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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6125

Name

RPL5

Synonymous

ribosomal protein L5;RPL5;ribosomal protein L5

Definition

60S ribosomal protein L5|protein phosphatase 1, regulatory subunit 135

Position

1p22.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.535C>T; p.R179*; 1:92837463-92837463

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Nonsense

c.608A>T; p.N203I; 1:92837536-92837536

 livercarcinomaSubstitution - Missense

c.619T>C; p.Y207H; 1:92837547-92837547

 oesophaguscarcinomaSubstitution - Missense

c.619T>C; p.Y207H; 1:92837547-92837547

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.666G>A; p.Q222Q; 1:92837594-92837594

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.623T>C; p.M208T; 1:92837551-92837551

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.325-1G>C; p.?; 1:92836189-92836189

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.634_634A>GC; p.M212fs*5; 1:92837562-92837562

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaComplex - frameshift

c.290C>G; p.A97G; 1:92834879-92834879

 breastcarcinomaSubstitution - Missense

c.119A>C; p.D40A; 1:92833590-92833590

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.518T>C; p.I173T; 1:92836383-92836383

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.295T>C; p.Y99H; 1:92834884-92834884

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.166_169delACAA; p.N57fs*12; 1:92833637-92833640

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.166_169delACAA; p.N57fs*12; 1:92833637-92833640

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.166_169delACAA; p.N57fs*12; 1:92833637-92833640

 breastcarcinomaDeletion - Frameshift

c.229G>A; p.A77T; 1:92834818-92834818

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.774G>T; p.K258N; 1:92840619-92840619

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.774G>T; p.K258N; 1:92840619-92840619

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.13A>T; p.K5*; 1:92833398-92833398

 skinmalignant_melanomaSubstitution - Nonsense

c.189+1G>C; p.?; 1:92833661-92833661

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.104_116del13; p.R35fs*13; 1:92833575-92833587

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaDeletion - Frameshift

c.177_183delTATCATT; p.I60fs*8; 1:92833648-92833654

 breastcarcinomaDeletion - Frameshift

c.795-1G>C; p.?; 1:92841765-92841765

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.877C>T; p.R293W; 1:92841848-92841848

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.461C>T; p.T154I; 1:92836326-92836326

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.706-1G>T; p.?; 1:92840550-92840550

 lung; right_lower_lobecarcinoma; adenocarcinomaUnknown

c.748A>C; p.N250H; 1:92840593-92840593

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.439G>C; p.D147H; 1:92836304-92836304

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.48C>A; p.Y16*; 1:92833433-92833433

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Nonsense

c.779A>G; p.E260G; 1:92840624-92840624

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.330C>G; p.L110L; 1:92836195-92836195

 breastcarcinomaSubstitution - coding silent

c.178A>G; p.I60V; 1:92833649-92833649

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.7T>C; p.F3L; 1:92833392-92833392

 skinmalignant_melanomaSubstitution - Missense

c.691G>A; p.V231I; 1:92837619-92837619

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.554C>T; p.S185F; 1:92837482-92837482

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.212G>A; p.G71E; 1:92834801-92834801

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.742C>T; p.R248*; 1:92840587-92840587

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Nonsense

c.269T>C; p.V90A; 1:92834858-92834858

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.529A>G; p.T177A; 1:92837457-92837457

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.527delG; p.S176fs*36; 1:92836392-92836392

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.132C>A; p.Y44*; 1:92833603-92833603

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.89A>T; p.Y30F; 1:92833560-92833560

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.21T>C; p.V7V; 1:92833406-92833406

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.48C>T; p.Y16Y; 1:92833433-92833433

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.11_12insTA; p.K5fs*15; 1:92833396-92833397

 lungcarcinoma; adenocarcinomaInsertion - Frameshift

c.13delA; p.V6fs*13; 1:92833398-92833398

 central_nervous_system; brainglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.527G>A; p.S176N; 1:92836392-92836392

 skinmalignant_melanomaSubstitution - Missense

c.3+1G>A; p.?; 1:92832118-92832118

 lungcarcinoma; adenocarcinomaUnknown

c.190-1G>A; p.?; 1:92834778-92834778

 urinary_tract; bladdercarcinomaUnknown

c.541C>A; p.P181T; 1:92837469-92837469

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.280A>G; p.N94D; 1:92834869-92834869

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.626G>A; p.R209H; 1:92837554-92837554

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.173G>C; p.R58T; 1:92833644-92833644

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.364C>G; p.Q122E; 1:92836229-92836229

 livercarcinomaSubstitution - Missense

c.160C>T; p.R54C; 1:92833631-92833631

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.160C>T; p.R54C; 1:92833631-92833631

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.188A>G; p.Q63R; 1:92833659-92833659

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.695C>A; p.T232N; 1:92837623-92837623

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.506G>T; p.G169V; 1:92836371-92836371

 skinmalignant_melanomaSubstitution - Missense

c.362G>T; p.G121V; 1:92836227-92836227

 prostatecarcinomaSubstitution - Missense

c.747G>T; p.E249D; 1:92840592-92840592

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.747G>T; p.E249D; 1:92840592-92840592

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.743G>A; p.R248Q; 1:92840588-92840588

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.712G>T; p.E238*; 1:92840557-92840557

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.244G>A; p.E82K; 1:92834833-92834833

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.244G>A; p.E82K; 1:92834833-92834833

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemiaSubstitution - Missense

c.244G>A; p.E82K; 1:92834833-92834833

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.244G>A; p.E82K; 1:92834833-92834833

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.244G>A; p.E82K; 1:92834833-92834833

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.172_173delAG; p.D59fs*53; 1:92833643-92833644

 central_nervous_system; brainglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.391A>G; p.N131D; 1:92836256-92836256

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.397G>C; p.E133Q; 1:92836262-92836262

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.443C>G; p.A148G; 1:92836308-92836308

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.150G>C; p.R50S; 1:92833621-92833621

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.374T>C; p.V125A; 1:92836239-92836239

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.374T>C; p.V125A; 1:92836239-92836239

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.803G>A; p.R268H; 1:92841774-92841774

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.614C>T; p.A205V; 1:92837542-92837542

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.175_176delGA; p.D59fs*53; 1:92833646-92833647

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaDeletion - Frameshift

c.676T>C; p.Y226H; 1:92837604-92837604

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.676T>C; p.Y226H; 1:92837604-92837604

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

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