784340-111784340	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1286A>C; p.K429T; 2:111858378-111858378	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3716C>T; p.T1239M; 2:111809063-111809063	thyroid	carcinoma; anaplastic_carcinoma	Substitution - Missense
c.5064-7C>A; p.?; 2:111782514-111782514	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1308A>G; p.L436L; 2:111858356-111858356	thyroid	other; neoplasm	Substitution - coding silent
c.1308A>G; p.L436L; 2:111858356-111858356	thyroid	other; neoplasm	Substitution - coding silent
c.1308A>G; p.L436L; 2:111858356-111858356	liver	carcinoma	Substitution - coding silent
c.1308A>G; p.L436L; 2:111858356-111858356	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1308A>G; p.L436L; 2:111858356-111858356	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - coding silent
c.5667C>T; p.L1889L; 2:111772393-111772393	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.982C>T; p.Q328*; 2:111863745-111863745	skin; arm	malignant_melanoma	Substitution - Nonsense
c.1308A>G; p.L436L; 2:111858356-111858356	liver	carcinoma	Substitution - coding silent
c.1396C>T; p.L466F; 2:111856849-111856849	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1358G>T; p.R453L; 2:111858306-111858306	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1040T>C; p.M347T; 2:111863687-111863687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2368C>T; p.L790F; 2:111834620-111834620	skin; mucosal	malignant_melanoma	Substitution - Missense
c.2282C>T; p.A761V; 2:111834706-111834706	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2612G>A; p.R871K; 2:111831299-111831299	breast	carcinoma	Substitution - Missense
c.1020C>T; p.R340R; 2:111863707-111863707	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2537A>C; p.Q846P; 2:111831374-111831374	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1852+4C>T; p.?; 2:111847134-111847134	pancreas	carcinoma	Unknown
c.5130A>G; p.E1710E; 2:111782441-111782441	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1628A>C; p.K543T; 2:111850798-111850798	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2300A>G; p.H767R; 2:111834688-111834688	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1596A>T; p.L532L; 2:111850830-111850830	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.4981C>T; p.H1661Y; 2:111784337-111784337	skin	malignant_melanoma	Substitution - Missense
c.2160G>A; p.E720E; 2:111834828-111834828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5355G>A; p.E1785E; 2:111778705-111778705	skin	malignant_melanoma	Substitution - coding silent
c.1645G>C; p.D549H; 2:111850781-111850781	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4774T>C; p.F1592L; 2:111788259-111788259	skin	malignant_melanoma	Substitution - Missense
c.4217T>C; p.L1406P; 2:111802432-111802432	breast	carcinoma	Substitution - Missense
c.1791G>A; p.L597L; 2:111847725-111847725	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1791G>A; p.L597L; 2:111847725-111847725	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.4972C>T; p.P1658S; 2:111784346-111784346	skin	malignant_melanoma	Substitution - Missense
c.4972C>T; p.P1658S; 2:111784346-111784346	skin	malignant_melanoma	Substitution - Missense
c.1353G>C; p.Q451H; 2:111858311-111858311	thyroid	other; neoplasm	Substitution - Missense
c.1353G>C; p.Q451H; 2:111858311-111858311	thyroid	other; neoplasm	Substitution - Missense
c.1844C>G; p.S615C; 2:111847146-111847146	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1388A>C; p.K463T; 2:111856857-111856857	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1353G>C; p.Q451H; 2:111858311-111858311	thyroid	other; neoplasm	Substitution - Missense
c.3670A>G; p.I1224V; 2:111809109-111809109	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1353G>C; p.Q451H; 2:111858311-111858311	thyroid	other; neoplasm	Substitution - Missense
c.2731G>A; p.E911K; 2:111825141-111825141	thyroid	carcinoma; anaplastic_carcinoma	Substitution - Missense
c.3780A>G; p.V1260V; 2:111808999-111808999	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.869delG; p.G290fs*26; 2:111863858-111863858	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1609A>G; p.T537A; 2:111850817-111850817	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4918G>A; p.G1640S; 2:111784400-111784400	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	skin	malignant_melanoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5112T>G; p.G1704G; 2:111782459-111782459	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1609A>G; p.T537A; 2:111850817-111850817	NS	malignant_melanoma	Substitution - Missense
c.4918G>A; p.G1640S; 2:111784400-111784400	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1609A>G; p.T537A; 2:111850817-111850817	skin	malignant_melanoma	Substitution - Missense
c.1288G>C; p.V430L; 2:111858376-111858376	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2292C>T; p.F764F; 2:111834696-111834696	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1456G>C; p.D486H; 2:111856673-111856673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.940C>T; p.P314S; 2:111863787-111863787	skin	malignant_melanoma	Substitution - Missense
c.2729A>G; p.Q910R; 2:111825143-111825143	pancreas	carcinoma	Substitution - Missense
c.2729A>G; p.Q910R; 2:111825143-111825143	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1995G>A; p.M665I; 2:111843457-111843457	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1526T>C; p.V509A; 2:111850900-111850900	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1995G>A; p.M665I; 2:111843457-111843457	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1545A>C; p.P515P; 2:111850881-111850881	skin	malignant_melanoma	Substitution - coding silent
