Entrez Gene

Basic Information
Gene ID	5934
Name	RBL2
Synonymous	retinoblastoma-like 2;RBL2;retinoblastoma-like 2
Definition	130 kDa retinoblastoma-associated protein\|PRB2\|RBR-2\|retinoblastoma-like protein 2\|retinoblastoma-related protein 2
Position	16q12.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1836T>G; p.N612K; 16:53465575-53465575	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1639C>G; p.P547A; 16:53464304-53464304	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2167C>T; p.P723S; 16:53470107-53470107	oesophagus	carcinoma	Substitution - Missense
c.1929C>T; p.P643P; 16:53467123-53467123	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1640C>A; p.P547H; 16:53464305-53464305	large_intestine; rectum	NS	Substitution - Missense
c.3419G>A; p.1140; 16:53490299-53490299	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2109A>G; p.L703L; 16:53470049-53470049	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3208C>A; p.R1070R; 16:53481794-53481794	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3269G>T; p.S1090I; 16:53490149-53490149	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1781T>G; p.L594*; 16:53465520-53465520	liver	carcinoma	Substitution - Nonsense
c.1431C>T; p.D477D; 16:53461825-53461825	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1781T>G; p.L594*; 16:53465520-53465520	liver	carcinoma	Substitution - Nonsense
c.3035T>C; p.I1012T; 16:53480720-53480720	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.519C>T; p.I173I; 16:53442805-53442805	skin	malignant_melanoma	Substitution - coding silent
c.504C>A; p.P168P; 16:53442790-53442790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3035T>C; p.I1012T; 16:53480720-53480720	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3069G>A; p.K1023K; 16:53480754-53480754	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2888G>C; p.R963T; 16:53480573-53480573	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3104C>A; p.S1035Y; 16:53481690-53481690	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.547C>A; p.R183S; 16:53442833-53442833	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.881A>C; p.K294T; 16:53453566-53453566	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2255A>G; p.N752S; 16:53470392-53470392	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3008G>T; p.G1003V; 16:53480693-53480693	pancreas	carcinoma	Substitution - Missense
c.829G>A; p.E277K; 16:53453514-53453514	pancreas	carcinoma	Substitution - Missense
c.383T>A; p.F128Y; 16:53442669-53442669	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1014T>C; p.Y338Y; 16:53454677-53454677	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2225C>T; p.T742M; 16:53470165-53470165	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1580C>T; p.A527V; 16:53464245-53464245	skin	malignant_melanoma	Substitution - Missense
c.1510G>T; p.E504*; 16:53462605-53462605	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.506delT; p.Q171fs*47; 16:53442792-53442792	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.2768G>A; p.R923Q; 16:53479218-53479218	skin	malignant_melanoma	Substitution - Missense
c.2434C>T; p.P812S; 16:53470571-53470571	skin	malignant_melanoma	Substitution - Missense
c.1360G>T; p.D454Y; 16:53461754-53461754	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.381A>T; p.E127D; 16:53442667-53442667	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1360G>T; p.D454Y; 16:53461754-53461754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3313C>A; p.L1105I; 16:53490193-53490193	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3276A>G; p.I1092M; 16:53490156-53490156	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2224A>G; p.T742A; 16:53470164-53470164	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>T; p.E127*; 16:53442665-53442665	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1586A>G; p.H529R; 16:53464251-53464251	liver	carcinoma	Substitution - Missense
c.2694G>A; p.V898V; 16:53470913-53470913	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1586A>G; p.H529R; 16:53464251-53464251	liver	carcinoma	Substitution - Missense
c.3097C>A; p.P1033T; 16:53481683-53481683	skin	malignant_melanoma	Substitution - Missense
c.2258A>C; p.E753A; 16:53470395-53470395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2863G>T; p.E955*; 16:53479973-53479973	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1099A>G; p.R367G; 16:53454762-53454762	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1099A>G; p.R367G; 16:53454762-53454762	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1099A>G; p.R367G; 16:53454762-53454762	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1337A>C; p.Q446P; 16:53459608-53459608	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3192A>G; p.E1064E; 16:53481778-53481778	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3278G>A; p.R1093H; 16:53490158-53490158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.178G>C; p.E60Q; 16:53434734-53434734	pancreas	carcinoma	Substitution - Missense
c.1100G>A; p.R367K; 16:53454763-53454763	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1888A>G; p.R630G; 16:53467082-53467082	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2089C>T; p.R697C; 16:53470029-53470029	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.379G>A; p.E127K; 16:53442665-53442665	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.379G>A; p.E127K; 16:53442665-53442665	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>A; p.E127K; 16:53442665-53442665	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.379G>A; p.E127K; 16:53442665-53442665	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.379G>A; p.E127K; 16:53442665-53442665	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1614G>T; p.E538D; 16:53464279-53464279	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>A; p.E127K; 16:53442665-53442665	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2704G>A; p.V902I; 16:53479154-53479154	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1275C>T; p.S425S; 16:53459546-53459546	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3026_3028delACA; p.N1011delN; 16:53480711-53480713	liver	carcinoma; hepatocellular_carcinoma	Deletion - In frame
