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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3805

Name

KIR2DL4

Synonymous

killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4;KIR2DL4;killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4

Definition

CD158 antigen-like family member D|MHC class I NK cell receptor KIR103AS|NK cell receptor|killer Ig receptor|killer cell immunoglobulin-like receptor 2DL4|killer cell inhibitory receptor 103AS|natural killer cell inhibitory receptor

Position

19q13.4

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.201G>C; p.G67G; 19:54804917-54804917

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.160C>A; p.R54S; 19:54804876-54804876

 NSNSSubstitution - Missense

c.213T>G; p.P71P; 19:54804929-54804929

 thyroidother; neoplasmSubstitution - coding silent

c.115G>A; p.A39T; 19:54804831-54804831

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.115G>A; p.A39T; 19:54804831-54804831

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.810A>C; p.K270N; 19:54813228-54813228

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.48C>T; p.F16F; 19:54803898-54803898

 skinmalignant_melanomaSubstitution - coding silent

c.625C>G; p.P209A; 19:54806214-54806214

 thyroidother; neoplasmSubstitution - Missense

c.626C>T; p.P209L; 19:54806215-54806215

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.96C>T; p.F32F; 19:54804812-54804812

 skinmalignant_melanomaSubstitution - coding silent

c.301C>T; p.H101Y; 19:54805017-54805017

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.114C>T; p.S38S; 19:54804830-54804830

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.273C>T; p.H91H; 19:54804989-54804989

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.148C>T; p.R50W; 19:54804864-54804864

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.376C>T; p.P126S; 19:54805965-54805965

 breastcarcinomaSubstitution - Missense

c.326C>T; p.S109L; 19:54805042-54805042

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.783C>T; p.L261L; 19:54813201-54813201

 skinmalignant_melanomaSubstitution - coding silent

c.711C>T; p.I237I; 19:54813129-54813129

 skinmalignant_melanomaSubstitution - coding silent

c.497T>A; p.L166H; 19:54806086-54806086

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.712G>C; p.A238P; 19:54813130-54813130

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.61G>T; p.V21L; 19:54803911-54803911

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.802delA; p.M271fs*>3; 19:54813220-54813220

 ovarycarcinoma; serous_carcinomaDeletion - Frameshift

c.762T>C; p.F254F; 19:54813180-54813180

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.762T>C; p.F254F; 19:54813180-54813180

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.762T>C; p.F254F; 19:54813180-54813180

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.762T>C; p.F254F; 19:54813180-54813180

 breastcarcinomaSubstitution - coding silent

c.28C>T; p.L10L; 19:54803679-54803679

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.410G>A; p.R137H; 19:54805999-54805999

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.410G>A; p.R137H; 19:54805999-54805999

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.497T>G; p.L166R; 19:54806086-54806086

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.497T>G; p.L166R; 19:54806086-54806086

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.810+6C>T; p.?; 19:54813234-54813234

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.55C>A; p.Q19K; 19:54803905-54803905

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.790C>T; p.R264C; 19:54813208-54813208

 skinmalignant_melanomaSubstitution - Missense

c.810+4A>G; p.?; 19:54813232-54813232

 skinmalignant_melanomaUnknown

c.412G>A; p.A138T; 19:54806001-54806001

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.412G>A; p.A138T; 19:54806001-54806001

 breastcarcinomaSubstitution - Missense

c.412G>A; p.A138T; 19:54806001-54806001

 thyroidother; neoplasmSubstitution - Missense

c.680C>G; p.S227*; 19:54808857-54808857

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.160C>T; p.R54C; 19:54804876-54804876

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.160C>T; p.R54C; 19:54804876-54804876

 large_intestineadenomaSubstitution - Missense

c.187T>C; p.Y63H; 19:54804903-54804903

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.509C>A; p.A170E; 19:54806098-54806098

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.377C>T; p.P126L; 19:54805966-54805966

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.377C>T; p.P126L; 19:54805966-54805966

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.764C>T; p.T255I; 19:54813182-54813182

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.480delG; p.E162fs*83; 19:54806069-54806069

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.411C>T; p.R137R; 19:54806000-54806000

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.149G>A; p.R50Q; 19:54804865-54804865

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.149G>A; p.R50Q; 19:54804865-54804865

 prostatecarcinomaSubstitution - Missense

c.149G>A; p.R50Q; 19:54804865-54804865

 skinmalignant_melanomaSubstitution - Missense

c.182C>T; p.T61M; 19:54804898-54804898

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.182C>T; p.T61M; 19:54804898-54804898

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.345G>T; p.L115L; 19:54805061-54805061

 livercarcinomaSubstitution - coding silent

c.345G>T; p.L115L; 19:54805061-54805061

 livercarcinomaSubstitution - coding silent

c.149G>A; p.R50Q; 19:54804865-54804865

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.559G>A; p.A187T; 19:54806148-54806148

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.38T>A; p.L13H; 19:54803689-54803689

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.183G>C; p.T61T; 19:54804899-54804899

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

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