c.2705C>T; p.A902V; 2:111825167-111825167	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.688C>A; p.L230I; 2:111864949-111864949	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4747G>A; p.A1583T; 2:111788286-111788286	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4747G>A; p.A1583T; 2:111788286-111788286	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.428-3C>T; p.?; 2:111873411-111873411	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.4468A>G; p.K1490E; 2:111794128-111794128	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.415G>C; p.E139Q; 2:111873625-111873625	breast	carcinoma	Substitution - Missense
c.2314G>A; p.E772K; 2:111834674-111834674	skin	malignant_melanoma	Substitution - Missense
c.3172A>C; p.S1058R; 2:111821273-111821273	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4676A>G; p.H1559R; 2:111792398-111792398	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4736C>A; p.S1579Y; 2:111788297-111788297	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.988C>T; p.R330C; 2:111863739-111863739	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2131C>A; p.L711I; 2:111834857-111834857	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4753C>A; p.L1585I; 2:111788280-111788280	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4551C>T; p.S1517S; 2:111792523-111792523	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.5178G>A; p.R1726R; 2:111782393-111782393	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1450-2_1450-1insA; p.?; 2:111856680-111856681	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.1859C>T; p.T620M; 2:111843593-111843593	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5782T>G; p.L1928V; 2:111769344-111769344	breast	carcinoma	Substitution - Missense
c.1109A>G; p.N370S; 2:111862542-111862542	skin	malignant_melanoma	Substitution - Missense
c.1030A>T; p.I344F; 2:111863697-111863697	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4649T>A; p.M1550K; 2:111792425-111792425	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1952C>G; p.P651R; 2:111843500-111843500	breast	carcinoma; lobular_carcinoma	Substitution - Missense
c.6G>A; p.S2S; 2:111880820-111880820	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4731A>C; p.S1577S; 2:111788302-111788302	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6G>A; p.S2S; 2:111880820-111880820	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2654A>G; p.E885G; 2:111825827-111825827	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.5202G>A; p.K1734K; 2:111782369-111782369	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.655G>A; p.E219K; 2:111868053-111868053	breast	carcinoma	Substitution - Missense
c.3677G>A; p.R1226Q; 2:111809102-111809102	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.937T>C; p.S313P; 2:111863790-111863790	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4501G>T; p.A1501S; 2:111794095-111794095	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.993A>G; p.S331S; 2:111863734-111863734	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4500C>T; p.S1500S; 2:111794096-111794096	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.4500C>T; p.S1500S; 2:111794096-111794096	thyroid	other; neoplasm	Substitution - coding silent
c.4500C>T; p.S1500S; 2:111794096-111794096	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4500C>T; p.S1500S; 2:111794096-111794096	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.5608G>T; p.A1870S; 2:111772452-111772452	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.529-10delT; p.?; 2:111872722-111872722	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.5070C>T; p.I1690I; 2:111782501-111782501	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1702G>A; p.D568N; 2:111847814-111847814	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2709C>A; p.P903P; 2:111825163-111825163	prostate	adenoma	Substitution - coding silent
c.1022C>T; p.S341L; 2:111863705-111863705	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1358+2T>C; p.?; 2:111858304-111858304	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.656A>G; p.E219G; 2:111868052-111868052	skin	malignant_melanoma	Substitution - Missense
c.2571G>T; p.M857I; 2:111831340-111831340	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1680G>T; p.L560L; 2:111847836-111847836	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.4306G>A; p.E1436K; 2:111794885-111794885	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.5355G>T; p.E1785D; 2:111778705-111778705	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3680T>A; p.L1227H; 2:111809099-111809099	skin	malignant_melanoma	Substitution - Missense
c.1406G>A; p.G469D; 2:111856839-111856839	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5705C>T; p.P1902L; 2:111772355-111772355	skin	malignant_melanoma	Substitution - Missense
c.1524G>A; p.K508K; 2:111850902-111850902	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1357C>T; p.R453C; 2:111858307-111858307	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4770G>A; p.P1590P; 2:111788263-111788263	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2252C>T; p.S751F; 2:111834736-111834736	skin; extremity	malignant_melanoma	Substitution - Missense
