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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3484

Name

IGFBP1

Synonymous

insulin-like growth factor binding protein 1;IGFBP1;insulin-like growth factor binding protein 1

Definition

IBP-1|IGF-binding protein 1|IGFBP-1|alpha-pregnancy-associated endometrial globulin|amniotic fluid binding protein|binding protein-25|binding protein-26|binding protein-28|growth hormone independent-binding protein|insulin-like growth factor-binding prote

Position

7p12.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.158G>A; p.R53Q; 7:45888810-45888810

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.312C>G; p.C104W; 7:45888964-45888964

 ovaryother; neoplasmSubstitution - Missense

c.455G>C; p.W152S; 7:45890653-45890653

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.381G>T; p.T127T; 7:45890579-45890579

 skinmalignant_melanomaSubstitution - coding silent

c.519+6G>T; p.?; 7:45890723-45890723

 livercarcinomaUnknown

c.519+6G>T; p.?; 7:45890723-45890723

 livercarcinomaUnknown

c.27C>T; p.V9V; 7:45888679-45888679

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.512A>T; p.K171I; 7:45890710-45890710

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.759A>G; p.I253M; 7:45893070-45893070

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.759A>G; p.I253M; 7:45893070-45893070

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.473A>G; p.Y158C; 7:45890671-45890671

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.102C>T; p.S34S; 7:45888754-45888754

 breastcarcinomaSubstitution - coding silent

c.41T>G; p.L14R; 7:45888693-45888693

 prostateadenomaSubstitution - Missense

c.414C>A; p.F138L; 7:45890612-45890612

 pancreascarcinomaSubstitution - Missense

c.57G>T; p.Q19H; 7:45888709-45888709

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.173G>T; p.G58V; 7:45888825-45888825

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.675G>A; p.A225A; 7:45892986-45892986

 stomachadenocarcinomaSubstitution - coding silent

c.418C>T; p.L140L; 7:45890616-45890616

 skinmalignant_melanomaSubstitution - coding silent

c.549C>T; p.V183V; 7:45891961-45891961

 skinmalignant_melanomaSubstitution - coding silent

c.549C>T; p.V183V; 7:45891961-45891961

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.549C>T; p.V183V; 7:45891961-45891961

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.641G>A; p.S214N; 7:45892053-45892053

 skinmalignant_melanomaSubstitution - Missense

c.460G>A; p.A154T; 7:45890658-45890658

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.592A>C; p.I198L; 7:45892004-45892004

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.575A>G; p.E192G; 7:45891987-45891987

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.756G>C; p.Q252H; 7:45893067-45893067

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.426C>T; p.A142A; 7:45890624-45890624

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.382G>A; p.E128K; 7:45890580-45890580

 skinmalignant_melanomaSubstitution - Missense

c.750C>T; p.N250N; 7:45893061-45893061

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.380C>T; p.T127M; 7:45890578-45890578

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.92C>T; p.A31V; 7:45888744-45888744

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.381G>A; p.T127T; 7:45890579-45890579

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.487G>C; p.A163P; 7:45890685-45890685

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.550G>A; p.V184I; 7:45891962-45891962

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.529C>T; p.R177*; 7:45891941-45891941

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.562G>T; p.A188S; 7:45891974-45891974

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.535G>T; p.E179*; 7:45891947-45891947

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.576G>A; p.E192E; 7:45891988-45891988

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.516G>A; p.W172*; 7:45890714-45890714

 skinmalignant_melanomaSubstitution - Nonsense

c.190G>A; p.A64T; 7:45888842-45888842

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.525C>A; p.P175P; 7:45891937-45891937

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.530G>A; p.R177Q; 7:45891942-45891942

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.530G>A; p.R177Q; 7:45891942-45891942

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.530G>A; p.R177Q; 7:45891942-45891942

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.424G>A; p.A142T; 7:45890622-45890622

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.459C>T; p.D153D; 7:45890657-45890657

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.497T>C; p.V166A; 7:45890695-45890695

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.597C>T; p.S199S; 7:45892009-45892009

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

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