Entrez Gene

Basic Information
Gene ID	27327
Name	TNRC6A
Synonymous	trinucleotide repeat containing 6A;TNRC6A;trinucleotide repeat containing 6A
Definition	CAG repeat protein 26\|EDIE\|EMSY interactor protein\|GW182 autoantigen\|glycine-tryptophan protein of 182 kDa\|trinucleotide repeat-containing gene 6A protein
Position	16p11.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2231G>A; p.R744Q; 16:24790873-24790873	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5816G>T; p.G1939V; 16:24823734-24823734	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1358C>G; p.P453R; 16:24790000-24790000	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.5848C>A; p.L1950I; 16:24823766-24823766	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3388G>A; p.D1130N; 16:24794579-24794579	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5848C>A; p.L1950I; 16:24823766-24823766	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3739A>G; p.N1247D; 16:24804221-24804221	pancreas	carcinoma	Substitution - Missense
c.503T>G; p.V168G; 16:24777272-24777272	breast	carcinoma	Substitution - Missense
c.3739A>G; p.N1247D; 16:24804221-24804221	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.3678G>C; p.K1226N; 16:24797950-24797950	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4953_4954CC>TT; p.L1652F; 16:24816937-24816938	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3928C>G; p.Q1310E; 16:24804795-24804795	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1975C>G; p.Q659E; 16:24790617-24790617	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1854C>A; p.N618K; 16:24790496-24790496	breast	carcinoma	Substitution - Missense
c.4837C>T; p.R1613C; 16:24816821-24816821	skin	malignant_melanoma	Substitution - Missense
c.4837C>T; p.R1613C; 16:24816821-24816821	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4646C>A; p.S1549Y; 16:24809455-24809455	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3785G>A; p.R1262Q; 16:24804267-24804267	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2792C>T; p.S931F; 16:24791434-24791434	skin	malignant_melanoma	Substitution - Missense
c.4910T>A; p.V1637D; 16:24816894-24816894	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5449G>A; p.G1817R; 16:24822949-24822949	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.416G>T; p.R139L; 16:24777185-24777185	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2294C>T; p.A765V; 16:24790936-24790936	liver	carcinoma	Substitution - Missense
c.2516delG; p.G840fs*63; 16:24791158-24791158	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4308C>T; p.N1436N; 16:24806262-24806262	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2402_2403insG; p.W804fs*4; 16:24791044-24791045	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4832-4C>G; p.?; 16:24816812-24816812	liver	carcinoma	Unknown
c.4832-4C>G; p.?; 16:24816812-24816812	liver	carcinoma	Unknown
c.3166A>T; p.S1056C; 16:24791808-24791808	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2516delG; p.G840fs*63; 16:24791158-24791158	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.840A>G; p.K280K; 16:24789482-24789482	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3541delA; p.R1183fs*7; 16:24795919-24795919	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4273A>G; p.R1425G; 16:24806227-24806227	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3541delA; p.R1183fs*7; 16:24795919-24795919	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2350G>T; p.G784C; 16:24790992-24790992	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3974C>A; p.S1325Y; 16:24804841-24804841	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5029C>T; p.R1677C; 16:24818649-24818649	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3223G>T; p.D1075Y; 16:24793520-24793520	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.4285C>T; p.Q1429*; 16:24806239-24806239	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.1192A>G; p.I398V; 16:24789834-24789834	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5029C>T; p.R1677C; 16:24818649-24818649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2684C>A; p.S895Y; 16:24791326-24791326	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1712G>A; p.G571D; 16:24790354-24790354	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4871T>C; p.I1624T; 16:24816855-24816855	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3207T>C; p.T1069T; 16:24793504-24793504	thyroid	other; neoplasm	Substitution - coding silent
c.1990G>C; p.A664P; 16:24790632-24790632	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.829G>A; p.G277S; 16:24789471-24789471	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3866A>G; p.N1289S; 16:24804733-24804733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1792C>T; p.R598*; 16:24790434-24790434	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4312C>T; p.P1438S; 16:24806266-24806266	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5393G>T; p.R1798L; 16:24822893-24822893	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.415C>T; p.R139*; 16:24777184-24777184	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.114G>T; p.K38N; 16:24750786-24750786	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4861T>C; p.Y1621H; 16:24816845-24816845	pancreas	carcinoma	Substitution - Missense
