| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3014 |
Name | H2AFX |
Synonymous | H2A histone family, member X;H2AFX;H2A histone family, member X |
Definition | H2AX histone|histone H2A.x|histone H2AX |
Position | 11q23.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.29A>G; p.K10R; 11:119095366-119095366 |
oesophagus; lower_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.255G>A; p.Q85Q; 11:119095140-119095140 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.341C>T; p.A114V; 11:119095054-119095054 |
skin | malignant_melanoma | Substitution - Missense |
c.374T>C; p.V125A; 11:119095021-119095021 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.211G>A; p.A71T; 11:119095184-119095184 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.123C>T; p.A41A; 11:119095272-119095272 |
breast | carcinoma | Substitution - coding silent |
c.353C>T; p.P118L; 11:119095042-119095042 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.353C>T; p.P118L; 11:119095042-119095042 |
skin | malignant_melanoma | Substitution - Missense |
c.401A>G; p.K134R; 11:119094994-119094994 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.34C>A; p.R12S; 11:119095361-119095361 |
thyroid | carcinoma | Substitution - Missense |
c.65C>T; p.A22V; 11:119095330-119095330 |
pancreas | carcinoma | Substitution - Missense |
c.322G>T; p.V108F; 11:119095073-119095073 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.407C>T; p.A136V; 11:119094988-119094988 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.296G>T; p.G99V; 11:119095099-119095099 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.124G>A; p.E42K; 11:119095271-119095271 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.124G>A; p.E42K; 11:119095271-119095271 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.412C>A; p.Q138K; 11:119094983-119094983 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.233G>A; p.R78Q; 11:119095162-119095162 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.392C>T; p.S131L; 11:119095003-119095003 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.417C>T; p.A139A; 11:119094978-119094978 |
thyroid | other; neoplasm | Substitution - coding silent |