Entrez Gene

Basic Information
Gene ID	3609
Name	ILF3
Synonymous	interleukin enhancer binding factor 3, 90kDa;ILF3;interleukin enhancer binding factor 3, 90kDa
Definition	M-phase phosphoprotein 4\|double-stranded RNA-binding protein, 76 kD\|dsRNA binding protein NFAR-2/MPP4\|interleukin enhancer binding factor 3, 90kD\|interleukin enhancer-binding factor 3\|nuclear factor associated with dsRNA\|nuclear factor of activated T-cell
Position	19p13.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1894G>A; p.E632K; 19:10683678-10683678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1450G>A; p.E484K; 19:10682606-10682606	urinary_tract; bladder	carcinoma	Substitution - Missense
c.65A>G; p.Y22C; 19:10671035-10671035	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1450G>A; p.E484K; 19:10682606-10682606	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1043A>G; p.K348R; 19:10681104-10681104	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.836T>A; p.L279Q; 19:10679904-10679904	skin	malignant_melanoma	Substitution - Missense
c.579C>T; p.D193D; 19:10678632-10678632	NS	NS	Substitution - coding silent
c.1904C>T; p.P635L; 19:10683688-10683688	skin	malignant_melanoma	Substitution - Missense
c.462G>A; p.A154A; 19:10677213-10677213	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.280C>T; p.R94W; 19:10671404-10671404	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.280C>T; p.R94W; 19:10671404-10671404	urinary_tract; bladder	carcinoma	Substitution - Missense
c.251A>G; p.H84R; 19:10671375-10671375	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.688A>C; p.I230L; 19:10679133-10679133	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1701A>G; p.Q567Q; 19:10683392-10683392	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.518C>T; p.S173F; 19:10677269-10677269	breast	carcinoma	Substitution - Missense
c.2031C>T; p.Y677Y; 19:10683942-10683942	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.56C>A; p.S19Y; 19:10671026-10671026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.713C>G; p.T238S; 19:10679158-10679158	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2042C>T; p.S681L; 19:10683953-10683953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1708G>A; p.G570S; 19:10683399-10683399	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1617C>G; p.L539L; 19:10683205-10683205	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1164G>C; p.K388N; 19:10681313-10681313	breast	carcinoma	Substitution - Missense
c.1727C>T; p.A576V; 19:10683418-10683418	skin	malignant_melanoma	Substitution - Missense
c.1015C>G; p.L339V; 19:10681076-10681076	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.364A>T; p.T122S; 19:10671488-10671488	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.364A>T; p.T122S; 19:10671488-10671488	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2378C>T; p.P793L; 19:10687664-10687664	skin	malignant_melanoma	Substitution - Missense
c.1453G>A; p.E485K; 19:10682609-10682609	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2005G>A; p.G669S; 19:10683789-10683789	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.453C>T; p.D151D; 19:10677204-10677204	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.83T>C; p.L28P; 19:10671053-10671053	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2360C>T; p.S787L; 19:10687646-10687646	urinary_tract; bladder	carcinoma	Substitution - Missense
c.458C>A; p.A153D; 19:10677209-10677209	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1925G>A; p.R642Q; 19:10683709-10683709	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.813C>T; p.A271A; 19:10679881-10679881	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.1477G>A; p.V493M; 19:10682633-10682633	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.188A>G; p.D63G; 19:10671158-10671158	breast	carcinoma	Substitution - Missense
c.718G>A; p.V240M; 19:10679163-10679163	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.718G>A; p.V240M; 19:10679163-10679163	central_nervous_system; brainstem	primitive_neuroectodermal_tumour-medulloblastoma; WNT_subtype	Substitution - Missense
c.718G>A; p.V240M; 19:10679163-10679163	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.377A>T; p.D126V; 19:10671501-10671501	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2400C>A; p.D800E; 19:10687686-10687686	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1439A>G; p.E480G; 19:10682595-10682595	skin	malignant_melanoma	Substitution - Missense
