Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

246175

Name

CNOT6L

Synonymous

CCR4-NOT transcription complex, subunit 6-like;CNOT6L;CCR4-NOT transcription complex, subunit 6-like

Definition

CCR4-NOT transcription complex subunit 6-like|carbon catabolite repressor protein 4 homolog B

Position

4q13.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1698A>C; p.E566D; 4:77720488-77720488

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.300T>C; p.I100I; 4:77774631-77774631

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1153G>C; p.V385L; 4:77729040-77729040

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.599C>T; p.P200L; 4:77748363-77748363

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.299T>C; p.I100T; 4:77774632-77774632

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.800T>C; p.L267P; 4:77744722-77744722

 skinmalignant_melanomaSubstitution - Missense

c.1069G>A; p.V357I; 4:77731429-77731429

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.15C>T; p.R5R; 4:77819381-77819381

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.913G>A; p.E305K; 4:77742187-77742187

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.691G>A; p.A231T; 4:77744831-77744831

 central_nervous_system; braingliomaSubstitution - Missense

c.1156G>A; p.A386T; 4:77729037-77729037

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.860G>T; p.G287V; 4:77742240-77742240

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1156G>A; p.A386T; 4:77729037-77729037

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.328C>T; p.L110L; 4:77774603-77774603

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1207C>T; p.Q403*; 4:77728986-77728986

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.857G>A; p.R286H; 4:77742243-77742243

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.1700T>C; p.L567P; 4:77720486-77720486

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.717C>T; p.C239C; 4:77744805-77744805

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1713C>T; p.L571L; 4:77720473-77720473

 skinmalignant_melanomaSubstitution - coding silent

c.1543G>C; p.G515R; 4:77720643-77720643

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.1167C>A; p.H389Q; 4:77729026-77729026

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1083A>C; p.L361F; 4:77731415-77731415

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1070T>C; p.V357A; 4:77731428-77731428

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.739G>A; p.E247K; 4:77744783-77744783

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1071C>T; p.V357V; 4:77731427-77731427

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.600G>A; p.P200P; 4:77748362-77748362

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.658G>T; p.V220F; 4:77744864-77744864

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.893C>T; p.A298V; 4:77742207-77742207

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.455G>A; p.R152Q; 4:77773113-77773113

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.246G>T; p.W82C; 4:77774685-77774685

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.125C>T; p.P42L; 4:77776360-77776360

 skinmalignant_melanomaSubstitution - Missense

c.118T>G; p.Y40D; 4:77776367-77776367

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.1338A>G; p.S446S; 4:77728855-77728855

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1446T>A; p.N482K; 4:77726263-77726263

 skinmalignant_melanomaSubstitution - Missense

c.1411G>A; p.E471K; 4:77726298-77726298

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.574G>A; p.A192T; 4:77756865-77756865

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.801T>C; p.L267L; 4:77744721-77744721

 pancreascarcinomaSubstitution - coding silent

c.1447G>T; p.G483*; 4:77726262-77726262

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1615_1616delCA; p.Q539fs*4; 4:77720570-77720571

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - Frameshift

c.877delT; p.S293fs*17; 4:77742223-77742223

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.1004C>T; p.A335V; 4:77731494-77731494

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1004C>T; p.A335V; 4:77731494-77731494

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1663C>T; p.P555S; 4:77720523-77720523

 skinmalignant_melanomaSubstitution - Missense

c.808G>T; p.V270L; 4:77742292-77742292

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.808G>T; p.V270L; 4:77742292-77742292

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1613C>T; p.P538L; 4:77720573-77720573

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1231G>A; p.V411I; 4:77728962-77728962

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.1153G>A; p.V385M; 4:77729040-77729040

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1231G>A; p.V411I; 4:77728962-77728962

 pancreascarcinomaSubstitution - Missense

c.504G>A; p.Q168Q; 4:77756935-77756935

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.950A>G; p.K317R; 4:77742150-77742150

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.542G>A; p.R181Q; 4:77756897-77756897

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.542G>A; p.R181Q; 4:77756897-77756897

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1026C>T; p.S342S; 4:77731472-77731472

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.596C>T; p.P199L; 4:77748366-77748366

 skinmalignant_melanomaSubstitution - Missense

c.1151T>C; p.I384T; 4:77729042-77729042

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.1342G>A; p.V448I; 4:77726367-77726367

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

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