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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4316

Name

MMP7

Synonymous

matrix metallopeptidase 7;MMP7;matrix metallopeptidase 7

Definition

matrilysin|matrin|matrix metallopeptidase 7 (matrilysin, uterine)|matrix metalloproteinase 7 (matrilysin, uterine)|matrix metalloproteinase-7|pump-1 protease|uterine matrilysin|uterine metalloproteinase

Position

11q22.2

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.340G>A; p.V114I; 11:102527668-102527668

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.703A>G; p.T235A; 11:102523312-102523312

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.410G>A; p.G137D; 11:102527598-102527598

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.152_153insA; p.N51fs*51; 11:102527939-102527940

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.215G>T; p.G72V; 11:102527877-102527877

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.104C>T; p.A35V; 11:102530597-102530597

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.153T>C; p.N51N; 11:102527939-102527939

 livercarcinomaSubstitution - coding silent

c.153T>C; p.N51N; 11:102527939-102527939

 livercarcinomaSubstitution - coding silent

c.710G>A; p.G237E; 11:102523305-102523305

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.311G>A; p.W104*; 11:102527781-102527781

 skinmalignant_melanomaSubstitution - Nonsense

c.120G>C; p.K40N; 11:102527972-102527972

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.152delA; p.N51fs*5; 11:102527940-102527940

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.152delA; p.N51fs*5; 11:102527940-102527940

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.74G>A; p.G25E; 11:102530627-102530627

 skinmalignant_melanomaSubstitution - Missense

c.102G>T; p.Q34H; 11:102530599-102530599

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.493G>A; p.D165N; 11:102525056-102525056

 skinmalignant_melanomaSubstitution - Missense

c.561A>G; p.G187G; 11:102524988-102524988

 ovaryother; neoplasmSubstitution - coding silent

c.624C>T; p.F208F; 11:102523391-102523391

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.195C>A; p.F65L; 11:102527897-102527897

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.524C>T; p.T175M; 11:102525025-102525025

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.576C>T; p.F192F; 11:102524973-102524973

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.17T>C; p.L6P; 11:102530684-102530684

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.17T>C; p.L6P; 11:102530684-102530684

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.560G>A; p.G187E; 11:102524989-102524989

 skinmalignant_melanomaSubstitution - Missense

c.230G>A; p.R77H; 11:102527862-102527862

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.230G>A; p.R77H; 11:102527862-102527862

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.183G>T; p.E61D; 11:102527909-102527909

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.542C>T; p.A181V; 11:102525007-102525007

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.542C>T; p.A181V; 11:102525007-102525007

 livercarcinomaSubstitution - Missense

c.629A>G; p.Y210C; 11:102523386-102523386

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.542C>T; p.A181V; 11:102525007-102525007

 livercarcinomaSubstitution - Missense

c.525G>A; p.T175T; 11:102525024-102525024

 livercarcinomaSubstitution - coding silent

c.479G>A; p.R160Q; 11:102527529-102527529

 skinmalignant_melanomaSubstitution - Missense

c.479G>A; p.R160Q; 11:102527529-102527529

 skinmalignant_melanomaSubstitution - Missense

c.479G>A; p.R160Q; 11:102527529-102527529

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.76G>A; p.G26S; 11:102530625-102530625

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.379C>T; p.R127*; 11:102527629-102527629

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.203T>A; p.L68Q; 11:102527889-102527889

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.75A>G; p.G25G; 11:102530626-102530626

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.464T>C; p.M155T; 11:102527544-102527544

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.559G>A; p.G187R; 11:102524990-102524990

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.559G>A; p.G187R; 11:102524990-102524990

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.492G>T; p.G164G; 11:102525057-102525057

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.435G>A; p.R145R; 11:102527573-102527573

 skinmalignant_melanomaSubstitution - coding silent

c.351T>C; p.T117T; 11:102527657-102527657

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.22G>A; p.A8T; 11:102530679-102530679

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.590G>A; p.R197H; 11:102524959-102524959

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1A>G; p.M1V; 11:102530700-102530700

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.749A>G; p.D250G; 11:102523266-102523266

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.295C>T; p.P99S; 11:102527797-102527797

 skinmalignant_melanomaSubstitution - Missense

c.387G>A; p.V129V; 11:102527621-102527621

 skinmalignant_melanomaSubstitution - coding silent

c.352C>T; p.R118*; 11:102527656-102527656

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.16C>A; p.L6M; 11:102530685-102530685

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.5G>A; p.R2Q; 11:102530696-102530696

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.231C>A; p.R77R; 11:102527861-102527861

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.476C>G; p.A159G; 11:102527532-102527532

 prostatecarcinomaSubstitution - Missense

c.232G>A; p.V78I; 11:102527860-102527860

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.232G>A; p.V78I; 11:102527860-102527860

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.232G>A; p.V78I; 11:102527860-102527860

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.543G>A; p.A181A; 11:102525006-102525006

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.726A>G; p.Q242Q; 11:102523289-102523289

 skinmalignant_melanomaSubstitution - coding silent

c.631G>T; p.A211S; 11:102523384-102523384

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

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