c.4861T>C; p.Y1621H; 16:24816845-24816845	pancreas	carcinoma	Substitution - Missense
c.732C>T; p.G244G; 16:24789374-24789374	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3981A>T; p.R1327S; 16:24804848-24804848	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4861T>C; p.Y1621H; 16:24816845-24816845	pancreas	carcinoma	Substitution - Missense
c.5554A>T; p.S1852C; 16:24823472-24823472	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5376C>T; p.I1792I; 16:24822876-24822876	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2903C>A; p.T968K; 16:24791545-24791545	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1429A>G; p.S477G; 16:24790071-24790071	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2071C>T; p.Q691*; 16:24790713-24790713	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2260G>A; p.G754R; 16:24790902-24790902	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2452C>T; p.Q818*; 16:24791094-24791094	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.352_366del15; p.Q121_Q125delQPQQQ; 16:24777121-24777135	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Deletion - In frame
c.4718C>T; p.P1573L; 16:24815192-24815192	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.3290C>T; p.A1097V; 16:24793587-24793587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5806G>A; p.D1936N; 16:24823724-24823724	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2362C>T; p.P788S; 16:24791004-24791004	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3762G>A; p.T1254T; 16:24804244-24804244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4940G>T; p.R1647L; 16:24816924-24816924	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1200G>A; p.Q400Q; 16:24789842-24789842	oesophagus	carcinoma	Substitution - coding silent
c.5810C>A; p.P1937H; 16:24823728-24823728	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.5111C>T; p.S1704F; 16:24820169-24820169	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.5810C>A; p.P1937H; 16:24823728-24823728	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1566G>A; p.W522*; 16:24790208-24790208	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2403delG; p.W804fs*99; 16:24791045-24791045	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3596C>T; p.A1199V; 16:24797524-24797524	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 16:24797524-24797524	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3596C>T; p.A1199V; 16:24797524-24797524	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3182G>T; p.G1061V; 16:24793479-24793479	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2828C>T; p.S943F; 16:24791470-24791470	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2684C>T; p.S895F; 16:24791326-24791326	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5637G>A; p.Q1879Q; 16:24823555-24823555	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.5637G>A; p.Q1879Q; 16:24823555-24823555	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.4288A>G; p.R1430G; 16:24806242-24806242	skin	malignant_melanoma	Substitution - Missense
c.4087C>T; p.R1363C; 16:24805116-24805116	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1558A>G; p.T520A; 16:24790200-24790200	pancreas	carcinoma	Substitution - Missense
c.1558A>G; p.T520A; 16:24790200-24790200	pancreas	carcinoma	Substitution - Missense
c.1558A>G; p.T520A; 16:24790200-24790200	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2656G>A; p.G886S; 16:24791298-24791298	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1558A>G; p.T520A; 16:24790200-24790200	central_nervous_system; thalamus	glioma; astrocytoma_Grade_III	Substitution - Missense
c.1166C>A; p.S389Y; 16:24789808-24789808	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.354G>T; p.Q118H; 16:24777123-24777123	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4123-9G>T; p.?; 16:24805596-24805596	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.5120C>A; p.S1707*; 16:24820178-24820178	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3500C>T; p.P1167L; 16:24794691-24794691	liver	carcinoma	Substitution - Missense
c.5120C>A; p.S1707*; 16:24820178-24820178	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.351G>A; p.P117P; 16:24777120-24777120	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2043C>T; p.R681R; 16:24790685-24790685	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3004G>A; p.D1002N; 16:24791646-24791646	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5620_5621delTC; p.L1875fs*34; 16:24823538-24823539	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1450C>T; p.R484C; 16:24790092-24790092	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4636G>A; p.V1546M; 16:24809445-24809445	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5682G>T; p.R1894R; 16:24823600-24823600	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3821A>G; p.N1274S; 16:24804303-24804303	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3442G>C; p.E1148Q; 16:24794633-24794633	central_nervous_system; brainstem	glioma; astrocytoma_Grade_III	Substitution - Missense
c.3791A>G; p.Q1264R; 16:24804273-24804273	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2930C>T; p.A977V; 16:24791572-24791572	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2714A>G; p.N905S; 16:24791356-24791356	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.104A>C; p.K35T; 16:24750776-24750776	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4739G>A; p.S1580N; 16:24815213-24815213	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.4152A>C; p.P1384P; 16:24805634-24805634	thyroid	other; neoplasm	Substitution - coding silent
