Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

445

Name

ASS1

Synonymous

argininosuccinate synthase 1;ASS1;argininosuccinate synthase 1

Definition

argininosuccinate synthase|argininosuccinate synthetase 1|citrulline--aspartate ligase|citrulline-aspartate ligase

Position

9q34.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1074G>A; p.V358V; 9:130494970-130494970

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.88G>A; p.D30N; 9:130452316-130452316

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.979C>T; p.H327Y; 9:130494875-130494875

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.676G>A; p.E226K; 9:130476949-130476949

 skinmalignant_melanomaSubstitution - Missense

c.861C>A; p.G287G; 9:130489355-130489355

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.861C>A; p.G287G; 9:130489355-130489355

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.457C>T; p.R153W; 9:130466761-130466761

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.804C>T; p.I268I; 9:130480415-130480415

 skinmalignant_melanomaSubstitution - coding silent

c.629C>T; p.T210I; 9:130476902-130476902

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.704T>C; p.V235A; 9:130479731-130479731

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.253G>T; p.D85Y; 9:130458479-130458479

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.321G>A; p.Q107Q; 9:130458547-130458547

 skinmalignant_melanomaSubstitution - coding silent

c.39C>T; p.G13G; 9:130452267-130452267

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.566+1G>A; p.?; 9:130470905-130470905

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1008C>T; p.H336H; 9:130494904-130494904

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.132C>T; p.F44F; 9:130454331-130454331

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.945G>C; p.L315F; 9:130489439-130489439

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.682A>T; p.K228*; 9:130476955-130476955

 thyroidother; neoplasmSubstitution - Nonsense

c.1027G>A; p.E343K; 9:130494923-130494923

 skinmalignant_melanomaSubstitution - Missense

c.846C>T; p.Y282Y; 9:130489340-130489340

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.722G>A; p.G241D; 9:130479749-130479749

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1022C>T; p.S341F; 9:130494918-130494918

 skinmalignant_melanomaSubstitution - Missense

c.558G>A; p.M186I; 9:130470896-130470896

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.379C>T; p.R127W; 9:130464126-130464126

 skinmalignant_melanomaSubstitution - Missense

c.919C>T; p.R307C; 9:130489413-130489413

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.258C>A; p.R86R; 9:130458484-130458484

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1235A>C; p.K412T; 9:130501017-130501017

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.978G>A; p.W326*; 9:130494874-130494874

 skinmalignant_melanomaSubstitution - Nonsense

c.1062C>G; p.L354L; 9:130494958-130494958

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.718G>A; p.D240N; 9:130479745-130479745

 skinmalignant_melanomaSubstitution - Missense

c.814C>T; p.R272C; 9:130480425-130480425

 central_nervous_system; brainglioma; astrocytoma_Grade_IIISubstitution - Missense

c.1141G>A; p.G381S; 9:130499518-130499518

 skin; upper_legmalignant_melanomaSubstitution - Missense

c.1035G>A; p.V345V; 9:130494931-130494931

 skinmalignant_melanomaSubstitution - coding silent

c.836G>C; p.R279P; 9:130480447-130480447

 breastcarcinomaSubstitution - Missense

c.775G>A; p.G259S; 9:130480386-130480386

 skinmalignant_melanomaSubstitution - Missense

c.775G>A; p.G259S; 9:130480386-130480386

 skinmalignant_melanomaSubstitution - Missense

c.583C>T; p.L195L; 9:130471501-130471501

 skinmalignant_melanomaSubstitution - coding silent

c.1003C>T; p.R335C; 9:130494899-130494899

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.501C>T; p.H167H; 9:130470839-130470839

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.331G>A; p.A111T; 9:130458557-130458557

 skinmalignant_melanomaSubstitution - Missense

c.658C>T; p.P220S; 9:130476931-130476931

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.824G>A; p.G275E; 9:130480435-130480435

 skinmalignant_melanomaSubstitution - Missense

c.437G>A; p.R146K; 9:130466741-130466741

 skinmalignant_melanomaSubstitution - Missense

c.1088G>A; p.R363Q; 9:130494984-130494984

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.856G>A; p.A286T; 9:130489350-130489350

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.786C>T; p.G262G; 9:130480397-130480397

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.65T>G; p.V22G; 9:130452293-130452293

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.190G>T; p.V64F; 9:130458416-130458416

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.605C>T; p.A202V; 9:130476878-130476878

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.717G>T; p.K239N; 9:130479744-130479744

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.941G>A; p.G314D; 9:130489435-130489435

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.624G>A; p.T208T; 9:130476897-130476897

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.17C>T; p.S6F; 9:130452245-130452245

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.571G>A; p.E191K; 9:130471489-130471489

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.310G>A; p.E104K; 9:130458536-130458536

 skinmalignant_melanomaSubstitution - Missense

c.470G>A; p.R157H; 9:130466774-130466774

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.416T>C; p.I139T; 9:130464163-130464163

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.963G>A; p.V321V; 9:130489457-130489457

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.198G>A; p.R66R; 9:130458424-130458424

 skinmalignant_melanomaSubstitution - coding silent

c.345C>T; p.S115S; 9:130458571-130458571

 skinmalignant_melanomaSubstitution - coding silent

c.582_583CC>TT; p.(=); 9:130471500-130471501

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.613G>A; p.G205S; 9:130476886-130476886

 skinmalignant_melanomaSubstitution - Missense

c.234G>A; p.Q78Q; 9:130458460-130458460

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.597+8C>T; p.?; 9:130471523-130471523

 livercarcinoma; hepatocellular_carcinomaUnknown

c.534G>A; p.P178P; 9:130470872-130470872

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.374A>G; p.Q125R; 9:130464121-130464121

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.352G>A; p.A118T; 9:130458578-130458578

 livercarcinomaSubstitution - Missense

c.352G>A; p.A118T; 9:130458578-130458578

 livercarcinomaSubstitution - Missense

c.352G>A; p.A118T; 9:130458578-130458578

 livercarcinomaSubstitution - Missense

c.352G>A; p.A118T; 9:130458578-130458578

 livercarcinomaSubstitution - Missense

c.843C>G; p.I281M; 9:130489337-130489337

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.349G>A; p.G117S; 9:130458575-130458575

 central_nervous_system; braingliomaSubstitution - Missense

c.955G>T; p.E319*; 9:130489449-130489449

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Nonsense

c.965A>G; p.Y322C; 9:130489459-130489459

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.489C>T; p.Y163Y; 9:130466793-130466793

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.891C>T; p.I297I; 9:130489385-130489385

 skinmalignant_melanomaSubstitution - coding silent

c.670G>A; p.E224K; 9:130476943-130476943

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.772G>A; p.A258T; 9:130479799-130479799

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1057G>A; p.V353I; 9:130494953-130494953

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.322C>T; p.R108W; 9:130458548-130458548

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.920G>A; p.R307H; 9:130489414-130489414

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.920G>A; p.R307H; 9:130489414-130489414

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1016C>A; p.A339D; 9:130494912-130494912

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1227C>A; p.V409V; 9:130501009-130501009

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.175-5C>G; p.?; 9:130458396-130458396

 ovaryother; neoplasmUnknown

c.794G>A; p.R265H; 9:130480405-130480405

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.440T>C; p.M147T; 9:130466744-130466744

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

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