Entrez Gene

Basic Information
Gene ID	23368
Name	PPP1R13B
Synonymous	protein phosphatase 1, regulatory subunit 13B;PPP1R13B;protein phosphatase 1, regulatory subunit 13B
Definition	apoptosis-stimulating of p53 protein 1\|apoptosis-stimulating protein of p53, 1\|protein phosphatase 1 regulatory subunit 13B\|protein phosphatase 1, regulatory (inhibitor) subunit 13B
Position	14q32.33
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.189C>T; p.Y63Y; 14:103784883-103784883	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.550G>T; p.E184*; 14:103754151-103754151	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.832C>T; p.R278C; 14:103749931-103749931	skin	malignant_melanoma	Substitution - Missense
c.580C>T; p.R194C; 14:103754121-103754121	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.580C>T; p.R194C; 14:103754121-103754121	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1923T>A; p.P641P; 14:103740493-103740493	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1511C>T; p.P504L; 14:103742101-103742101	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1105T>C; p.S369P; 14:103746418-103746418	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.493C>T; p.R165C; 14:103754208-103754208	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1121C>T; p.S374L; 14:103746402-103746402	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.433C>T; p.Q145*; 14:103757673-103757673	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1433_1434CC>TT; p.S478F; 14:103742178-103742179	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1051C>T; p.Q351*; 14:103746472-103746472	skin	malignant_melanoma	Substitution - Nonsense
c.2638C>T; p.H880Y; 14:103738978-103738978	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1743C>T; p.S581S; 14:103741869-103741869	skin	malignant_melanoma	Substitution - coding silent
c.3012G>C; p.Q1004H; 14:103737713-103737713	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.3012G>C; p.Q1004H; 14:103737713-103737713	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2477C>T; p.T826M; 14:103739939-103739939	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.85C>T; p.R29*; 14:103797443-103797443	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2397C>T; p.P799P; 14:103740019-103740019	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.408T>G; p.A136A; 14:103757698-103757698	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1152T>C; p.A384A; 14:103742822-103742822	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3268G>A; p.A1090T; 14:103735159-103735159	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.792G>A; p.A264A; 14:103753036-103753036	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1498C>A; p.P500T; 14:103742114-103742114	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2240C>T; p.P747L; 14:103740176-103740176	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2356G>T; p.A786S; 14:103740060-103740060	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1986C>T; p.T662T; 14:103740430-103740430	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2103G>A; p.A701A; 14:103740313-103740313	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1972G>A; p.A658T; 14:103740444-103740444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1592C>T; p.P531L; 14:103742020-103742020	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2101G>A; p.A701T; 14:103740315-103740315	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1899G>A; p.T633T; 14:103740517-103740517	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.545G>A; p.R182Q; 14:103754156-103754156	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2757C>T; p.D919D; 14:103738786-103738786	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.238C>T; p.L80F; 14:103784834-103784834	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2002C>T; p.R668W; 14:103740414-103740414	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.613A>G; p.I205V; 14:103754088-103754088	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.613A>G; p.I205V; 14:103754088-103754088	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2360C>T; p.P787L; 14:103740056-103740056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1425G>A; p.S475S; 14:103742187-103742187	skin	malignant_melanoma	Substitution - coding silent
c.2129C>T; p.S710F; 14:103740287-103740287	skin	malignant_melanoma	Substitution - Missense
c.2448G>A; p.P816P; 14:103739968-103739968	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.809G>C; p.R270T; 14:103753019-103753019	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2538G>T; p.E846D; 14:103739878-103739878	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.61C>T; p.P21S; 14:103797467-103797467	skin	malignant_melanoma	Substitution - Missense
c.1149C>T; p.S383S; 14:103746374-103746374	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1450G>A; p.E484K; 14:103742162-103742162	skin	malignant_melanoma	Substitution - Missense
c.1160G>C; p.G387A; 14:103742814-103742814	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.940C>T; p.R314C; 14:103749823-103749823	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.940C>T; p.R314C; 14:103749823-103749823	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.286C>T; p.Q96*; 14:103778813-103778813	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1487G>T; p.S496I; 14:103742125-103742125	thyroid	other; neoplasm	Substitution - Missense
c.10A>T; p.M4L; 14:103797518-103797518	breast	carcinoma	Substitution - Missense
c.3260G>A; p.R1087Q; 14:103735167-103735167	skin	malignant_melanoma	Substitution - Missense
c.1589A>C; p.Y530S; 14:103742023-103742023	ovary	other; neoplasm	Substitution - Missense
c.116G>A; p.G39E; 14:103797412-103797412	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2652C>T; p.V884V; 14:103738964-103738964	pancreas	carcinoma	Substitution - coding silent
c.3132C>T; p.D1044D; 14:103736102-103736102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3132C>T; p.D1044D; 14:103736102-103736102	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.855A>C; p.Q285H; 14:103749908-103749908	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2916G>T; p.Q972H; 14:103737809-103737809	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2776C>T; p.H926Y; 14:103738767-103738767	liver	carcinoma	Substitution - Missense
c.1965C>T; p.A655A; 14:103740451-103740451	skin	malignant_melanoma	Substitution - coding silent
c.247G>A; p.E83K; 14:103784825-103784825	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1885G>T; p.G629W; 14:103740531-103740531	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.400A>G; p.M134V; 14:103757706-103757706	thyroid	carcinoma	Substitution - Missense
c.365C>A; p.P122Q; 14:103757741-103757741	breast	carcinoma	Substitution - Missense