c.3517A>G; p.M1173V; 16:24794708-24794708	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5651C>T; p.S1884F; 16:24823569-24823569	skin	malignant_melanoma	Substitution - Missense
c.391C>T; p.R131W; 16:24777160-24777160	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5371C>G; p.Q1791E; 16:24822145-24822145	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5047G>A; p.V1683I; 16:24818667-24818667	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3019G>C; p.A1007P; 16:24791661-24791661	central_nervous_system; brain	glioma	Substitution - Missense
c.5779A>G; p.S1927G; 16:24823697-24823697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4414C>T; p.P1472S; 16:24806658-24806658	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.530C>G; p.A177G; 16:24777299-24777299	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1583A>G; p.N528S; 16:24790225-24790225	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3291G>T; p.A1097A; 16:24793588-24793588	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5456C>T; p.A1819V; 16:24822956-24822956	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.724G>A; p.A242T; 16:24789366-24789366	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2344G>A; p.G782R; 16:24790986-24790986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.936A>G; p.P312P; 16:24789578-24789578	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2572G>C; p.G858R; 16:24791214-24791214	ovary	other; neoplasm	Substitution - Missense
c.350C>A; p.P117Q; 16:24777119-24777119	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2936C>T; p.A979V; 16:24791578-24791578	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4294G>A; p.V1432M; 16:24806248-24806248	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1550C>G; p.S517C; 16:24790192-24790192	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.P183S; 16:24777316-24777316	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1563A>C; p.T521T; 16:24790205-24790205	breast	carcinoma	Substitution - coding silent
c.1450C>A; p.R484S; 16:24790092-24790092	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1609C>T; p.P537S; 16:24790251-24790251	skin	malignant_melanoma	Substitution - Missense
c.304C>T; p.Q102*; 16:24777073-24777073	breast	carcinoma	Substitution - Nonsense
c.1476G>T; p.Q492H; 16:24790118-24790118	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4314G>A; p.P1438P; 16:24806268-24806268	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5552C>T; p.A1851V; 16:24823470-24823470	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.792_793delAG; p.R266fs*13; 16:24789434-24789435	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.20A>G; p.K7R; 16:24730267-24730267	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.4169A>T; p.N1390I; 16:24805651-24805651	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4277C>T; p.A1426V; 16:24806231-24806231	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3713G>A; p.R1238Q; 16:24804195-24804195	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4774G>C; p.D1592H; 16:24815248-24815248	oesophagus	carcinoma	Substitution - Missense
c.1040C>G; p.T347S; 16:24789682-24789682	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2024G>A; p.S675N; 16:24790666-24790666	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1970A>T; p.N657I; 16:24790612-24790612	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1358C>A; p.P453Q; 16:24790000-24790000	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.438A>C; p.K146N; 16:24777207-24777207	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5015C>T; p.A1672V; 16:24818635-24818635	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1719G>T; p.V573V; 16:24790361-24790361	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5258G>A; p.R1753H; 16:24820316-24820316	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2820A>T; p.P940P; 16:24791462-24791462	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.555T>A; p.N185K; 16:24777324-24777324	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1509C>T; p.S503S; 16:24790151-24790151	skin	malignant_melanoma	Substitution - coding silent
c.5794C>G; p.P1932A; 16:24823712-24823712	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3985-1G>T; p.?; 16:24805013-24805013	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.3410G>T; p.R1137L; 16:24794601-24794601	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3353-10C>G; p.?; 16:24794534-24794534	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.5272T>A; p.W1758R; 16:24820330-24820330	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3279A>C; p.E1093D; 16:24793576-24793576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5350G>A; p.V1784I; 16:24822124-24822124	breast	carcinoma	Substitution - Missense