c.1549C>T; p.Q517*; 19:10683137-10683137	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.1677C>T; p.V559V; 19:10683368-10683368	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2241G>C; p.S747S; 19:10687527-10687527	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.139G>A; p.D47N; 19:10671109-10671109	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.2015A>G; p.Y672C; 19:10683926-10683926	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2652C>T; p.N884N; 19:10689279-10689279	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2529C>A; p.G843G; 19:10688656-10688656	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.555T>G; p.A185A; 19:10677306-10677306	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2073C>A; p.S691R; 19:10687359-10687359	liver	carcinoma	Substitution - Missense
c.1997T>C; p.M666T; 19:10683781-10683781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.793C>T; p.P265S; 19:10679861-10679861	skin	malignant_melanoma	Substitution - Missense
c.793C>T; p.P265S; 19:10679861-10679861	skin	malignant_melanoma	Substitution - Missense
c.1381G>T; p.V461L; 19:10682537-10682537	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1623C>T; p.Y541Y; 19:10683211-10683211	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1623C>T; p.Y541Y; 19:10683211-10683211	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1623C>T; p.Y541Y; 19:10683211-10683211	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1767C>T; p.F589F; 19:10683458-10683458	skin	malignant_melanoma	Substitution - coding silent
c.564G>A; p.T188T; 19:10678617-10678617	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1197C>A; p.P399P; 19:10682009-10682009	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.840G>A; p.A280A; 19:10679908-10679908	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1222C>T; p.R408W; 19:10682034-10682034	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.795G>A; p.P265P; 19:10679863-10679863	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2423-9C>A; p.?; 19:10688541-10688541	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1004G>A; p.G335D; 19:10681065-10681065	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.881C>G; p.P294R; 19:10680367-10680367	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1017G>A; p.L339L; 19:10681078-10681078	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2466C>T; p.G822G; 19:10688593-10688593	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2113G>A; p.G705R; 19:10687399-10687399	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.576C>T; p.N192N; 19:10678629-10678629	thyroid	carcinoma	Substitution - coding silent
c.576C>T; p.N192N; 19:10678629-10678629	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.576C>T; p.N192N; 19:10678629-10678629	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.576C>T; p.N192N; 19:10678629-10678629	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2314G>T; p.G772C; 19:10687600-10687600	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2314G>T; p.G772C; 19:10687600-10687600	large_intestine; colon	carcinoma	Substitution - Missense
c.1279G>A; p.V427I; 19:10682091-10682091	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1098C>T; p.A366A; 19:10681247-10681247	skin	malignant_melanoma	Substitution - coding silent
c.2512G>A; p.G838R; 19:10688639-10688639	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1553G>T; p.G518V; 19:10683141-10683141	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.42G>C; p.V14V; 19:10671012-10671012	breast	carcinoma	Substitution - coding silent
c.2591G>A; p.G864D; 19:10689218-10689218	prostate	carcinoma	Substitution - Missense
c.1675-4C>A; p.?; 19:10683362-10683362	liver	carcinoma	Unknown
c.1675-4C>A; p.?; 19:10683362-10683362	liver	carcinoma	Unknown
c.488C>A; p.P163H; 19:10677239-10677239	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1077C>A; p.I359I; 19:10681226-10681226	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2110G>A; p.G704S; 19:10687396-10687396	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.425A>G; p.D142G; 19:10677176-10677176	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2283G>C; p.Q761H; 19:10687569-10687569	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1653C>T; p.H551H; 19:10683241-10683241	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1216C>T; p.L406L; 19:10682028-10682028	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2526C>T; p.G842G; 19:10688653-10688653	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2240C>T; p.S747L; 19:10687526-10687526	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1665C>T; p.F555F; 19:10683253-10683253	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1219A>G; p.M407V; 19:10682031-10682031	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.567A>G; p.L189L; 19:10678620-10678620	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1194_1195insC; p.Q401fs*39; 19:10682006-10682007	ovary	carcinoma; serous_carcinoma	Insertion - Frameshift
