Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3663

Name

IRF5

Synonymous

interferon regulatory factor 5;IRF5;interferon regulatory factor 5

Definition

-

Position

7q32

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.216G>A; p.G72G; 7:128945865-128945865

 skinmalignant_melanomaSubstitution - coding silent

c.33A>C; p.P11P; 7:128942114-128942114

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.33A>C; p.P11P; 7:128942114-128942114

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.33A>C; p.P11P; 7:128942114-128942114

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.215G>A; p.G72E; 7:128945864-128945864

 skinmalignant_melanomaSubstitution - Missense

c.830G>A; p.G277D; 7:128947801-128947801

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1026C>T; p.A342A; 7:128947997-128947997

 skinmalignant_melanomaSubstitution - coding silent

c.209A>T; p.E70V; 7:128945858-128945858

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.271C>T; p.R91C; 7:128945920-128945920

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1189C>T; p.P397S; 7:128948248-128948248

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.121A>C; p.K41Q; 7:128942202-128942202

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1169A>G; p.K390R; 7:128948228-128948228

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.632G>A; p.G211D; 7:128947410-128947410

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1170G>A; p.K390K; 7:128948229-128948229

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.272G>A; p.R91H; 7:128945921-128945921

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.272G>A; p.R91H; 7:128945921-128945921

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.272G>A; p.R91H; 7:128945921-128945921

 pancreascarcinomaSubstitution - Missense

c.990G>A; p.G330G; 7:128947961-128947961

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.393_394insC; p.E134fs*1; 7:128946508-128946509

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.94G>T; p.G32W; 7:128942175-128942175

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.960G>A; p.T320T; 7:128947931-128947931

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.457A>T; p.M153L; 7:128947032-128947032

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.781C>T; p.Q261*; 7:128947752-128947752

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.769G>A; p.E257K; 7:128947740-128947740

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1121A>G; p.K374R; 7:128948092-128948092

 skinmalignant_melanomaSubstitution - Missense

c.376G>T; p.A126S; 7:128946025-128946025

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.1116G>T; p.K372N; 7:128948087-128948087

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.651G>A; p.R217R; 7:128947429-128947429

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.804G>A; p.R268R; 7:128947775-128947775

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1434G>T; p.Q478H; 7:128948737-128948737

 thyroidcarcinomaSubstitution - Missense

c.1251G>A; p.K417K; 7:128948310-128948310

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1251G>A; p.K417K; 7:128948310-128948310

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.114G>A; p.G38G; 7:128942195-128942195

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.323G>A; p.R108Q; 7:128945972-128945972

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.829G>A; p.G277S; 7:128947800-128947800

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.61C>T; p.L21L; 7:128942142-128942142

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.802C>T; p.R268W; 7:128947773-128947773

 skinmalignant_melanomaSubstitution - Missense

c.1077C>A; p.A359A; 7:128948048-128948048

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1083C>T; p.D361D; 7:128948054-128948054

 breastcarcinomaSubstitution - coding silent

c.510A>G; p.T170T; 7:128947258-128947258

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1421A>G; p.Q474R; 7:128948724-128948724

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1248G>T; p.E416D; 7:128948307-128948307

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.950G>A; p.R317H; 7:128947921-128947921

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.354C>T; p.Y118Y; 7:128946003-128946003

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.273C>A; p.R91R; 7:128945922-128945922

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.136C>T; p.P46S; 7:128942217-128942217

 skinmalignant_melanomaSubstitution - Missense

c.1042T>C; p.C348R; 7:128948013-128948013

 livercarcinomaSubstitution - Missense

c.1042T>C; p.C348R; 7:128948013-128948013

 livercarcinomaSubstitution - Missense

c.543-1_571del30; p.?; 7:128947320-128947349

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.911G>A; p.R304H; 7:128947882-128947882

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.911G>A; p.R304H; 7:128947882-128947882

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.986G>A; p.R329H; 7:128947957-128947957

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.433G>A; p.E145K; 7:128946548-128946548

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.465A>T; p.P155P; 7:128947040-128947040

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.348G>C; p.K116N; 7:128945997-128945997

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 thyroidother; neoplasmSubstitution - coding silent

c.487G>A; p.V163M; 7:128947235-128947235

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 thyroidother; neoplasmSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; rectumNSSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.549T>C; p.P183P; 7:128947327-128947327

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1235G>A; p.R412H; 7:128948294-128948294

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.825C>G; p.P275P; 7:128947796-128947796

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1495C>T; p.H499Y; 7:128948798-128948798

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; rectumNSUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 ovarycarcinoma; serous_carcinomaUnknown

c.543-1G>A; p.?; 7:128947320-128947320

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1234C>T; p.R412C; 7:128948293-128948293

 stomachcarcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiableSubstitution - Missense

c.1170G>T; p.K390N; 7:128948229-128948229

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.176G>A; p.G59E; 7:128942257-128942257

 skinmalignant_melanomaSubstitution - Missense

c.1244G>A; p.R415Q; 7:128948303-128948303

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.176G>A; p.G59E; 7:128942257-128942257

 skinmalignant_melanomaSubstitution - Missense

c.542+8_549del30; p.?; 7:128947298-128947327

 breastcarcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 ovarycarcinoma; serous_carcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 ovarycarcinoma; serous_carcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 prostatecarcinoma; adenocarcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.542+8_549del30; p.?; 7:128947298-128947327

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaUnknown

c.1030C>T; p.R344C; 7:128948001-128948001

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.564C>T; p.P188P; 7:128947342-128947342

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.700C>T; p.P234S; 7:128947478-128947478

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.28A>C; p.T10P; 7:128942109-128942109

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.28A>C; p.T10P; 7:128942109-128942109

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.793C>T; p.R265W; 7:128947764-128947764

 pancreascarcinomaSubstitution - Missense

c.1158_1159CC>TT; p.(=); 7:128948217-128948218

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.1222G>A; p.E408K; 7:128948281-128948281

 skinmalignant_melanomaSubstitution - Missense

c.1507A>T; p.M503L; 7:128948810-128948810

 thyroidcarcinomaSubstitution - Missense

c.1222G>T; p.E408*; 7:128948281-128948281

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1302G>T; p.E434D; 7:128948605-128948605

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.41G>A; p.R14H; 7:128942122-128942122

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1254G>T; p.K418N; 7:128948313-128948313

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.198C>A; p.A66A; 7:128945847-128945847

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

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