Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3479

Name

IGF1

Synonymous

insulin-like growth factor 1 (somatomedin C);IGF1;insulin-like growth factor 1 (somatomedin C)

Definition

IGF-IA|IGF-IB|MGF|insulin-like growth factor I|insulin-like growth factor IA|insulin-like growth factor IB|mechano growth factor|somatomedin-C

Position

12q23.2

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.456G>C; p.R152S; 12:102402513-102402513

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.48T>G; p.F16L; 12:102480334-102480334

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.86C>T; p.S29F; 12:102475777-102475777

 skinmalignant_melanomaSubstitution - Missense

c.64G>A; p.V22M; 12:102475799-102475799

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.277G>A; p.D93N; 12:102419634-102419634

 skinmalignant_melanomaSubstitution - Missense

c.193G>A; p.V65M; 12:102475670-102475670

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.192C>T; p.F64F; 12:102475671-102475671

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.192C>T; p.F64F; 12:102475671-102475671

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.95T>A; p.L32H; 12:102475768-102475768

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.374G>T; p.R125L; 12:102419537-102419537

 thyroidother; neoplasmSubstitution - Missense

c.212T>G; p.F71C; 12:102475651-102475651

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.317A>T; p.E106V; 12:102419594-102419594

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.327C>T; p.C109C; 12:102419584-102419584

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.402G>A; p.K134K; 12:102419509-102419509

 pancreascarcinomaSubstitution - coding silent

c.157C>T; p.L53F; 12:102475706-102475706

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.167C>A; p.A56D; 12:102475696-102475696

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.293G>A; p.R98Q; 12:102419618-102419618

 skinmalignant_melanomaSubstitution - Missense

c.293G>A; p.R98Q; 12:102419618-102419618

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.293G>A; p.R98Q; 12:102419618-102419618

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.403G>A; p.E135K; 12:102402566-102402566

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.352G>A; p.A118T; 12:102419559-102419559

 skinmalignant_melanomaSubstitution - Missense

c.352G>A; p.A118T; 12:102419559-102419559

 skinmalignant_melanomaSubstitution - Missense

c.364C>T; p.R122C; 12:102419547-102419547

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.361G>T; p.V121F; 12:102419550-102419550

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.347A>C; p.K116T; 12:102419564-102419564

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.373C>T; p.R125C; 12:102419538-102419538

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.394A>G; p.T132A; 12:102419517-102419517

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.199G>A; p.G67R; 12:102475664-102475664

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.462G>T; p.*154Y; 12:102402507-102402507

 lungcarcinoma; adenocarcinomaNonstop extension

c.258G>A; p.A86A; 12:102419653-102419653

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - coding silent

c.64G>T; p.V22L; 12:102475799-102475799

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.129C>T; p.T43T; 12:102475734-102475734

 skinmalignant_melanomaSubstitution - coding silent

c.444C>G; p.N148K; 12:102402525-102402525

 pancreascarcinomaSubstitution - Missense

c.108G>A; p.A36A; 12:102475755-102475755

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.200G>A; p.G67E; 12:102475663-102475663

 skinmalignant_melanomaSubstitution - Missense

c.200G>A; p.G67E; 12:102475663-102475663

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.269G>T; p.G90V; 12:102419642-102419642

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.133T>G; p.S45A; 12:102475730-102475730

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.345delC; p.K116fs*23; 12:102419566-102419566

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.257C>T; p.A86V; 12:102419654-102419654

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.335T>C; p.L112P; 12:102419576-102419576

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.57C>A; p.F19L; 12:102480325-102480325

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.57C>A; p.F19L; 12:102480325-102480325

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

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