Entrez Gene

Basic Information
Gene ID	23353
Name	SUN1
Synonymous	Sad1 and UNC84 domain containing 1;SUN1;Sad1 and UNC84 domain containing 1
Definition	SUN domain-containing protein 1\|Sad1 unc-84 domain protein 1\|protein unc-84 homolog A\|sad1/unc-84 protein-like 1\|unc-84 homolog A
Position	7p22.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.509-2A>T; p.?; 7:851948-851948	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.610C>T; p.R204*; 7:852616-852616	pancreas	carcinoma	Substitution - Nonsense
c.610C>T; p.R204*; 7:852616-852616	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.376G>A; p.A126T; 7:843388-843388	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.677G>A; p.R226Q; 7:852825-852825	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.358G>T; p.G120W; 7:843370-843370	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.778A>G; p.T260A; 7:852926-852926	liver	carcinoma	Substitution - Missense
c.1890C>T; p.F630F; 7:869507-869507	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.776C>T; p.T259M; 7:852924-852924	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.762C>T; p.D254D; 7:852910-852910	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.456C>T; p.P152P; 7:843468-843468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.651C>T; p.F217F; 7:852657-852657	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1275+8T>G; p.?; 7:857965-857965	liver	carcinoma	Unknown
c.1275+8T>G; p.?; 7:857965-857965	liver	carcinoma	Unknown
c.1847C>T; p.T616M; 7:869464-869464	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1350G>T; p.L450L; 7:860202-860202	bone	chondrosarcoma	Substitution - coding silent
c.2005G>A; p.D669N; 7:873227-873227	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.488C>G; p.S163C; 7:843500-843500	urinary_tract; bladder	carcinoma	Substitution - Missense
c.472G>A; p.V158M; 7:843484-843484	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.556C>A; p.Q186K; 7:851997-851997	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.556C>A; p.Q186K; 7:851997-851997	large_intestine; colon	carcinoma	Substitution - Missense
c.307G>T; p.D103Y; 7:843211-843211	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.470C>T; p.P157L; 7:843482-843482	skin	malignant_melanoma	Substitution - Missense
c.1071T>A; p.D357E; 7:854976-854976	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.239G>A; p.R80Q; 7:842068-842068	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.470C>T; p.P157L; 7:843482-843482	skin	malignant_melanoma	Substitution - Missense
c.1071T>A; p.D357E; 7:854976-854976	stomach	adenocarcinoma	Substitution - Missense
c.397T>G; p.F133V; 7:843409-843409	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1755C>T; p.C585C; 7:869372-869372	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1258G>A; p.D420N; 7:857940-857940	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.698C>T; p.S233L; 7:852846-852846	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.384C>T; p.T128T; 7:843396-843396	stomach	adenocarcinoma	Substitution - coding silent
c.461C>T; p.A154V; 7:843473-843473	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.395G>A; p.G132D; 7:843407-843407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.395G>A; p.G132D; 7:843407-843407	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1443C>A; p.H481Q; 7:860295-860295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1452C>T; p.S484S; 7:860304-860304	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1452C>T; p.S484S; 7:860304-860304	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.397delT; p.F133fs*58; 7:843409-843409	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.1977G>A; p.Q659Q; 7:872547-872547	NS	NS	Substitution - coding silent
c.1666G>A; p.A556T; 7:866002-866002	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1453G>A; p.V485M; 7:860305-860305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1331G>T; p.G444V; 7:860183-860183	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.734G>T; p.R245I; 7:852882-852882	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1117C>G; p.L373V; 7:856373-856373	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1529C>T; p.A510V; 7:860381-860381	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1173A>G; p.T391T; 7:857855-857855	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1173A>G; p.T391T; 7:857855-857855	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.349C>G; p.Q117E; 7:843361-843361	breast	carcinoma	Substitution - Missense
c.1654G>A; p.E552K; 7:865990-865990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1654G>A; p.E552K; 7:865990-865990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.823_824CC>TT; p.P275L; 7:853427-853428	skin	malignant_melanoma	Substitution - Missense
c.823_824CC>TT; p.P275L; 7:853427-853428	skin	malignant_melanoma	Substitution - Missense
c.1586G>T; p.G529V; 7:861435-861435	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.575C>A; p.S192Y; 7:852016-852016	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1319A>G; p.E440G; 7:860171-860171	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.936T>C; p.A312A; 7:853540-853540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1774C>T; p.Q592*; 7:869391-869391	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1564C>T; p.L522L; 7:861413-861413	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.937C>T; p.R313W; 7:853541-853541	stomach	adenocarcinoma	Substitution - Missense
c.1631G>T; p.S544I; 7:865967-865967	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.878G>A; p.C293Y; 7:853482-853482	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2049G>A; p.W683*; 7:873271-873271	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.255G>A; p.L85L; 7:842084-842084	skin	malignant_melanoma	Substitution - coding silent
c.1507G>T; p.G503W; 7:860359-860359	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.273T>C; p.R91R; 7:842102-842102	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1334G>A; p.G445D; 7:860186-860186	thyroid	other; neoplasm	Substitution - Missense