c.1342C>A; p.L448I; 16:53459613-53459613	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1414C>T; p.Q472*; 16:53461808-53461808	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.445A>T; p.T149S; 16:53442731-53442731	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1414C>T; p.Q472*; 16:53461808-53461808	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1948C>T; p.R650C; 16:53467142-53467142	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1948C>T; p.R650C; 16:53467142-53467142	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2103G>A; p.Q701Q; 16:53470043-53470043	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1948C>T; p.R650C; 16:53467142-53467142	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3329G>A; p.S1110N; 16:53490209-53490209	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1237A>C; p.S413R; 16:53459508-53459508	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100G>T; p.R367M; 16:53454763-53454763	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1329A>G; p.K443K; 16:53459600-53459600	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3300A>C; p.K1100N; 16:53490180-53490180	liver	carcinoma	Substitution - Missense
c.1059T>A; p.F353L; 16:53454722-53454722	liver	carcinoma	Substitution - Missense
c.3389A>G; p.Q1130R; 16:53490269-53490269	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1477C>T; p.R493C; 16:53462572-53462572	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2504C>A; p.S835Y; 16:53470641-53470641	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1477C>T; p.R493C; 16:53462572-53462572	skin	malignant_melanoma	Substitution - Missense
c.1477C>T; p.R493C; 16:53462572-53462572	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2053G>C; p.E685Q; 16:53469993-53469993	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1536A>C; p.K512N; 16:53462631-53462631	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.729T>C; p.C243C; 16:53451794-53451794	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.3024C>G; p.F1008L; 16:53480709-53480709	urinary_tract; bladder	carcinoma	Substitution - Missense
c.809C>T; p.S270F; 16:53453494-53453494	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.503C>T; p.P168L; 16:53442789-53442789	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.461G>A; p.R154K; 16:53442747-53442747	skin	malignant_melanoma	Substitution - Missense
c.503C>T; p.P168L; 16:53442789-53442789	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.503C>T; p.P168L; 16:53442789-53442789	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3380G>A; p.R1127H; 16:53490260-53490260	ovary	other; neoplasm	Substitution - Missense
c.1884G>T; p.L628L; 16:53467078-53467078	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.593C>T; p.S198F; 16:53447062-53447062	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.3143T>A; p.I1048K; 16:53481729-53481729	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.593C>T; p.S198F; 16:53447062-53447062	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1682T>C; p.L561P; 16:53464347-53464347	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.369G>C; p.Q123H; 16:53439144-53439144	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2708C>A; p.T903K; 16:53479158-53479158	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2703+6T>C; p.?; 16:53470928-53470928	stomach	adenocarcinoma	Unknown
c.1927C>T; p.P643S; 16:53467121-53467121	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2766C>A; p.A922A; 16:53479216-53479216	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2405C>G; p.P802R; 16:53470542-53470542	thyroid	carcinoma	Substitution - Missense
c.898C>A; p.P300T; 16:53453583-53453583	skin	malignant_melanoma	Substitution - Missense
c.1101G>A; p.R367R; 16:53454764-53454764	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3211G>T; p.E1071*; 16:53481797-53481797	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1957A>G; p.T653A; 16:53467151-53467151	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1385G>A; p.R462K; 16:53461779-53461779	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1522G>A; p.E508K; 16:53462617-53462617	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2590T>C; p.L864L; 16:53470809-53470809	thyroid	other; neoplasm	Substitution - coding silent
c.813delC; p.P273fs*14; 16:53453498-53453498	pancreas	carcinoma; acinar_carcinoma	Deletion - Frameshift
c.872A>C; p.K291T; 16:53453557-53453557	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.2945G>A; p.S982N; 16:53480630-53480630	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.55G>A; p.A19T; 16:53434611-53434611	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.629A>G; p.Y210C; 16:53447098-53447098	thyroid	other; neoplasm	Substitution - Missense
c.1837G>T; p.E613*; 16:53465576-53465576	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1938G>T; p.V646V; 16:53467132-53467132	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.196G>A; p.A66T; 16:53434752-53434752	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2279T>G; p.F760C; 16:53470416-53470416	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.260T>C; p.L87S; 16:53439035-53439035	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2078G>A; p.G693E; 16:53470018-53470018	liver	carcinoma	Substitution - Missense
c.2078G>A; p.G693E; 16:53470018-53470018	liver	carcinoma	Substitution - Missense
c.2528T>C; p.V843A; 16:53470747-53470747	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2783G>A; p.R928K; 16:53479893-53479893	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.899C>G; p.P300R; 16:53453584-53453584	skin	malignant_melanoma	Substitution - Missense
c.2176A>G; p.T726A; 16:53470116-53470116	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2143G>A; p.E715K; 16:53470083-53470083	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1727_1750del24; p.D576_K584>E; 16:53465466-53465489	lung	carcinoma; small_cell_carcinoma	Complex - deletion inframe