c.1455G>A; p.E485E; 19:10682611-10682611	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1850A>T; p.K617M; 19:10683541-10683541	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.781A>G; p.T261A; 19:10679849-10679849	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1609C>T; p.R537C; 19:10683197-10683197	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1609C>T; p.R537C; 19:10683197-10683197	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2398G>A; p.D800N; 19:10687684-10687684	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2398G>A; p.D800N; 19:10687684-10687684	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2398G>A; p.D800N; 19:10687684-10687684	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.109C>G; p.H37D; 19:10671079-10671079	breast	carcinoma	Substitution - Missense
c.1103C>T; p.T368M; 19:10681252-10681252	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.961G>A; p.A321T; 19:10681022-10681022	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.839C>T; p.A280V; 19:10679907-10679907	skin	malignant_melanoma	Substitution - Missense
c.1919G>A; p.R640Q; 19:10683703-10683703	oesophagus	carcinoma	Substitution - Missense
c.665G>A; p.G222E; 19:10679110-10679110	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1803G>C; p.K601N; 19:10683494-10683494	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1509C>T; p.S503S; 19:10682665-10682665	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.560-8_560-7insT; p.?; 19:10678605-10678606	liver	carcinoma	Unknown
c.2033G>T; p.G678V; 19:10683944-10683944	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1905_1906insC; p.N638fs*83; 19:10683689-10683690	breast	carcinoma	Insertion - Frameshift
c.138C>T; p.S46S; 19:10671108-10671108	breast	carcinoma	Substitution - coding silent
c.272G>A; p.G91E; 19:10671396-10671396	pancreas	carcinoma	Substitution - Missense
c.1481C>T; p.A494V; 19:10682637-10682637	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2588C>T; p.S863F; 19:10689215-10689215	skin	malignant_melanoma	Substitution - Missense
c.1269G>A; p.Q423Q; 19:10682081-10682081	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.243G>A; p.K81K; 19:10671367-10671367	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.454G>A; p.D152N; 19:10677205-10677205	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1148C>T; p.P383L; 19:10681297-10681297	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1325C>T; p.S442L; 19:10682137-10682137	skin	malignant_melanoma	Substitution - Missense
c.446C>T; p.S149F; 19:10677197-10677197	breast	carcinoma	Substitution - Missense
c.263C>T; p.T88I; 19:10671387-10671387	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2286C>G; p.S762R; 19:10687572-10687572	ovary	other; neoplasm	Substitution - Missense
c.2124T>G; p.G708G; 19:10687410-10687410	ovary	other; neoplasm	Substitution - coding silent
c.1622A>G; p.Y541C; 19:10683210-10683210	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.960C>T; p.H320H; 19:10681021-10681021	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.960C>T; p.H320H; 19:10681021-10681021	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.950G>A; p.S317N; 19:10680436-10680436	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1281C>G; p.V427V; 19:10682093-10682093	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1555C>T; p.P519S; 19:10683143-10683143	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.246G>A; p.T82T; 19:10671370-10671370	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.245C>T; p.T82M; 19:10671369-10671369	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.245C>T; p.T82M; 19:10671369-10671369	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.245C>T; p.T82M; 19:10671369-10671369	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2231C>G; p.S744C; 19:10687517-10687517	breast	carcinoma	Substitution - Missense
c.983G>A; p.G328D; 19:10681044-10681044	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2212delG; p.G739fs*151; 19:10687498-10687498	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2509G>T; p.G837C; 19:10688636-10688636	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.491C>G; p.P164R; 19:10677242-10677242	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.199G>A; p.V67M; 19:10671169-10671169	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1464G>A; p.A488A; 19:10682620-10682620	breast	carcinoma	Substitution - coding silent
c.2192C>A; p.A731D; 19:10687478-10687478	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2361G>A; p.S787S; 19:10687647-10687647	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.199G>A; p.V67M; 19:10671169-10671169	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.984C>T; p.G328G; 19:10681045-10681045	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]