c.925C>T; p.R309*; 14:103749838-103749838	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1969C>T; p.P657S; 14:103740447-103740447	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1673C>T; p.A558V; 14:103741939-103741939	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1673C>T; p.A558V; 14:103741939-103741939	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3118T>G; p.F1040V; 14:103736116-103736116	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2316C>G; p.L772L; 14:103740100-103740100	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.220G>A; p.E74K; 14:103784852-103784852	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.698_699insT; p.L233fs*4; 14:103753129-103753130	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.220G>A; p.E74K; 14:103784852-103784852	liver	carcinoma	Substitution - Missense
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1531delC; p.Q511fs*39; 14:103742081-103742081	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1600G>A; p.G534R; 14:103742012-103742012	skin	malignant_melanoma	Substitution - Missense
c.896G>A; p.R299H; 14:103749867-103749867	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.190G>A; p.E64K; 14:103784882-103784882	skin	malignant_melanoma	Substitution - Missense
c.2367A>T; p.S789S; 14:103740049-103740049	liver	carcinoma	Substitution - coding silent
c.2367A>T; p.S789S; 14:103740049-103740049	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.2367A>T; p.S789S; 14:103740049-103740049	liver	carcinoma	Substitution - coding silent
c.1099C>T; p.P367S; 14:103746424-103746424	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3194G>A; p.G1065E; 14:103736040-103736040	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.390G>A; p.E130E; 14:103757716-103757716	kidney	other; neoplasm	Substitution - coding silent
c.2218A>G; p.T740A; 14:103740198-103740198	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2562_2563CC>TT; p.P855S; 14:103739853-103739854	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1710A>T; p.G570G; 14:103741902-103741902	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.311G>T; p.R104I; 14:103778788-103778788	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2415C>T; p.I805I; 14:103740001-103740001	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1182G>T; p.Q394H; 14:103742792-103742792	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.967C>T; p.Q323*; 14:103749796-103749796	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1457G>C; p.S486T; 14:103742155-103742155	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3213G>A; p.V1071V; 14:103736021-103736021	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2663C>A; p.P888H; 14:103738953-103738953	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2663C>A; p.P888H; 14:103738953-103738953	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.302G>A; p.R101Q; 14:103778797-103778797	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1682G>T; p.G561V; 14:103741930-103741930	breast	carcinoma	Substitution - Missense
c.302G>A; p.R101Q; 14:103778797-103778797	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2470G>A; p.V824M; 14:103739946-103739946	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2624C>T; p.S875L; 14:103738992-103738992	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2346C>T; p.P782P; 14:103740070-103740070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1962C>T; p.P654P; 14:103740454-103740454	skin	malignant_melanoma	Substitution - coding silent
c.1773G>T; p.K591N; 14:103741839-103741839	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.347A>C; p.E116A; 14:103778752-103778752	skin	malignant_melanoma	Substitution - Missense
c.3251C>T; p.P1084L; 14:103735176-103735176	pancreas	carcinoma	Substitution - Missense
c.1685C>G; p.S562*; 14:103741927-103741927	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2457C>T; p.D819D; 14:103739959-103739959	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.183G>C; p.M61I; 14:103784889-103784889	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.742G>A; p.G248R; 14:103753086-103753086	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.663C>A; p.F221L; 14:103753165-103753165	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3051T>C; p.G1017G; 14:103736183-103736183	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2685G>A; p.A895A; 14:103738931-103738931	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.782C>T; p.T261M; 14:103753046-103753046	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.464G>A; p.R155H; 14:103754237-103754237	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2640C>T; p.H880H; 14:103738976-103738976	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.301C>T; p.R101*; 14:103778798-103778798	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.301C>T; p.R101*; 14:103778798-103778798	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3070G>A; p.A1024T; 14:103736164-103736164	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.45G>A; p.Q15Q; 14:103797483-103797483	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.457-2A>T; p.?; 14:103754246-103754246	lung	carcinoma; adenocarcinoma	Unknown
c.190G>T; p.E64*; 14:103784882-103784882	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2578C>T; p.P860S; 14:103739838-103739838	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.241C>T; p.R81*; 14:103784831-103784831	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1066G>A; p.G356R; 14:103746457-103746457	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1066G>A; p.G356R; 14:103746457-103746457	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2103G>T; p.A701A; 14:103740313-103740313	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1229G>A; p.W410*; 14:103742745-103742745	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2397delC; p.E800fs*71; 14:103740019-103740019	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2023C>T; p.L675F; 14:103740393-103740393	skin	malignant_melanoma	Substitution - Missense
c.1900G>C; p.G634R; 14:103740516-103740516	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2741C>A; p.P914H; 14:103738802-103738802	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.563A>T; p.N188I; 14:103754138-103754138	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.2442C>A; p.A814A; 14:103739974-103739974	skin	malignant_melanoma	Substitution - coding silent
c.3254G>A; p.R1085Q; 14:103735173-103735173	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2102C>T; p.A701V; 14:103740314-103740314	breast	carcinoma	Substitution - Missense
c.2102C>T; p.A701V; 14:103740314-103740314	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2563_2564CC>TT; p.P855F; 14:103739852-103739853	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.171C>G; p.P57P; 14:103784901-103784901	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1243G>A; p.V415M; 14:103742731-103742731	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2137G>A; p.E713K; 14:103740279-103740279	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2393delC; p.E800fs*71; 14:103740023-103740023	large_intestine; colon	carcinoma	Deletion - Frameshift
c.2947T>G; p.S983A; 14:103737778-103737778	stomach	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]