c.416G>A; p.R139Q; 16:24777185-24777185	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4174C>G; p.L1392V; 16:24805656-24805656	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.416G>A; p.R139Q; 16:24777185-24777185	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2984T>C; p.I995T; 16:24791626-24791626	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2911C>T; p.L971L; 16:24791553-24791553	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4002G>A; p.M1334I; 16:24805031-24805031	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5384C>T; p.S1795L; 16:24822884-24822884	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3018A>C; p.S1006S; 16:24791660-24791660	central_nervous_system; brain	glioma	Substitution - coding silent
c.891T>A; p.V297V; 16:24789533-24789533	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.5203C>A; p.P1735T; 16:24820261-24820261	skin	malignant_melanoma	Substitution - Missense
c.3066G>T; p.W1022C; 16:24791708-24791708	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.108C>T; p.D36D; 16:24750780-24750780	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.500A>C; p.K167T; 16:24777269-24777269	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1401C>T; p.S467S; 16:24790043-24790043	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.558C>T; p.N186N; 16:24777327-24777327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2324A>C; p.N775T; 16:24790966-24790966	liver	carcinoma	Substitution - Missense
c.2495C>T; p.S832L; 16:24791137-24791137	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4372C>T; p.R1458C; 16:24806616-24806616	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4372C>T; p.R1458C; 16:24806616-24806616	central_nervous_system; brain	glioma	Substitution - Missense
c.4721A>T; p.Y1574F; 16:24815195-24815195	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2990G>T; p.R997L; 16:24791632-24791632	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3066G>A; p.W1022*; 16:24791708-24791708	skin	malignant_melanoma	Substitution - Nonsense
c.824A>C; p.N275T; 16:24789466-24789466	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4808C>G; p.S1603C; 16:24815282-24815282	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4588G>A; p.E1530K; 16:24809397-24809397	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.344C>A; p.P115Q; 16:24777113-24777113	thyroid	other; neoplasm	Substitution - Missense
c.344C>A; p.P115Q; 16:24777113-24777113	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4570G>A; p.D1524N; 16:24809379-24809379	breast	carcinoma	Substitution - Missense
c.344C>A; p.P115Q; 16:24777113-24777113	thyroid	other; neoplasm	Substitution - Missense
c.2304T>C; p.D768D; 16:24790946-24790946	central_nervous_system; brain	glioma	Substitution - coding silent
c.344C>A; p.P115Q; 16:24777113-24777113	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4513A>G; p.I1505V; 16:24806757-24806757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2472G>C; p.E824D; 16:24791114-24791114	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4120C>T; p.Q1374*; 16:24805149-24805149	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.3881C>T; p.S1294F; 16:24804748-24804748	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.494C>A; p.A165D; 16:24777263-24777263	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.311C>T; p.P104L; 16:24777080-24777080	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.169G>C; p.E57Q; 16:24776938-24776938	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.311C>A; p.P104Q; 16:24777080-24777080	liver	carcinoma	Substitution - Missense
c.311C>A; p.P104Q; 16:24777080-24777080	liver	carcinoma	Substitution - Missense
c.2302G>T; p.D768Y; 16:24790944-24790944	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4327C>T; p.Q1443*; 16:24806281-24806281	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3513G>T; p.K1171N; 16:24794704-24794704	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4986C>T; p.S1662S; 16:24818606-24818606	skin	malignant_melanoma	Substitution - coding silent
c.4293C>T; p.S1431S; 16:24806247-24806247	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4293C>T; p.S1431S; 16:24806247-24806247	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1075A>T; p.S359C; 16:24789717-24789717	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3597G>A; p.A1199A; 16:24797525-24797525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2989C>T; p.R997C; 16:24791631-24791631	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3317C>G; p.S1106C; 16:24793614-24793614	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2336C>T; p.S779F; 16:24790978-24790978	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4314G>T; p.P1438P; 16:24806268-24806268	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.1122G>A; p.E374E; 16:24789764-24789764	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4786C>T; p.R1596C; 16:24815260-24815260	central_nervous_system; brain	glioma	Substitution - Missense
c.5247T>A; p.N1749K; 16:24820305-24820305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.288G>T; p.Q96H; 16:24777057-24777057	central_nervous_system; brain	glioma	Substitution - Missense
c.1135G>C; p.A379P; 16:24789777-24789777	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.1211A>G; p.N404S; 16:24789853-24789853	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4203G>A; p.L1401L; 16:24805685-24805685	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.4746A>C; p.S1582S; 16:24815220-24815220	thyroid	other; neoplasm	Substitution - coding silent
c.4746A>C; p.S1582S; 16:24815220-24815220	thyroid	other; neoplasm	Substitution - coding silent
