Entrez Gene

Basic Information
Gene ID	27000
Name	DNAJC2
Synonymous	DnaJ (Hsp40) homolog, subfamily C, member 2;DNAJC2;DnaJ (Hsp40) homolog, subfamily C, member 2
Definition	M-phase phosphoprotein 11\|dnaJ homolog subfamily C member 2\|zuotin related factor 1\|zuotin-related factor 1
Position	7q22
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1070_1071delTC; p.L357fs*21; 7:103319654-103319655	breast	carcinoma	Deletion - Frameshift
c.77G>A; p.C26Y; 7:103341942-103341942	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1660T>C; p.Y554H; 7:103312952-103312952	liver	carcinoma	Substitution - Missense
c.1660T>C; p.Y554H; 7:103312952-103312952	liver	carcinoma	Substitution - Missense
c.1601G>T; p.R534I; 7:103313011-103313011	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.590_591insA; p.N197fs*4; 7:103324544-103324545	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1405C>T; p.P469S; 7:103315869-103315869	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.711A>G; p.K237K; 7:103323606-103323606	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1169G>A; p.R390H; 7:103316962-103316962	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.310C>T; p.Q104*; 7:103337757-103337757	pancreas	carcinoma	Substitution - Nonsense
c.214G>C; p.E72Q; 7:103341805-103341805	breast	carcinoma	Substitution - Missense
c.1406C>T; p.P469L; 7:103315868-103315868	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.238G>C; p.D80H; 7:103341781-103341781	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.472A>T; p.N158Y; 7:103326643-103326643	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.916G>A; p.A306T; 7:103321973-103321973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1083A>T; p.T361T; 7:103319642-103319642	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.346T>G; p.L116V; 7:103327740-103327740	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1234T>C; p.W412R; 7:103316897-103316897	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1491G>A; p.T497T; 7:103315783-103315783	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.590delA; p.N197fs*8; 7:103324545-103324545	skin	malignant_melanoma	Deletion - Frameshift
c.590delA; p.N197fs*8; 7:103324545-103324545	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.590delA; p.N197fs*8; 7:103324545-103324545	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.590delA; p.N197fs*8; 7:103324545-103324545	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1749G>C; p.K583N; 7:103312575-103312575	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1445A>T; p.K482M; 7:103315829-103315829	skin	malignant_melanoma	Substitution - Missense
c.829G>T; p.A277S; 7:103322060-103322060	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.348A>G; p.L116L; 7:103327738-103327738	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.549C>A; p.T183T; 7:103326566-103326566	ovary	other; neoplasm	Substitution - coding silent
c.549C>A; p.T183T; 7:103326566-103326566	ovary	other; neoplasm	Substitution - coding silent
c.680T>G; p.F227C; 7:103323637-103323637	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1256T>A; p.L419*; 7:103316875-103316875	liver	carcinoma	Substitution - Nonsense
c.1256T>A; p.L419*; 7:103316875-103316875	liver	carcinoma	Substitution - Nonsense
c.1622C>T; p.A541V; 7:103312990-103312990	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1485C>T; p.N495N; 7:103315789-103315789	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1287T>C; p.A429A; 7:103316844-103316844	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.833C>T; p.A278V; 7:103322056-103322056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1500A>G; p.E500E; 7:103315774-103315774	skin	malignant_melanoma	Substitution - coding silent
c.915delA; p.A306fs*29; 7:103321974-103321974	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.943C>T; p.R315*; 7:103321946-103321946	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1211G>T; p.G404V; 7:103316920-103316920	breast	carcinoma	Substitution - Missense
c.131_132delGA; p.R44fs*12; 7:103341887-103341888	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.308C>A; p.T103K; 7:103337759-103337759	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1689C>T; p.V563V; 7:103312635-103312635	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1597G>A; p.E533K; 7:103313015-103313015	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1689C>T; p.V563V; 7:103312635-103312635	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1152A>C; p.K384N; 7:103316979-103316979	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1416A>G; p.K472K; 7:103315858-103315858	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.406G>C; p.D136H; 7:103327680-103327680	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1009G>T; p.E337*; 7:103319793-103319793	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.87A>G; p.E29E; 7:103341932-103341932	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.557T>G; p.F186C; 7:103326558-103326558	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.869G>A; p.R290K; 7:103322020-103322020	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.408C>G; p.D136E; 7:103327678-103327678	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1507G>C; p.E503Q; 7:103315767-103315767	breast	carcinoma	Substitution - Missense
c.738G>T; p.W246C; 7:103322776-103322776	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.503T>C; p.V168A; 7:103326612-103326612	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.417T>C; p.T139T; 7:103327669-103327669	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1749G>T; p.K583N; 7:103312575-103312575	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.668C>A; p.S223Y; 7:103323649-103323649	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.647C>A; p.S216Y; 7:103324488-103324488	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1189A>G; p.N397D; 7:103316942-103316942	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.562A>C; p.R188R; 7:103326553-103326553	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1533T>C; p.P511P; 7:103313079-103313079	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1533T>C; p.P511P; 7:103313079-103313079	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.538G>A; p.E180K; 7:103326577-103326577	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.980A>T; p.N327I; 7:103319822-103319822	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1223G>A; p.G408E; 7:103316908-103316908	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1197G>C; p.E399D; 7:103316934-103316934	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.534C>T; p.F178F; 7:103326581-103326581	skin	malignant_melanoma	Substitution - coding silent
c.1125A>T; p.E375D; 7:103317006-103317006	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.160G>A; p.E54K; 7:103341859-103341859	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.915_916insA; p.A306fs*3; 7:103321973-103321974	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.537C>T; p.F179F; 7:103326578-103326578	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.537C>T; p.F179F; 7:103326578-103326578	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1657C>T; p.R553*; 7:103312955-103312955	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1455A>G; p.K485K; 7:103315819-103315819	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1102G>A; p.A368T; 7:103319623-103319623	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.39C>T; p.T13T; 7:103344584-103344584	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1286C>A; p.A429D; 7:103316845-103316845	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.49C>T; p.H17Y; 7:103344574-103344574	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.419G>A; p.C140Y; 7:103327667-103327667	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.499T>C; p.S167P; 7:103326616-103326616	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1260A>G; p.L420L; 7:103316871-103316871	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1216G>A; p.G406R; 7:103316915-103316915	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Substitution - Missense
c.1613T>C; p.I538T; 7:103312999-103312999	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.784G>A; p.E262K; 7:103322730-103322730	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1627C>T; p.P543S; 7:103312985-103312985	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.442T>G; p.L148V; 7:103326673-103326673	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.223A>G; p.M75V; 7:103341796-103341796	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1142G>T; p.R381I; 7:103316989-103316989	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]