c.477G>A; p.S159S; 7:843489-843489	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.477G>A; p.S159S; 7:843489-843489	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.198C>A; p.V66V; 7:842027-842027	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1128C>A; p.T376T; 7:856384-856384	skin	malignant_melanoma	Substitution - coding silent
c.505A>T; p.K169*; 7:843517-843517	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1743C>T; p.Y581Y; 7:869360-869360	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.461delC; p.V158fs*33; 7:843473-843473	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1697G>A; p.W566*; 7:866033-866033	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1697G>A; p.W566*; 7:866033-866033	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.87C>T; p.S29S; 7:838957-838957	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.431G>T; p.R144L; 7:843443-843443	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1653C>T; p.Y551Y; 7:865989-865989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.88G>T; p.A30S; 7:838958-838958	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.673T>G; p.L225V; 7:852821-852821	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1702T>C; p.F568L; 7:866038-866038	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1498A>G; p.S500G; 7:860350-860350	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1103C>T; p.A368V; 7:856359-856359	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1103C>T; p.A368V; 7:856359-856359	skin	malignant_melanoma	Substitution - Missense
c.1400T>G; p.M467R; 7:860252-860252	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1263C>A; p.A421A; 7:857945-857945	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.642C>T; p.I214I; 7:852648-852648	skin	malignant_melanoma	Substitution - coding silent
c.1527G>T; p.E509D; 7:860379-860379	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.900C>T; p.L300L; 7:853504-853504	skin	malignant_melanoma	Substitution - coding silent
c.393C>T; p.N131N; 7:843405-843405	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.823C>A; p.P275T; 7:853427-853427	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.904G>A; p.E302K; 7:853508-853508	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.393C>T; p.N131N; 7:843405-843405	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.393C>T; p.N131N; 7:843405-843405	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1773C>T; p.S591S; 7:869390-869390	skin	malignant_melanoma	Substitution - coding silent
c.502C>T; p.Q168*; 7:843514-843514	skin	malignant_melanoma	Substitution - Nonsense
c.667C>A; p.L223I; 7:852815-852815	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.667C>A; p.L223I; 7:852815-852815	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.485A>G; p.Y162C; 7:843497-843497	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1064T>C; p.L355S; 7:854969-854969	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.693C>T; p.F231F; 7:852841-852841	skin	malignant_melanoma	Substitution - coding silent
c.1683T>C; p.F561F; 7:866019-866019	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1525G>A; p.E509K; 7:860377-860377	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.971C>T; p.P324L; 7:853575-853575	skin	malignant_melanoma	Substitution - Missense
c.583A>T; p.N195Y; 7:852024-852024	liver	carcinoma	Substitution - Missense
c.1149G>A; p.A383A; 7:857831-857831	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.583A>T; p.N195Y; 7:852024-852024	liver	carcinoma	Substitution - Missense
c.990C>T; p.D330D; 7:853594-853594	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.341C>T; p.A114V; 7:843353-843353	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1177G>A; p.E393K; 7:857859-857859	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1430G>A; p.R477Q; 7:860282-860282	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1177G>A; p.E393K; 7:857859-857859	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1177G>A; p.E393K; 7:857859-857859	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1262C>T; p.A421V; 7:857944-857944	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1177G>A; p.E393K; 7:857859-857859	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1430G>A; p.R477Q; 7:860282-860282	skin	malignant_melanoma	Substitution - Missense
c.1794G>A; p.R598R; 7:869411-869411	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.671C>T; p.S224F; 7:852819-852819	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1615+1G>A; p.?; 7:861465-861465	lung	carcinoma; adenocarcinoma	Unknown
c.257A>G; p.D86G; 7:842086-842086	liver	carcinoma	Substitution - Missense
c.773C>T; p.P258L; 7:852921-852921	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>T; p.A126A; 7:843390-843390	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.709G>A; p.V237M; 7:852857-852857	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1458C>T; p.T486T; 7:860310-860310	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1332C>T; p.G444G; 7:860184-860184	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1249G>A; p.E417K; 7:857931-857931	urinary_tract; bladder	carcinoma	Substitution - Missense
c.672C>T; p.S224S; 7:852820-852820	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1744C>T; p.P582S; 7:869361-869361	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.123delA; p.K42fs*37; 7:841952-841952	liver	carcinoma	Deletion - Frameshift
c.8G>A; p.R3H; 7:838878-838878	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.8G>A; p.R3H; 7:838878-838878	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.340G>A; p.A114T; 7:843352-843352	skin	malignant_melanoma	Substitution - Missense
c.458C>T; p.A153V; 7:843470-843470	skin	malignant_melanoma	Substitution - Missense
c.2033G>A; p.R678Q; 7:873255-873255	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.297C>T; p.F99F; 7:842126-842126	skin	malignant_melanoma	Substitution - coding silent
c.2033G>A; p.R678Q; 7:873255-873255	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1718G>A; p.R573H; 7:866054-866054	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1051C>T; p.R351C; 7:854956-854956	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]