Entrez Gene

Basic Information
Gene ID	51024
Name	FIS1
Synonymous	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae);FIS1;fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Definition	FIS1 homolog\|H_NH0132A01.6\|TPR repeat protein 11\|hFis1\|mitochondrial fission 1 protein\|tetratricopeptide repeat domain 11\|tetratricopeptide repeat protein 11
Position	7q22.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.235G>A; p.V79M; 7:101240850-101240850	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.443C>T; p.S148F; 7:101239822-101239822	skin	malignant_melanoma	Substitution - Missense
c.349G>T; p.A117S; 7:101240154-101240154	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.393C>T; p.G131G; 7:101239872-101239872	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.28T>G; p.S10A; 7:101244977-101244977	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.161G>A; p.G54D; 7:101244024-101244024	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.161G>A; p.G54D; 7:101244024-101244024	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.211C>T; p.R71W; 7:101240874-101240874	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.91T>G; p.S31A; 7:101244094-101244094	pancreas	carcinoma	Substitution - Missense
c.249G>T; p.R83R; 7:101240836-101240836	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.124C>T; p.L42L; 7:101244061-101244061	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.79G>T; p.A27S; 7:101244106-101244106	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.439G>A; p.V147M; 7:101239826-101239826	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.439G>A; p.V147M; 7:101239826-101239826	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.410C>T; p.A137V; 7:101239855-101239855	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.410C>T; p.A137V; 7:101239855-101239855	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.403G>A; p.G135S; 7:101239862-101239862	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.215A>G; p.D72G; 7:101240870-101240870	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.231G>T; p.L77L; 7:101240854-101240854	skin	malignant_melanoma	Substitution - coding silent
c.373_382del10; p.G125fs*>25; 7:101239883-101239892	liver	carcinoma	Deletion - Frameshift
c.114C>T; p.Y38Y; 7:101244071-101244071	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.233C>T; p.A78V; 7:101240852-101240852	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.284G>A; p.R95H; 7:101240219-101240219	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.206A>G; p.E69G; 7:101240879-101240879	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.85T>A; p.S29T; 7:101244100-101244100	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.85T>A; p.S29T; 7:101244100-101244100	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense

COSMIC somatic mutation [Top]