c.2545T>G; p.W849G; 16:24791187-24791187	breast	carcinoma	Substitution - Missense
c.4368A>G; p.Q1456Q; 16:24806612-24806612	breast	carcinoma	Substitution - coding silent
c.5572C>T; p.R1858C; 16:24823490-24823490	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4851A>G; p.P1617P; 16:24816835-24816835	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1383C>A; p.T461T; 16:24790025-24790025	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.298C>A; p.Q100K; 16:24777067-24777067	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.506T>C; p.L169S; 16:24777275-24777275	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4770A>G; p.I1590M; 16:24815244-24815244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.186T>C; p.S62S; 16:24776955-24776955	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.5885T>G; p.M1962R; 16:24823803-24823803	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1004C>T; p.S335F; 16:24789646-24789646	urinary_tract; bladder	carcinoma	Substitution - Missense
c.5766G>A; p.P1922P; 16:24823684-24823684	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4286A>G; p.Q1429R; 16:24806240-24806240	skin	malignant_melanoma	Substitution - Missense
c.5631C>T; p.S1877S; 16:24823549-24823549	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.355_366del12; p.Q124_Q127delQQPQ; 16:24777124-24777135	liver	carcinoma	Deletion - In frame
c.335_338delAGCC; p.Q112fs*37; 16:24777104-24777107	skin	malignant_melanoma	Deletion - Frameshift
c.1125C>T; p.N375N; 16:24789767-24789767	breast	carcinoma	Substitution - coding silent
c.5412C>T; p.H1804H; 16:24822912-24822912	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5412C>T; p.H1804H; 16:24822912-24822912	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5412C>T; p.H1804H; 16:24822912-24822912	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5412C>T; p.H1804H; 16:24822912-24822912	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5412C>T; p.H1804H; 16:24822912-24822912	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5412C>T; p.H1804H; 16:24822912-24822912	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5274G>A; p.W1758*; 16:24820332-24820332	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.478G>A; p.A160T; 16:24777247-24777247	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4771G>T; p.G1591*; 16:24815245-24815245	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.5782C>T; p.L1928L; 16:24823700-24823700	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3110C>T; p.A1037V; 16:24791752-24791752	liver	carcinoma	Substitution - Missense
c.3110C>T; p.A1037V; 16:24791752-24791752	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2929G>T; p.A977S; 16:24791571-24791571	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1204C>T; p.P402S; 16:24789846-24789846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3095G>A; p.R1032H; 16:24791737-24791737	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2410T>G; p.W804G; 16:24791052-24791052	breast	carcinoma	Substitution - Missense
c.3561G>T; p.R1187S; 16:24795939-24795939	liver	carcinoma	Substitution - Missense
c.2597G>T; p.W866L; 16:24791239-24791239	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5591A>G; p.Q1864R; 16:24823509-24823509	eye; uveal_tract	malignant_melanoma; epithelioid	Substitution - Missense
c.5430C>T; p.F1810F; 16:24822930-24822930	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4196C>T; p.A1399V; 16:24805678-24805678	skin	malignant_melanoma	Substitution - Missense
c.459G>T; p.Q153H; 16:24777228-24777228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5220G>T; p.Q1740H; 16:24820278-24820278	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2153T>A; p.L718Q; 16:24790795-24790795	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4877C>A; p.P1626H; 16:24816861-24816861	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.37G>T; p.E13*; 16:24730284-24730284	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2810C>T; p.S937L; 16:24791452-24791452	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5509C>T; p.H1837Y; 16:24823009-24823009	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2810C>T; p.S937L; 16:24791452-24791452	breast	carcinoma	Substitution - Missense
c.5509C>T; p.H1837Y; 16:24823009-24823009	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.421C>T; p.R141C; 16:24777190-24777190	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2309C>T; p.T770I; 16:24790951-24790951	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4796C>T; p.S1599L; 16:24815270-24815270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4796C>T; p.S1599L; 16:24815270-24815270	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2897C>A; p.P966H; 16:24791539-24791539	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3715A>G; p.M1239V; 16:24804197-24804197	liver	carcinoma	Substitution - Missense
c.3715A>G; p.M1239V; 16:24804197-24804197	liver	carcinoma	Substitution - Missense
c.5299C>T; p.P1767S; 16:24820357-24820357	breast	carcinoma	Substitution - Missense
c.3076G>A; p.V1026I; 16:24791718-24791718	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1241G>T; p.G414V; 16:24789883-24789883	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3076G>A; p.V1026I; 16:24791718-24791718	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3309G>A; p.T1103T; 16:24793606-24793606	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4355A>T; p.Q1452L; 16:24806599-24806599	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.5051C>T; p.P1684L; 16:24818671-24818671	liver	carcinoma	Substitution - Missense
