Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3593

Name

IL12B

Synonymous

interleukin 12B;IL12B;interleukin 12B

Definition

CLMF p40|IL-12 subunit p40|IL12, subunit p40|NK cell stimulatory factor chain 2|cytotoxic lymphocyte maturation factor 40 kDa subunit|interleukin 12, p40|interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2,

Position

5q31.1-q33.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.628G>A; p.V210I; 5:159320375-159320375

 skinmalignant_melanomaSubstitution - Missense

c.823G>A; p.V275I; 5:159318768-159318768

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.922G>A; p.V308M; 5:159316750-159316750

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.862A>G; p.R288G; 5:159316810-159316810

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.69A>T; p.I23I; 5:159326714-159326714

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.204C>A; p.V68V; 5:159323214-159323214

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.96C>G; p.V32V; 5:159323322-159323322

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.872C>T; p.T291M; 5:159316800-159316800

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.873G>T; p.T291T; 5:159316799-159316799

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.24C>A; p.I8I; 5:159326759-159326759

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.874G>T; p.D292Y; 5:159316798-159316798

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.393C>T; p.C131C; 5:159322483-159322483

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.393C>T; p.C131C; 5:159322483-159322483

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.809C>T; p.S270F; 5:159318782-159318782

 skinmalignant_melanomaSubstitution - Missense

c.402G>T; p.K134N; 5:159322474-159322474

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.402G>T; p.K134N; 5:159322474-159322474

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.365-1G>T; p.?; 5:159322512-159322512

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.492C>T; p.D164D; 5:159320511-159320511

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.158C>A; p.P53H; 5:159323260-159323260

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.900C>T; p.C300C; 5:159316772-159316772

 breastcarcinomaSubstitution - coding silent

c.897C>T; p.I299I; 5:159316775-159316775

 skinmalignant_melanomaSubstitution - coding silent

c.826C>G; p.Q276E; 5:159318765-159318765

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.864A>G; p.R288R; 5:159316808-159316808

 stomachadenocarcinomaSubstitution - coding silent

c.60C>T; p.L20L; 5:159326723-159326723

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.810C>T; p.S270S; 5:159318781-159318781

 skinmalignant_melanomaSubstitution - coding silent

c.36C>T; p.S12S; 5:159326747-159326747

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.36C>T; p.S12S; 5:159326747-159326747

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.123C>A; p.A41A; 5:159323295-159323295

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.785G>A; p.W262*; 5:159318806-159318806

 skin; mucosalmalignant_melanomaSubstitution - Nonsense

c.890C>T; p.T297M; 5:159316782-159316782

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.437C>A; p.T146K; 5:159322439-159322439

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.692A>G; p.D231G; 5:159320311-159320311

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.128G>C; p.G43A; 5:159323290-159323290

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.439_440AC>GT; p.T147>?; 5:159322436-159322437

 large_intestine; coloncarcinoma; adenocarcinomaComplex

c.755T>G; p.V252G; 5:159318836-159318836

 breastcarcinomaSubstitution - Missense

c.112T>C; p.Y38H; 5:159323306-159323306

 breastcarcinomaSubstitution - Missense

c.749G>A; p.R250Q; 5:159318842-159318842

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.798T>C; p.H266H; 5:159318793-159318793

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.740A>C; p.K247T; 5:159318851-159318851

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.510C>T; p.C170C; 5:159320493-159320493

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.510C>T; p.C170C; 5:159320493-159320493

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.116C>T; p.P39L; 5:159323302-159323302

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.96C>T; p.V32V; 5:159323322-159323322

 skinmalignant_melanomaSubstitution - coding silent

c.77T>C; p.L26P; 5:159326706-159326706

 central_nervous_system; braingliomaSubstitution - Missense

c.769G>A; p.E257K; 5:159318822-159318822

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.211T>C; p.S71P; 5:159323207-159323207

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.379A>G; p.T127A; 5:159322497-159322497

 breastcarcinomaSubstitution - Missense

c.507G>A; p.T169T; 5:159320496-159320496

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.223C>T; p.L75L; 5:159323195-159323195

 skinmalignant_melanomaSubstitution - coding silent

c.127G>A; p.G43R; 5:159323291-159323291

 skinmalignant_melanomaSubstitution - Missense

c.684C>T; p.F228F; 5:159320319-159320319

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.40G>A; p.V14I; 5:159326743-159326743

 skinmalignant_melanomaSubstitution - Missense

c.117G>A; p.P39P; 5:159323301-159323301

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.982A>T; p.S328C; 5:159316690-159316690

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.415C>T; p.R139C; 5:159322461-159322461

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.204C>T; p.V68V; 5:159323214-159323214

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.241G>C; p.E81Q; 5:159323177-159323177

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.859G>T; p.D287Y; 5:159316813-159316813

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.925C>T; p.R309W; 5:159316747-159316747

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.925C>T; p.R309W; 5:159316747-159316747

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.643G>T; p.V215F; 5:159320360-159320360

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.960C>T; p.S320S; 5:159316712-159316712

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

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