Entrez Gene

Basic Information
Gene ID	29117
Name	BRD7
Synonymous	bromodomain containing 7;BRD7;bromodomain containing 7
Definition	75 kDa bromodomain protein\|bromodomain-containing protein 7\|protein CELTIX-1
Position	16q12
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1487C>T; p.A496V; 16:50321995-50321995	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1909G>T; p.E637*; 16:50319258-50319258	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.526A>G; p.M176V; 16:50350088-50350088	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1585G>A; p.V529I; 16:50320690-50320690	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.892G>C; p.D298H; 16:50333693-50333693	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.493G>A; p.A165T; 16:50350121-50350121	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.846C>T; p.A282A; 16:50334752-50334752	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.846C>T; p.A282A; 16:50334752-50334752	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1012-1G>C; p.?; 16:50328745-50328745	pancreas	carcinoma	Unknown
c.1867G>A; p.V623I; 16:50319920-50319920	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.399G>C; p.Q133H; 16:50354472-50354472	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.565G>T; p.D189Y; 16:50350049-50350049	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.286C>T; p.R96W; 16:50354895-50354895	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.286C>T; p.R96W; 16:50354895-50354895	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.703-1G>T; p.?; 16:50334896-50334896	prostate	carcinoma; adenocarcinoma	Unknown
c.1381G>C; p.D461H; 16:50323649-50323649	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1923G>A; p.T641T; 16:50319244-50319244	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1339G>T; p.E447*; 16:50323691-50323691	skin	malignant_melanoma	Substitution - Nonsense
c.260A>G; p.E87G; 16:50354921-50354921	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.147C>T; p.F49F; 16:50368201-50368201	skin	malignant_melanoma	Substitution - coding silent
c.1413_1414insG; p.H472fs*14; 16:50323616-50323617	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.398A>G; p.Q133R; 16:50354473-50354473	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1365T>G; p.Y455*; 16:50323665-50323665	liver	carcinoma	Substitution - Nonsense
c.349C>T; p.P117S; 16:50354832-50354832	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.406C>T; p.L136F; 16:50354465-50354465	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1015G>A; p.E339K; 16:50328741-50328741	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.403C>T; p.P135S; 16:50354468-50354468	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1834C>T; p.R612*; 16:50319953-50319953	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1834C>T; p.R612*; 16:50319953-50319953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1834C>T; p.R612*; 16:50319953-50319953	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.745G>C; p.D249H; 16:50334853-50334853	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1352C>A; p.T451K; 16:50323678-50323678	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1834C>T; p.R612*; 16:50319953-50319953	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1656G>A; p.L552L; 16:50320348-50320348	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.963C>T; p.I321I; 16:50333622-50333622	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.591+1G>A; p.?; 16:50350022-50350022	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1366C>T; p.P456S; 16:50323664-50323664	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1873G>A; p.E625K; 16:50319914-50319914	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1922C>T; p.T641M; 16:50319245-50319245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1341G>A; p.E447E; 16:50323689-50323689	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1368delG; p.Y457fs*11; 16:50323662-50323662	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Deletion - Frameshift
c.680C>T; p.S227L; 16:50339998-50339998	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1869C>A; p.V623V; 16:50319918-50319918	breast	carcinoma	Substitution - coding silent
c.422A>G; p.N141S; 16:50354449-50354449	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.846C>G; p.A282A; 16:50334752-50334752	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.831_832insAGAG; p.D278fs*19; 16:50334766-50334767	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.447-1G>T; p.?; 16:50350168-50350168	stomach	carcinoma; adenocarcinoma	Unknown
c.1710G>A; p.P570P; 16:50320294-50320294	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1710G>A; p.P570P; 16:50320294-50320294	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1709C>T; p.P570L; 16:50320295-50320295	skin	malignant_melanoma	Substitution - Missense
c.637C>T; p.P213S; 16:50340041-50340041	skin	malignant_melanoma	Substitution - Missense
c.122G>T; p.S41I; 16:50368226-50368226	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1334T>G; p.I445S; 16:50323696-50323696	breast	carcinoma	Substitution - Missense
c.877G>T; p.E293*; 16:50334721-50334721	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.751C>G; p.Q251E; 16:50334847-50334847	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.751C>G; p.Q251E; 16:50334847-50334847	liver	carcinoma	Substitution - Missense
c.561C>T; p.N187N; 16:50350053-50350053	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1444-4A>G; p.?; 16:50322042-50322042	liver	carcinoma	Unknown