c.1219A>G; p.I407V; 16:24789861-24789861	liver	carcinoma	Substitution - Missense
c.1219A>G; p.I407V; 16:24789861-24789861	liver	carcinoma	Substitution - Missense
c.1842C>T; p.S614S; 16:24790484-24790484	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.5016C>A; p.A1672A; 16:24818636-24818636	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1188T>C; p.S396S; 16:24789830-24789830	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4998G>A; p.T1666T; 16:24818618-24818618	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.851G>A; p.R284Q; 16:24789493-24789493	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2231G>T; p.R744L; 16:24790873-24790873	liver	carcinoma	Substitution - Missense
c.2939_2941delAAG; p.E983delE; 16:24791581-24791583	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.2227G>A; p.E743K; 16:24790869-24790869	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3757C>T; p.R1253*; 16:24804239-24804239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1146G>A; p.G382G; 16:24789788-24789788	soft_tissue; striated_muscle	rhabdoid_tumour	Substitution - coding silent
c.1178T>G; p.I393S; 16:24789820-24789820	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1774G>A; p.A592T; 16:24790416-24790416	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5625C>T; p.L1875L; 16:24823543-24823543	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.93G>T; p.K31N; 16:24750765-24750765	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5226A>C; p.P1742P; 16:24820284-24820284	breast	carcinoma	Substitution - coding silent
c.5274G>T; p.W1758C; 16:24820332-24820332	breast	carcinoma	Substitution - Missense
c.5286C>T; p.D1762D; 16:24820344-24820344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.317A>C; p.Q106P; 16:24777086-24777086	liver	carcinoma	Substitution - Missense
c.2169G>T; p.W723C; 16:24790811-24790811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.305A>C; p.Q102P; 16:24777074-24777074	pancreas	carcinoma	Substitution - Missense
c.1502G>T; p.G501V; 16:24790144-24790144	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4333C>T; p.R1445*; 16:24806577-24806577	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.317A>C; p.Q106P; 16:24777086-24777086	liver	carcinoma	Substitution - Missense
c.5594C>T; p.S1865F; 16:24823512-24823512	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3435G>T; p.E1145D; 16:24794626-24794626	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5197_5198CC>TT; p.P1733L; 16:24820255-24820256	skin	malignant_melanoma	Substitution - Missense
c.1072C>T; p.P358S; 16:24789714-24789714	skin	malignant_melanoma	Substitution - Missense
c.1072C>T; p.P358S; 16:24789714-24789714	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4394T>C; p.L1465S; 16:24806638-24806638	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3418G>T; p.G1140C; 16:24794609-24794609	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3176-2A>G; p.?; 16:24793471-24793471	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.289C>T; p.Q97*; 16:24777058-24777058	central_nervous_system; brain	glioma	Substitution - Nonsense
c.2607C>T; p.A869A; 16:24791249-24791249	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3200C>T; p.P1067L; 16:24793497-24793497	skin	malignant_melanoma	Substitution - Missense
c.4744T>C; p.S1582P; 16:24815218-24815218	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.779C>G; p.S260C; 16:24789421-24789421	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2444A>G; p.K815R; 16:24791086-24791086	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2972C>A; p.S991Y; 16:24791614-24791614	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1996A>G; p.T666A; 16:24790638-24790638	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5762C>T; p.T1921I; 16:24823680-24823680	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3065_3066GG>TT; p.W1022F; 16:24791707-24791708	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.895A>G; p.S299G; 16:24789537-24789537	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1049C>A; p.S350Y; 16:24789691-24789691	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3057G>A; p.V1019V; 16:24791699-24791699	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.4405C>T; p.Q1469*; 16:24806649-24806649	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.2710C>T; p.P904S; 16:24791352-24791352	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1135G>T; p.A379S; 16:24789777-24789777	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.257A>G; p.K86R; 16:24777026-24777026	urinary_tract; bladder	carcinoma	Substitution - Missense
c.408A>G; p.V136V; 16:24777177-24777177	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3223G>C; p.D1075H; 16:24793520-24793520	breast	carcinoma	Substitution - Missense
c.468T>A; p.P156P; 16:24777237-24777237	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2752C>A; p.P918T; 16:24791394-24791394	skin	malignant_melanoma	Substitution - Missense
c.514C>G; p.Q172E; 16:24777283-24777283	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5686G>A; p.D1896N; 16:24823604-24823604	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]