c.2250T>C; p.I750I; 16:53470387-53470387	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2966G>A; p.R989H; 16:53480651-53480651	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1617C>G; p.V539V; 16:53464282-53464282	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1641T>C; p.P547P; 16:53464306-53464306	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2855C>G; p.S952C; 16:53479965-53479965	ovary	other; neoplasm	Substitution - Missense
c.813C>T; p.D271D; 16:53453498-53453498	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.522T>G; p.F174L; 16:53442808-53442808	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1681C>T; p.L561F; 16:53464346-53464346	skin; trunk	malignant_melanoma	Substitution - Missense
c.547C>T; p.R183C; 16:53442833-53442833	breast	carcinoma	Substitution - Missense
c.520T>C; p.F174L; 16:53442806-53442806	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2100delA; p.Q701fs*3; 16:53470040-53470040	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Deletion - Frameshift
c.1092T>G; p.T364T; 16:53454755-53454755	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1532delA; p.R513fs*2; 16:53462627-53462627	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.574C>T; p.R192*; 16:53447043-53447043	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1393G>T; p.E465*; 16:53461787-53461787	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1393G>T; p.E465*; 16:53461787-53461787	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.574C>T; p.R192*; 16:53447043-53447043	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.574C>T; p.R192*; 16:53447043-53447043	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1393G>T; p.E465*; 16:53461787-53461787	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2975G>T; p.G992V; 16:53480660-53480660	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1478G>A; p.R493H; 16:53462573-53462573	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3282A>C; p.T1094T; 16:53490162-53490162	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1423C>G; p.Q475E; 16:53461817-53461817	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2128C>T; p.Q710*; 16:53470068-53470068	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3337C>T; p.P1113S; 16:53490217-53490217	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.788C>T; p.A263V; 16:53453473-53453473	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3139C>T; p.R1047*; 16:53481725-53481725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.503C>A; p.P168H; 16:53442789-53442789	liver	carcinoma	Substitution - Missense
c.503C>A; p.P168H; 16:53442789-53442789	liver	carcinoma	Substitution - Missense
c.1386A>T; p.R462S; 16:53461780-53461780	prostate	carcinoma	Substitution - Missense
c.3277C>T; p.R1093C; 16:53490157-53490157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1139delG; p.V381fs*3; 16:53454802-53454802	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.2360G>C; p.G787A; 16:53470497-53470497	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2467G>A; p.V823I; 16:53470604-53470604	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2467G>A; p.V823I; 16:53470604-53470604	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.403T>C; p.W135R; 16:53442689-53442689	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2740C>T; p.R914C; 16:53479190-53479190	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.513G>A; p.Q171Q; 16:53442799-53442799	skin	malignant_melanoma	Substitution - coding silent
c.2329A>T; p.I777F; 16:53470466-53470466	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.872_873insG; p.I293fs*11; 16:53453557-53453558	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.453A>G; p.R151R; 16:53442739-53442739	liver	carcinoma	Substitution - coding silent
c.1764G>A; p.Q588Q; 16:53465503-53465503	breast	carcinoma; HER-positive_carcinoma	Substitution - coding silent
c.2432C>T; p.S811F; 16:53470569-53470569	skin	malignant_melanoma	Substitution - Missense
c.1248G>A; p.V416V; 16:53459519-53459519	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.738T>C; p.R246R; 16:53451803-53451803	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.920delA; p.K309fs*14; 16:53453605-53453605	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.920delA; p.K309fs*14; 16:53453605-53453605	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.3107C>T; p.P1036L; 16:53481693-53481693	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1097C>T; p.S366L; 16:53454760-53454760	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3120A>T; p.V1040V; 16:53481706-53481706	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2511G>A; p.S837S; 16:53470648-53470648	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2284G>C; p.V762L; 16:53470421-53470421	urinary_tract; bladder	carcinoma	Substitution - Missense
c.658G>T; p.D220Y; 16:53451723-53451723	skin	malignant_melanoma	Substitution - Missense
c.2914A>G; p.S972G; 16:53480599-53480599	central_nervous_system; brain	glioma; oligodendroglioma_Grade_III	Substitution - Missense
c.496T>A; p.Y166N; 16:53442782-53442782	liver	carcinoma	Substitution - Missense
c.496T>A; p.Y166N; 16:53442782-53442782	liver	carcinoma	Substitution - Missense
c.535G>A; p.E179K; 16:53442821-53442821	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2090G>A; p.R697H; 16:53470030-53470030	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.509T>C; p.F170S; 16:53442795-53442795	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.47C>T; p.P16L; 16:53434603-53434603	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1432G>T; p.E478*; 16:53461826-53461826	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.536A>C; p.E179A; 16:53442822-53442822	liver	carcinoma	Substitution - Missense
c.1111G>A; p.A371T; 16:53454774-53454774	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.536A>C; p.E179A; 16:53442822-53442822	liver	carcinoma	Substitution - Missense
c.3361A>C; p.N1121H; 16:53490241-53490241	stomach	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]