Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2539

Name

G6PD

Synonymous

glucose-6-phosphate dehydrogenase;G6PD;glucose-6-phosphate dehydrogenase

Definition

glucose-6-phosphate 1-dehydrogenase

Position

Xq28

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1527G>A; p.W509*; 23:154532021-154532021

 breastcarcinomaSubstitution - Nonsense

c.1178G>A; p.R393H; 23:154532676-154532676

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.386A>C; p.H129P; 23:154535267-154535267

 breastcarcinomaSubstitution - Missense

c.539C>T; p.S180F; 23:154534443-154534443

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.737G>A; p.R246H; 23:154534068-154534068

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1390A>G; p.I464V; 23:154532255-154532255

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1254G>A; p.S418S; 23:154532600-154532600

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1254G>A; p.S418S; 23:154532600-154532600

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1082C>T; p.A361V; 23:154532772-154532772

 breastcarcinomaSubstitution - Missense

c.1179C>T; p.R393R; 23:154532675-154532675

 central_nervous_system; braingliomaSubstitution - coding silent

c.1534C>A; p.P512T; 23:154532014-154532014

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.934C>T; p.P312S; 23:154533059-154533059

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1149G>T; p.Q383H; 23:154532705-154532705

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1221G>C; p.K407N; 23:154532633-154532633

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1178G>T; p.R393L; 23:154532676-154532676

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.585G>T; p.Q195H; 23:154534397-154534397

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.526G>A; p.D176N; 23:154534456-154534456

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1424A>G; p.E475G; 23:154532221-154532221

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.574C>T; p.R192C; 23:154534408-154534408

 skinmalignant_melanomaSubstitution - Missense

c.574C>T; p.R192C; 23:154534408-154534408

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.717G>C; p.E239D; 23:154534088-154534088

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.777G>C; p.V259V; 23:154533663-154533663

 parathyroidcarcinomaSubstitution - coding silent

c.114T>G; p.G38G; 23:154546042-154546042

 skinmalignant_melanomaSubstitution - coding silent

c.829G>A; p.A277T; 23:154533611-154533611

 central_nervous_system; braingliomaSubstitution - Missense

c.1246G>A; p.E416K; 23:154532608-154532608

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.972C>T; p.D324D; 23:154533021-154533021

 livercarcinomaSubstitution - coding silent

c.972C>T; p.D324D; 23:154533021-154533021

 livercarcinomaSubstitution - coding silent

c.972C>T; p.D324D; 23:154533021-154533021

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.771-10C>T; p.?; 23:154533679-154533679

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.1310A>T; p.Y437F; 23:154532440-154532440

 skinmalignant_melanomaSubstitution - Missense

c.521G>A; p.G174E; 23:154534461-154534461

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.202G>A; p.V68M; 23:154536002-154536002

 breastcarcinomaSubstitution - Missense

c.672C>A; p.I224I; 23:154534133-154534133

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1215G>A; p.M405I; 23:154532639-154532639

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.334T>C; p.Y112H; 23:154535319-154535319

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1229G>A; p.G410D; 23:154532625-154532625

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.1000delA; p.T334fs*29; 23:154532993-154532993

 central_nervous_system; brainglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.1535C>A; p.P512H; 23:154532013-154532013

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1535C>A; p.P512H; 23:154532013-154532013

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.977C>T; p.P326L; 23:154533016-154533016

 skinmalignant_melanomaSubstitution - Missense

c.691G>A; p.A231T; 23:154534114-154534114

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.446C>T; p.A149V; 23:154535207-154535207

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1002C>T; p.T334T; 23:154532991-154532991

 oesophaguscarcinomaSubstitution - coding silent

c.366C>A; p.N122K; 23:154535287-154535287

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1501T>C; p.F501L; 23:154532047-154532047

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1269C>T; p.T423T; 23:154532585-154532585

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.936C>T; p.P312P; 23:154533057-154533057

 skinmalignant_melanomaSubstitution - coding silent

c.1534C>T; p.P512S; 23:154532014-154532014

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.697G>A; p.V233I; 23:154534108-154534108

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.751G>A; p.D251N; 23:154534054-154534054

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1102G>A; p.E368K; 23:154532752-154532752

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.750C>T; p.F250F; 23:154534055-154534055

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.750C>T; p.F250F; 23:154534055-154534055

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1021G>A; p.V341I; 23:154532972-154532972

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.990C>T; p.R330R; 23:154533003-154533003

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1013C>T; p.A338V; 23:154532980-154532980

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1013C>T; p.A338V; 23:154532980-154532980

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1093C>T; p.R365C; 23:154532761-154532761

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.754G>C; p.E252Q; 23:154534051-154534051

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.937G>A; p.D313N; 23:154533056-154533056

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.212C>T; p.A71V; 23:154535992-154535992

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.654C>T; p.N218N; 23:154534151-154534151

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.187G>A; p.E63K; 23:154536017-154536017

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.429C>G; p.P143P; 23:154535224-154535224

 thyroidcarcinomaSubstitution - coding silent

c.1203C>T; p.Y401Y; 23:154532651-154532651

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1441C>T; p.P481S; 23:154532204-154532204

 skinmalignant_melanomaSubstitution - Missense

c.775G>A; p.V259M; 23:154533665-154533665

 breastcarcinomaSubstitution - Missense

c.1397C>G; p.T466S; 23:154532248-154532248

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.856G>C; p.D286H; 23:154533584-154533584

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.746A>G; p.Y249C; 23:154534059-154534059

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.480C>A; p.S160R; 23:154535173-154535173

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.473G>T; p.C158F; 23:154535180-154535180

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.563C>T; p.S188F; 23:154534419-154534419

 central_nervous_system; braingliomaSubstitution - Missense

c.736C>T; p.R246C; 23:154534069-154534069

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.78C>A; p.F26L; 23:154546078-154546078

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1273G>A; p.G425S; 23:154532581-154532581

 pancreascarcinomaSubstitution - Missense

c.973G>T; p.D325Y; 23:154533020-154533020

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.538T>C; p.S180P; 23:154534444-154534444

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.811G>A; p.V271M; 23:154533629-154533629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1503C>G; p.F501L; 23:154532045-154532045

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

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