c.1273G>A; p.D425N; 16:50325806-50325806	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1407A>C; p.K469N; 16:50323623-50323623	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1534T>C; p.S512P; 16:50320741-50320741	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.506C>G; p.S169C; 16:50350108-50350108	urinary_tract; bladder	carcinoma	Substitution - Missense
c.274C>T; p.R92*; 16:50354907-50354907	liver	carcinoma	Substitution - Nonsense
c.1563G>T; p.L521L; 16:50320712-50320712	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.274C>T; p.R92*; 16:50354907-50354907	liver	carcinoma	Substitution - Nonsense
c.1843A>G; p.M615V; 16:50319944-50319944	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1381G>A; p.D461N; 16:50323649-50323649	breast	carcinoma	Substitution - Missense
c.869C>T; p.P290L; 16:50334729-50334729	skin	malignant_melanoma	Substitution - Missense
c.712C>T; p.Q238*; 16:50334886-50334886	skin	malignant_melanoma	Substitution - Nonsense
c.1526G>A; p.R509H; 16:50320749-50320749	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.856G>A; p.A286T; 16:50334742-50334742	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1019T>C; p.F340S; 16:50328737-50328737	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1303G>A; p.E435K; 16:50325776-50325776	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.831_832insAG; p.D278fs*35; 16:50334766-50334767	endometrium	carcinoma; endometrioid_carcinoma	Insertion - Frameshift
c.1076C>T; p.P359L; 16:50328680-50328680	skin	malignant_melanoma	Substitution - Missense
c.470C>G; p.S157*; 16:50350144-50350144	liver	carcinoma	Substitution - Nonsense
c.258G>T; p.K86N; 16:50368090-50368090	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Deletion - Frameshift
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	central_nervous_system; brainstem	glioma; astrocytoma_Grade_II	Deletion - Frameshift
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.830_831delAG; p.E277fs*18; 16:50334767-50334768	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.941_942delAG; p.E314fs*5; 16:50333643-50333644	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.19A>G; p.K7E; 16:50368756-50368756	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.329C>T; p.P110L; 16:50354852-50354852	skin	malignant_melanoma	Substitution - Missense
c.325G>A; p.A109T; 16:50354856-50354856	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.151G>T; p.D51Y; 16:50368197-50368197	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1400T>G; p.L467*; 16:50323630-50323630	skin	malignant_melanoma	Substitution - Nonsense
c.632A>G; p.N211S; 16:50340046-50340046	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1346delT; p.L449fs*19; 16:50323684-50323684	liver	carcinoma	Deletion - Frameshift
c.1340A>G; p.E447G; 16:50323690-50323690	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1346delT; p.L449fs*19; 16:50323684-50323684	liver	carcinoma	Deletion - Frameshift
c.199A>G; p.K67E; 16:50368149-50368149	prostate	carcinoma	Substitution - Missense
c.971A>G; p.E324G; 16:50333614-50333614	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.424C>T; p.Q142*; 16:50354447-50354447	skin	malignant_melanoma	Substitution - Nonsense
c.1603G>C; p.D535H; 16:50320672-50320672	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1859C>T; p.P620L; 16:50319928-50319928	skin	malignant_melanoma	Substitution - Missense
c.1859C>T; p.P620L; 16:50319928-50319928	skin	malignant_melanoma	Substitution - Missense
c.774T>G; p.D258E; 16:50334824-50334824	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.718C>G; p.L240V; 16:50334880-50334880	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1536C>T; p.S512S; 16:50320739-50320739	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.1560G>T; p.A520A; 16:50320715-50320715	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.575C>T; p.S192F; 16:50350039-50350039	skin	malignant_melanoma	Substitution - Missense
c.850G>A; p.A284T; 16:50334748-50334748	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1193C>T; p.P398L; 16:50326286-50326286	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1531G>T; p.D511Y; 16:50320744-50320744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1652G>A; p.R551K; 16:50320352-50320352	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.108A>T; p.E36D; 16:50368240-50368240	skin	malignant_melanoma	Substitution - Missense
c.280C>T; p.R94*; 16:50354901-50354901	skin	malignant_melanoma	Substitution - Nonsense
c.1046C>T; p.T349M; 16:50328710-50328710	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.325G>T; p.A109S; 16:50354856-50354856	breast	carcinoma	Substitution - Missense
c.1757-1_1768delGCTGAACAAGTGA; p.?; 16:50320019-50320031	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.682G>C; p.G228R; 16:50339996-50339996	breast	carcinoma	Substitution - Missense
c.130C>A; p.H44N; 16:50368218-50368218	urinary_tract; bladder	carcinoma	Substitution - Missense
c.130C>A; p.H44N; 16:50368218-50368218	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.994C>T; p.R332W; 16:50333591-50333591	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.539C>T; p.T180I; 16:50350075-50350075	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1424C>T; p.T475I; 16:50323606-50323606	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1370A>T; p.Y457F; 16:50323660-50323660	stomach	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]