c.2365C>T; p.L789F; 2:111834623-111834623	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2713A>C; p.K905Q; 2:111825159-111825159	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2365C>T; p.L789F; 2:111834623-111834623	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1805G>A; p.G602D; 2:111847185-111847185	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.732G>T; p.M244I; 2:111864905-111864905	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4143-7C>T; p.?; 2:111802513-111802513	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.2576C>T; p.P859L; 2:111831335-111831335	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.1199C>T; p.T400M; 2:111862452-111862452	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3186C>T; p.F1062F; 2:111821259-111821259	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4169C>A; p.P1390H; 2:111802480-111802480	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.5177G>C; p.R1726T; 2:111782394-111782394	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2781T>G; p.A927A; 2:111824997-111824997	skin	malignant_melanoma	Substitution - coding silent
c.4406G>T; p.C1469F; 2:111794291-111794291	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1171T>G; p.S391A; 2:111862480-111862480	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2021G>A; p.R674H; 2:111843431-111843431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2122G>A; p.E708K; 2:111834866-111834866	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4537G>T; p.E1513*; 2:111792537-111792537	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.840T>A; p.N280K; 2:111863887-111863887	skin	malignant_melanoma	Substitution - Missense
c.1431G>A; p.K477K; 2:111856814-111856814	skin	malignant_melanoma	Substitution - coding silent
c.5304G>T; p.L1768L; 2:111778756-111778756	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4332C>T; p.I1444I; 2:111794859-111794859	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1450-3_1450-2insT; p.?; 2:111856681-111856682	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1358+8T>C; p.?; 2:111858298-111858298	stomach	adenocarcinoma	Unknown
c.3227G>A; p.R1076Q; 2:111818938-111818938	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1174A>G; p.N392D; 2:111862477-111862477	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.5085_5086GG>TT; p.V1696F; 2:111782485-111782486	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.5310C>G; p.L1770L; 2:111778750-111778750	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.675T>C; p.C225C; 2:111868033-111868033	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.631T>G; p.F211V; 2:111868077-111868077	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1358+8T>G; p.?; 2:111858298-111858298	liver	carcinoma	Unknown
c.3123_3124delTC; p.Q1042fs*17; 2:111821321-111821322	oesophagus	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.670G>C; p.V224L; 2:111868038-111868038	pancreas	other; adenoma	Substitution - Missense
c.1870G>A; p.A624T; 2:111843582-111843582	NS	malignant_melanoma	Substitution - Missense
c.5373C>A; p.I1791I; 2:111778687-111778687	thyroid	other; neoplasm	Substitution - coding silent
c.5373C>A; p.I1791I; 2:111778687-111778687	thyroid	other; neoplasm	Substitution - coding silent
c.5373C>A; p.I1791I; 2:111778687-111778687	thyroid	other; neoplasm	Substitution - coding silent
c.2346A>C; p.G782G; 2:111834642-111834642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.548C>G; p.T183S; 2:111872693-111872693	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2207C>T; p.S736L; 2:111834781-111834781	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1384G>A; p.D462N; 2:111856861-111856861	skin	malignant_melanoma	Substitution - Missense
c.1247C>T; p.T416M; 2:111862404-111862404	skin; extremity	malignant_melanoma	Substitution - Missense
c.1247C>T; p.T416M; 2:111862404-111862404	breast	carcinoma	Substitution - Missense
c.1612C>G; p.P538A; 2:111850814-111850814	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1247C>T; p.T416M; 2:111862404-111862404	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4953G>T; p.L1651F; 2:111784365-111784365	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1247C>T; p.T416M; 2:111862404-111862404	breast	carcinoma	Substitution - Missense
c.42A>C; p.A14A; 2:111880784-111880784	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.4739C>T; p.S1580F; 2:111788294-111788294	NS	malignant_melanoma	Substitution - Missense
c.4755C>G; p.L1585L; 2:111788278-111788278	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4739C>T; p.S1580F; 2:111788294-111788294	NS	malignant_melanoma	Substitution - Missense
c.2672A>C; p.E891A; 2:111825809-111825809	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2511delT; p.F837fs*12; 2:111831400-111831400	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2143T>C; p.Y715H; 2:111834845-111834845	skin	malignant_melanoma	Substitution - Missense
c.1412T>C; p.V471A; 2:111856833-111856833	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2000T>C; p.M667T; 2:111843452-111843452	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4799G>A; p.R1600Q; 2:111788234-111788234	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4953G>C; p.L1651F; 2:111784365-111784365	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2205T>C; p.A735A; 2:111834783-111834783	breast	carcinoma	Substitution - coding silent
c.5034A>C; p.I1678I; 2:111783926-111783926	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1599T>C; p.D533D; 2:111850827-111850827	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.4655A>G; p.Y1552C; 2:111792419-111792419	breast	carcinoma	Substitution - Missense
c.4589C>T; p.S1530L; 2:111792485-111792485	urinary_tract; bladder	carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]