| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3490 |
Name | IGFBP7 |
Synonymous | insulin-like growth factor binding protein 7;IGFBP7;insulin-like growth factor binding protein 7 |
Definition | IGF-binding protein 7|IGFBP-rP1|PGI2-stimulating factor|angiomodulin|insulin-like growth factor-binding protein 7|prostacyclin-stimulating factor|tumor-derived adhesion factor |
Position | 4q12 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.204C>G; p.G68G; 4:57110148-57110148 |
thyroid | other; neoplasm | Substitution - coding silent |
c.204C>G; p.G68G; 4:57110148-57110148 |
thyroid | other; neoplasm | Substitution - coding silent |
c.204C>G; p.G68G; 4:57110148-57110148 |
thyroid | other; neoplasm | Substitution - coding silent |
c.533A>G; p.Y178C; 4:57040876-57040876 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.637C>T; p.R213W; 4:57033260-57033260 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.592delA; p.R198fs*32; 4:57033305-57033305 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.787A>G; p.I263V; 4:57032468-57032468 |
thyroid | carcinoma | Substitution - Missense |
c.568G>C; p.V190L; 4:57040841-57040841 |
liver | carcinoma | Substitution - Missense |
c.730G>T; p.G244*; 4:57032525-57032525 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.568G>C; p.V190L; 4:57040841-57040841 |
liver | carcinoma | Substitution - Missense |
c.830-7delT; p.?; 4:57031343-57031343 |
stomach | carcinoma; diffuse_adenocarcinoma | Unknown |
c.763G>T; p.G255*; 4:57032492-57032492 |
stomach | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.743G>C; p.C248S; 4:57032512-57032512 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.843G>A; p.E281E; 4:57031323-57031323 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.843G>A; p.E281E; 4:57031323-57031323 |
upper_aerodigestive_tract; mouth | carcinoma | Substitution - coding silent |
c.745C>T; p.H249Y; 4:57032510-57032510 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.668G>A; p.G223D; 4:57033229-57033229 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.731G>T; p.G244V; 4:57032524-57032524 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.520G>A; p.G174S; 4:57040889-57040889 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.419C>A; p.A140D; 4:57109933-57109933 |
liver | carcinoma | Substitution - Missense |
c.419C>A; p.A140D; 4:57109933-57109933 |
liver | carcinoma | Substitution - Missense |
c.200A>G; p.E67G; 4:57110152-57110152 |
thyroid | other; neoplasm | Substitution - Missense |
c.200A>G; p.E67G; 4:57110152-57110152 |
thyroid | other; neoplasm | Substitution - Missense |
c.406G>A; p.A136T; 4:57109946-57109946 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.387C>T; p.S129S; 4:57109965-57109965 |
thyroid | carcinoma | Substitution - coding silent |
c.444C>T; p.I148I; 4:57109908-57109908 |
skin | malignant_melanoma | Substitution - coding silent |
c.730G>A; p.G244R; 4:57032525-57032525 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.552C>T; p.I184I; 4:57040857-57040857 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.579G>T; p.W193C; 4:57040830-57040830 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.779C>T; p.S260L; 4:57032476-57032476 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.731G>A; p.G244E; 4:57032524-57032524 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.731G>A; p.G244E; 4:57032524-57032524 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.813A>C; p.E271D; 4:57032442-57032442 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.702+3_702+6delGAGT; p.?; 4:57033189-57033192 |
oesophagus; lower_third | carcinoma; squamous_cell_carcinoma | Unknown |
c.327C>T; p.G109G; 4:57110025-57110025 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.748G>A; p.A250T; 4:57032507-57032507 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.497C>A; p.P166H; 4:57040912-57040912 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.251G>T; p.G84V; 4:57110101-57110101 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.394C>T; p.Q132*; 4:57109958-57109958 |
liver | carcinoma | Substitution - Nonsense |
c.811G>A; p.E271K; 4:57032444-57032444 |
skin | malignant_melanoma | Substitution - Missense |
c.600C>A; p.H200Q; 4:57033297-57033297 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.559C>T; p.P187S; 4:57040850-57040850 |
skin | malignant_melanoma | Substitution - Missense |
c.732A>G; p.G244G; 4:57032523-57032523 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |