Entrez Gene

Basic Information
Gene ID	27330
Name	RPS6KA6
Synonymous	ribosomal protein S6 kinase, 90kDa, polypeptide 6;RPS6KA6;ribosomal protein S6 kinase, 90kDa, polypeptide 6
Definition	90 kDa ribosomal protein S6 kinase 6\|RSK-4\|S6K-alpha 6\|S6K-alpha-6\|p90-RSK 6\|p90RSK6\|ribosomal S6 kinase 4\|ribosomal protein S6 kinase alpha-6
Position	Xq21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1552C>T; p.R518W; 23:84104561-84104561	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.649T>G; p.F217V; 23:84120025-84120025	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1552C>T; p.R518W; 23:84104561-84104561	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.924C>T; p.F308F; 23:84117085-84117085	breast	carcinoma	Substitution - coding silent
c.924C>T; p.F308F; 23:84117085-84117085	skin	malignant_melanoma	Substitution - coding silent
c.356G>A; p.R119Q; 23:84147043-84147043	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.265C>T; p.L89F; 23:84148117-84148117	skin	malignant_melanoma	Substitution - Missense
c.1962C>T; p.D654D; 23:84096203-84096203	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.992C>T; p.A331V; 23:84116245-84116245	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1523G>A; p.R508H; 23:84104590-84104590	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.772T>A; p.S258T; 23:84119902-84119902	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.772T>A; p.S258T; 23:84119902-84119902	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1950C>T; p.D650D; 23:84096215-84096215	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.772T>A; p.S258T; 23:84119902-84119902	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.772T>A; p.S258T; 23:84119902-84119902	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.470G>A; p.G157E; 23:84145509-84145509	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1950C>T; p.D650D; 23:84096215-84096215	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.125A>G; p.E42G; 23:84164344-84164344	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1005G>A; p.W335*; 23:84116232-84116232	skin	malignant_melanoma	Substitution - Nonsense
c.2114G>A; p.G705E; 23:84064401-84064401	skin	malignant_melanoma	Substitution - Missense
c.1125G>A; p.L375L; 23:84107027-84107027	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1084C>T; p.P362S; 23:84107650-84107650	skin	malignant_melanoma	Substitution - Missense
c.620A>G; p.D207G; 23:84134808-84134808	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1985A>G; p.H662R; 23:84065098-84065098	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1418G>T; p.R473L; 23:84105824-84105824	liver	carcinoma	Substitution - Missense
c.384G>A; p.V128V; 23:84147015-84147015	skin	malignant_melanoma	Substitution - coding silent
c.1985A>G; p.H662R; 23:84065098-84065098	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.414G>T; p.L138F; 23:84146985-84146985	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.833G>A; p.R278K; 23:84117411-84117411	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2200C>T; p.R734*; 23:84064315-84064315	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1101A>C; p.K367N; 23:84107633-84107633	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1301T>C; p.V434A; 23:84106429-84106429	skin	malignant_melanoma	Substitution - Missense
c.332C>T; p.S111F; 23:84148050-84148050	skin; ear	malignant_melanoma	Substitution - Missense
c.1982C>T; p.S661F; 23:84065101-84065101	skin	malignant_melanoma	Substitution - Missense
c.394C>T; p.H132Y; 23:84147005-84147005	skin	malignant_melanoma	Substitution - Missense
c.1816T>C; p.W606R; 23:84097809-84097809	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.772T>C; p.S258P; 23:84119902-84119902	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.203C>A; p.A68E; 23:84156130-84156130	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.641T>A; p.L214*; 23:84134787-84134787	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.772T>C; p.S258P; 23:84119902-84119902	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1219G>A; p.A407T; 23:84106933-84106933	liver	carcinoma	Substitution - Missense
c.1219G>A; p.A407T; 23:84106933-84106933	liver	carcinoma	Substitution - Missense
c.772T>C; p.S258P; 23:84119902-84119902	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.442C>T; p.L148L; 23:84145537-84145537	skin	malignant_melanoma	Substitution - coding silent
c.2044T>A; p.W682R; 23:84065039-84065039	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1050T>C; p.A350A; 23:84107684-84107684	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1391C>A; p.P464H; 23:84105851-84105851	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1220C>T; p.A407V; 23:84106932-84106932	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1504G>T; p.G502*; 23:84104609-84104609	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.81G>T; p.E27D; 23:84187819-84187819	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.608+1G>T; p.?; 23:84135103-84135103	lung	carcinoma; adenocarcinoma	Unknown
c.743G>T; p.R248I; 23:84119931-84119931	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2233C>T; p.L745L; 23:84064282-84064282	skin	malignant_melanoma	Substitution - coding silent
c.944G>A; p.R315K; 23:84117065-84117065	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2233C>T; p.L745L; 23:84064282-84064282	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1665A>T; p.S555S; 23:84102148-84102148	oesophagus	carcinoma	Substitution - coding silent
c.1721G>A; p.G574E; 23:84102092-84102092	skin	malignant_melanoma	Substitution - Missense
c.790-1delG; p.?; 23:84117455-84117455	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; classic	Unknown
c.1392T>C; p.P464P; 23:84105850-84105850	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1491G>A; p.T497T; 23:84104622-84104622	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1552C>G; p.R518G; 23:84104561-84104561	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1392T>C; p.P464P; 23:84105850-84105850	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1491G>A; p.T497T; 23:84104622-84104622	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.869T>A; p.L290H; 23:84117140-84117140	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1624C>T; p.R542C; 23:84102189-84102189	skin; neck	malignant_melanoma	Substitution - Missense
c.431C>T; p.T144I; 23:84145548-84145548	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2211G>A; p.M737I; 23:84064304-84064304	skin	malignant_melanoma	Substitution - Missense
c.2211G>A; p.M737I; 23:84064304-84064304	skin	malignant_melanoma	Substitution - Missense
c.2014T>C; p.Y672H; 23:84065069-84065069	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1102_1103insA; p.T368fs*3; 23:84107631-84107632	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.383T>A; p.V128E; 23:84147016-84147016	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2161C>T; p.P721S; 23:84064354-84064354	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.468G>A; p.R156R; 23:84145511-84145511	skin	malignant_melanoma	Substitution - coding silent
c.355C>T; p.R119W; 23:84147044-84147044	breast	carcinoma	Substitution - Missense
c.418T>A; p.Y140N; 23:84146981-84146981	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.327_328insA; p.A110fs*36; 23:84148054-84148055	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.688G>A; p.A230T; 23:84119986-84119986	skin	malignant_melanoma	Substitution - Missense
c.907C>A; p.L303I; 23:84117102-84117102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.907C>A; p.L303I; 23:84117102-84117102	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1548G>A; p.S516S; 23:84104565-84104565	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1854-1G>A; p.?; 23:84096312-84096312	stomach	carcinoma; adenocarcinoma	Unknown
c.1103C>A; p.T368K; 23:84107631-84107631	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.441A>T; p.K147N; 23:84145538-84145538	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.324A>C; p.K108N; 23:84148058-84148058	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.194A>T; p.Y65F; 23:84156139-84156139	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.196G>A; p.E66K; 23:84156137-84156137	breast	carcinoma	Substitution - Missense
c.590G>T; p.R197I; 23:84135122-84135122	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2197C>A; p.Q733K; 23:84064318-84064318	breast	carcinoma	Substitution - Missense
c.1362G>A; p.V454V; 23:84106368-84106368	skin	malignant_melanoma	Substitution - coding silent
c.502G>T; p.V168F; 23:84135210-84135210	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1972G>A; p.D658N; 23:84065111-84065111	skin	malignant_melanoma	Substitution - Missense
c.1926C>T; p.F642F; 23:84096239-84096239	skin	malignant_melanoma	Substitution - coding silent
c.1972G>A; p.D658N; 23:84065111-84065111	skin	malignant_melanoma	Substitution - Missense
c.2121G>A; p.M707I; 23:84064394-84064394	skin	malignant_melanoma	Substitution - Missense
c.367G>T; p.E123*; 23:84147032-84147032	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1181C>A; p.S394Y; 23:84106971-84106971	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1181C>A; p.S394Y; 23:84106971-84106971	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1181C>A; p.S394Y; 23:84106971-84106971	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2219G>A; p.R740Q; 23:84064296-84064296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.501+10T>C; p.?; 23:84145468-84145468	pancreas	carcinoma	Unknown
c.1324C>T; p.R442*; 23:84106406-84106406	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2087G>T; p.R696I; 23:84064996-84064996	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1390C>T; p.P464S; 23:84105852-84105852	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1127C>T; p.P376L; 23:84107025-84107025	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.179A>G; p.H60R; 23:84156154-84156154	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1987A>G; p.M663V; 23:84065096-84065096	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.930G>T; p.R310S; 23:84117079-84117079	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1825G>T; p.G609*; 23:84097800-84097800	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.930G>T; p.R310S; 23:84117079-84117079	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1469G>T; p.G490V; 23:84104644-84104644	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.368A>G; p.E123G; 23:84147031-84147031	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1096G>A; p.A366T; 23:84107638-84107638	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1833T>C; p.L611L; 23:84097792-84097792	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.327delA; p.A110fs*3; 23:84148055-84148055	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1907G>T; p.R636L; 23:84096258-84096258	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.833G>T; p.R278I; 23:84117411-84117411	stomach	carcinoma	Substitution - Missense
c.1181C>T; p.S394F; 23:84106971-84106971	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.166C>T; p.P56S; 23:84156167-84156167	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1120G>A; p.G374S; 23:84107032-84107032	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1861C>T; p.P621S; 23:84096304-84096304	skin	malignant_melanoma	Substitution - Missense
c.529T>G; p.F177V; 23:84135183-84135183	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.2002C>A; p.P668T; 23:84065081-84065081	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.333T>C; p.S111S; 23:84148049-84148049	central_nervous_system; brain	glioma	Substitution - coding silent
c.1229delT; p.L410fs*6; 23:84106923-84106923	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1366-1G>T; p.?; 23:84105877-84105877	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1721G>T; p.G574V; 23:84102092-84102092	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1165A>G; p.S389G; 23:84106987-84106987	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.37C>G; p.R13G; 23:84187863-84187863	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1041C>G; p.F347L; 23:84107693-84107693	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2045G>T; p.W682L; 23:84065038-84065038	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1906C>T; p.R636C; 23:84096259-84096259	NS	NS	Substitution - Missense
c.2141T>C; p.L714P; 23:84064374-84064374	central_nervous_system; brain	glioma	Substitution - Missense
c.950G>A; p.G317E; 23:84116287-84116287	skin	malignant_melanoma	Substitution - Missense
c.1652A>G; p.Y551C; 23:84102161-84102161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1054G>A; p.G352R; 23:84107680-84107680	skin; scalp	malignant_melanoma	Substitution - Missense
c.1882G>T; p.D628Y; 23:84096283-84096283	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.165C>T; p.I55I; 23:84156168-84156168	skin	malignant_melanoma	Substitution - coding silent
c.1115C>A; p.S372Y; 23:84107037-84107037	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.254G>A; p.G85E; 23:84156079-84156079	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.990_991insT; p.A331fs*4; 23:84116246-84116247	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.115G>A; p.E39K; 23:84164354-84164354	skin	malignant_melanoma	Substitution - Missense
c.1948G>T; p.D650Y; 23:84096217-84096217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1339A>G; p.T447A; 23:84106391-84106391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1472G>C; p.R491T; 23:84104641-84104641	oesophagus	carcinoma	Substitution - Missense
c.2081C>A; p.P694Q; 23:84065002-84065002	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1342A>G; p.T448A; 23:84106388-84106388	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1735C>G; p.L579V; 23:84102078-84102078	oesophagus	carcinoma	Substitution - Missense
c.979C>T; p.H327Y; 23:84116258-84116258	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.419A>G; p.Y140C; 23:84146980-84146980	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.419A>G; p.Y140C; 23:84146980-84146980	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.1328G>A; p.C443Y; 23:84106402-84106402	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.118G>T; p.E40*; 23:84164351-84164351	ovary	other; neoplasm	Substitution - Nonsense
c.40G>A; p.E14K; 23:84187860-84187860	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1502A>C; p.K501T; 23:84104611-84104611	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1923A>G; p.K641K; 23:84096242-84096242	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1465G>T; p.D489Y; 23:84104648-84104648	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1183A>G; p.I395V; 23:84106969-84106969	breast	carcinoma	Substitution - Missense
c.68C>T; p.A23V; 23:84187832-84187832	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1368C>T; p.I456I; 23:84105874-84105874	skin	malignant_melanoma	Substitution - coding silent
c.1744C>T; p.P582S; 23:84102069-84102069	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1833T>A; p.L611L; 23:84097792-84097792	breast	carcinoma	Substitution - coding silent
c.1798G>A; p.D600N; 23:84097827-84097827	skin	malignant_melanoma	Substitution - Missense
c.798G>T; p.M266I; 23:84117446-84117446	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.121_122GG>AA; p.G41K; 23:84164347-84164348	skin	malignant_melanoma	Substitution - Missense
c.1739T>A; p.L580*; 23:84102074-84102074	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1711C>A; p.Q571K; 23:84102102-84102102	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.929G>T; p.R310M; 23:84117080-84117080	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.130G>T; p.D44Y; 23:84164339-84164339	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2068C>T; p.P690S; 23:84065015-84065015	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.570C>T; p.H190H; 23:84135142-84135142	skin	malignant_melanoma	Substitution - coding silent
c.771G>T; p.W257C; 23:84119903-84119903	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.141+3A>G; p.?; 23:84164325-84164325	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.2112G>T; p.K704N; 23:84064971-84064971	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1926C>A; p.F642L; 23:84096239-84096239	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.438G>A; p.G146G; 23:84145541-84145541	skin	malignant_melanoma	Substitution - coding silent
c.438G>A; p.G146G; 23:84145541-84145541	skin	malignant_melanoma	Substitution - coding silent
c.438G>A; p.G146G; 23:84145541-84145541	skin	malignant_melanoma	Substitution - coding silent
c.438G>A; p.G146G; 23:84145541-84145541	skin	malignant_melanoma	Substitution - coding silent
c.1152C>G; p.L384L; 23:84107000-84107000	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.518A>G; p.E173G; 23:84135194-84135194	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1815C>A; p.I605I; 23:84097810-84097810	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2203C>T; p.R735W; 23:84064312-84064312	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1757C>A; p.A586E; 23:84102056-84102056	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1368C>A; p.I456I; 23:84105874-84105874	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.790-2A>T; p.?; 23:84117456-84117456	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1085C>T; p.P362L; 23:84107649-84107649	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.325A>G; p.K109E; 23:84148057-84148057	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1003T>G; p.W335G; 23:84116234-84116234	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.340+1G>A; p.?; 23:84148041-84148041	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.398C>A; p.P133Q; 23:84147001-84147001	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1325G>A; p.R442Q; 23:84106405-84106405	urinary_tract; bladder	carcinoma	Substitution - Missense
c.779G>C; p.G260A; 23:84119895-84119895	skin	malignant_melanoma	Substitution - Missense
c.662A>G; p.K221R; 23:84120012-84120012	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1831C>T; p.L611F; 23:84097794-84097794	skin	malignant_melanoma	Substitution - Missense
c.837T>A; p.N279K; 23:84117407-84117407	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.837T>A; p.N279K; 23:84117407-84117407	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1299T>C; p.G433G; 23:84106431-84106431	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1777-2A>G; p.?; 23:84097850-84097850	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.480T>G; p.V160V; 23:84145499-84145499	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1076G>C; p.C359S; 23:84107658-84107658	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.855A>T; p.I285I; 23:84117389-84117389	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.644C>T; p.T215I; 23:84134784-84134784	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.695C>T; p.S232L; 23:84119979-84119979	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.684G>T; p.K228N; 23:84119990-84119990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1908T>C; p.R636R; 23:84096257-84096257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.629G>T; p.G210V; 23:84134799-84134799	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1048G>T; p.A350S; 23:84107686-84107686	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1808G>A; p.C603Y; 23:84097817-84097817	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.66C>T; p.G22G; 23:84187834-84187834	liver	carcinoma	Substitution - coding silent
c.1417C>T; p.R473C; 23:84105825-84105825	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.66C>T; p.G22G; 23:84187834-84187834	liver	carcinoma	Substitution - coding silent
c.2064G>C; p.Q688H; 23:84065019-84065019	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1513T>C; p.L505L; 23:84104600-84104600	skin	malignant_melanoma	Substitution - coding silent
c.156T>A; p.V52V; 23:84156177-84156177	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.686A>C; p.K229T; 23:84119988-84119988	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.352G>T; p.V118F; 23:84147047-84147047	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.298C>A; p.Q100K; 23:84148084-84148084	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.869T>C; p.L290P; 23:84117140-84117140	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]