Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5970

Name

RELA

Synonymous

v-rel avian reticuloendotheliosis viral oncogene homolog A;RELA;v-rel avian reticuloendotheliosis viral oncogene homolog A

Definition

NF-kappa-B p65delta3|nuclear factor NF-kappa-B p65 subunit|nuclear factor of kappa light polypeptide gene enhancer in B-cells 3|transcription factor p65|v-rel reticuloendotheliosis viral oncogene homolog A

Position

11q13

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.771C>T; p.Y257Y; 11:65658393-65658393

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.380A>G; p.E127G; 11:65660171-65660171

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.380A>G; p.E127G; 11:65660171-65660171

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.957C>T; p.S319S; 11:65655856-65655856

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.957C>T; p.S319S; 11:65655856-65655856

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.1459delC; p.H487fs*7; 11:65654575-65654575

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1459delC; p.H487fs*7; 11:65654575-65654575

 stomachadenocarcinomaDeletion - Frameshift

c.497G>T; p.R166L; 11:65659728-65659728

 skinmalignant_melanomaSubstitution - Missense

c.497G>T; p.R166L; 11:65659728-65659728

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1643A>C; p.Q548P; 11:65654391-65654391

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.719C>T; p.S240L; 11:65658445-65658445

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1451T>C; p.V484A; 11:65654583-65654583

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.129G>A; p.A43A; 11:65661994-65661994

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.164C>G; p.T55S; 11:65661959-65661959

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1405G>A; p.V469I; 11:65654629-65654629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.297C>A; p.F99L; 11:65661725-65661725

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.446G>A; p.R149H; 11:65659779-65659779

 skinmalignant_melanomaSubstitution - Missense

c.558T>A; p.N186K; 11:65659667-65659667

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.241C>T; p.P81S; 11:65661781-65661781

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.877+2T>G; p.?; 11:65658285-65658285

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.1044C>A; p.P348P; 11:65654990-65654990

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.496C>T; p.R166W; 11:65659729-65659729

 breastcarcinomaSubstitution - Missense

c.1177C>T; p.P393S; 11:65654857-65654857

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.631G>A; p.E211K; 11:65658751-65658751

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1017T>C; p.A339A; 11:65655704-65655704

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.985C>T; p.R329*; 11:65655736-65655736

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.159T>C; p.D53D; 11:65661964-65661964

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.985C>T; p.R329*; 11:65655736-65655736

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.415_417delAAC; p.N139delN; 11:65660134-65660136

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.1505G>C; p.R502P; 11:65654529-65654529

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.237G>A; p.K79K; 11:65661785-65661785

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.741delA; p.V248fs*66; 11:65658423-65658423

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.890G>A; p.R297Q; 11:65655923-65655923

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.799C>T; p.R267C; 11:65658365-65658365

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.394C>T; p.Q132*; 11:65660157-65660157

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.622G>A; p.G208S; 11:65658760-65658760

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.767C>T; p.P256L; 11:65658397-65658397

 skinmalignant_melanomaSubstitution - Missense

c.1285A>C; p.T429P; 11:65654749-65654749

 breastcarcinomaSubstitution - Missense

c.773C>T; p.A258V; 11:65658391-65658391

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.825T>A; p.P275P; 11:65658339-65658339

 livercarcinomaSubstitution - coding silent

c.756_757CC>TT; p.R253W; 11:65658407-65658408

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.825T>A; p.P275P; 11:65658339-65658339

 livercarcinomaSubstitution - coding silent

c.520C>T; p.R174C; 11:65659705-65659705

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.979C>T; p.P327S; 11:65655742-65655742

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.165C>G; p.T55T; 11:65661958-65661958

 bone; fibulaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.506C>G; p.S169*; 11:65659719-65659719

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.684C>T; p.F228F; 11:65658480-65658480

 skinmalignant_melanomaSubstitution - coding silent

c.988C>T; p.R330C; 11:65655733-65655733

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.821G>A; p.R274Q; 11:65658343-65658343

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.115G>A; p.E39K; 11:65662008-65662008

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.559C>T; p.R187C; 11:65659666-65659666

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1148C>T; p.P383L; 11:65654886-65654886

 skinmalignant_melanomaSubstitution - Missense

c.560-2A>G; p.?; 11:65658824-65658824

 stomachcarcinoma; adenocarcinomaUnknown

c.1305G>A; p.T435T; 11:65654729-65654729

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1518G>A; p.G506G; 11:65654516-65654516

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.354C>T; p.I118I; 11:65660197-65660197

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.942G>T; p.K314N; 11:65655871-65655871

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.989G>A; p.R330H; 11:65655732-65655732

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.276A>G; p.G92G; 11:65661746-65661746

 central_nervous_system; braingliomaSubstitution - coding silent

c.1459C>T; p.H487Y; 11:65654575-65654575

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.379G>C; p.E127Q; 11:65660172-65660172

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1519G>A; p.A507T; 11:65654515-65654515

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1533delC; p.D512fs*35; 11:65654501-65654501

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.305C>T; p.A102V; 11:65661717-65661717

 skinmalignant_melanomaSubstitution - Missense

c.191A>G; p.N64S; 11:65661831-65661831

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.392G>C; p.S131T; 11:65660159-65660159

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1492G>A; p.E498K; 11:65654542-65654542

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1336G>C; p.D446H; 11:65654698-65654698

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.447T>G; p.R149R; 11:65659778-65659778

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.819G>A; p.R273R; 11:65658345-65658345

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.447T>G; p.R149R; 11:65659778-65659778

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.686C>T; p.T229M; 11:65658478-65658478

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.472C>T; p.R158W; 11:65659753-65659753

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.833G>A; p.R278Q; 11:65658331-65658331

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1565G>A; p.G522E; 11:65654469-65654469

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1586C>T; p.S529L; 11:65654448-65654448

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1586C>T; p.S529L; 11:65654448-65654448

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.435A>G; p.I145M; 11:65659790-65659790

 breastcarcinomaSubstitution - Missense

c.1586C>T; p.S529L; 11:65654448-65654448

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.379G>T; p.E127*; 11:65660172-65660172

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.969C>T; p.D323D; 11:65655752-65655752

 skinmalignant_melanomaSubstitution - coding silent

c.829G>A; p.D277N; 11:65658335-65658335

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.748A>G; p.I250V; 11:65658416-65658416

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.456C>T; p.Y152Y; 11:65659769-65659769

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.703G>T; p.A235S; 11:65658461-65658461

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.703G>T; p.A235S; 11:65658461-65658461

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1123C>T; p.Q375*; 11:65654911-65654911

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.827C>T; p.S276F; 11:65658337-65658337

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.19_20insC; p.L7fs*19; 11:65662193-65662194

 oesophaguscarcinoma; adenocarcinomaInsertion - Frameshift

c.592C>T; p.R198*; 11:65658790-65658790

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Nonsense

c.592C>T; p.R198*; 11:65658790-65658790

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.355C>A; p.Q119K; 11:65660196-65660196

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.1450G>A; p.V484M; 11:65654584-65654584

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

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