Entrez Gene

Basic Information
Gene ID	5901
Name	RAN
Synonymous	RAN, member RAS oncogene family;RAN;RAN, member RAS oncogene family
Definition	GTP-binding nuclear protein Ran\|GTPase Ran\|OK/SW-cl.81\|RanGTPase\|androgen receptor-associated protein 24\|guanosine triphosphatase Ran\|member RAS oncogene family\|ras-like protein TC4\|ras-related nuclear protein
Position	12q24.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.380A>C; p.K127T; 12:130874678-130874678	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.281C>T; p.S94L; 12:130874579-130874579	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.37-1G>T; p.?; 12:130872835-130872835	skin	malignant_melanoma	Unknown
c.418C>T; p.R140*; 12:130874716-130874716	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.329delG; p.R110fs*22; 12:130874627-130874627	breast	carcinoma	Deletion - Frameshift
c.244C>T; p.Q82*; 12:130873125-130873125	skin	malignant_melanoma	Substitution - Nonsense
c.328C>T; p.R110*; 12:130874626-130874626	soft_tissue; fat	liposarcoma; myxoid-round_cell	Substitution - Nonsense
c.530T>C; p.V177A; 12:130875706-130875706	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.419G>A; p.R140Q; 12:130874717-130874717	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.419G>A; p.R140Q; 12:130874717-130874717	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.88C>T; p.H30Y; 12:130872887-130872887	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.51T>G; p.G17G; 12:130872850-130872850	thyroid	other; neoplasm	Substitution - coding silent
c.84A>G; p.K28K; 12:130872883-130872883	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.547G>A; p.A183T; 12:130875723-130875723	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.414C>T; p.F138F; 12:130874712-130874712	skin	malignant_melanoma	Substitution - coding silent
c.358T>A; p.C120S; 12:130874656-130874656	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.210G>T; p.E70D; 12:130873091-130873091	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.312G>A; p.W104*; 12:130874610-130874610	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.271G>A; p.D91N; 12:130874569-130874569	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.149T>C; p.L50P; 12:130873030-130873030	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.95C>T; p.T32I; 12:130872894-130872894	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.435+5G>T; p.?; 12:130874738-130874738	lung	carcinoma; non_small_cell_carcinoma	Unknown
c.467A>G; p.N156S; 12:130875643-130875643	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.467A>G; p.N156S; 12:130875643-130875643	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.504C>T; p.L168L; 12:130875680-130875680	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.303G>A; p.V101V; 12:130874601-130874601	breast	carcinoma	Substitution - coding silent
c.107_109delAGA; p.K38delK; 12:130872906-130872908	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Deletion - In frame
c.169G>T; p.G57*; 12:130873050-130873050	pancreas	carcinoma	Substitution - Nonsense
c.537G>A; p.M179I; 12:130875713-130875713	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.37-1G>A; p.?; 12:130872835-130872835	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.52G>T; p.D18Y; 12:130872851-130872851	urinary_tract; bladder	carcinoma	Substitution - Missense
c.562G>T; p.V188F; 12:130875738-130875738	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.161C>T; p.T54I; 12:130873042-130873042	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.282G>T; p.S94S; 12:130874580-130874580	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]