Entrez Gene

Basic Information
Gene ID	23043
Name	TNIK
Synonymous	TRAF2 and NCK interacting kinase;TNIK;TRAF2 and NCK interacting kinase
Definition	TRAF2 and NCK-interacting protein kinase
Position	3q26.31
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2348A>T; p.E783V; 3:171108099-171108099	oesophagus	carcinoma	Substitution - Missense
c.4006T>G; p.F1336V; 3:171063958-171063958	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3894C>T; p.G1298G; 3:171066292-171066292	breast	carcinoma	Substitution - coding silent
c.3190A>G; p.T1064A; 3:171082374-171082374	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.3894C>T; p.G1298G; 3:171066292-171066292	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.34G>T; p.E12*; 3:171460030-171460030	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.34G>T; p.E12*; 3:171460030-171460030	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1137G>A; p.E379E; 3:171157544-171157544	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.308T>C; p.L103S; 3:171194634-171194634	ovary	other; neoplasm	Substitution - Missense
c.135C>G; p.V45V; 3:171228210-171228210	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1524G>A; p.Q508Q; 3:171138275-171138275	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1738C>T; p.R580*; 3:171128749-171128749	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1290G>A; p.Q430Q; 3:171140441-171140441	skin	malignant_melanoma	Substitution - coding silent
c.694C>T; p.P232S; 3:171177326-171177326	skin	malignant_melanoma	Substitution - Missense
c.586G>A; p.A196T; 3:171188755-171188755	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2449G>A; p.E817K; 3:171101591-171101591	skin	malignant_melanoma	Substitution - Missense
c.170A>T; p.D57V; 3:171228175-171228175	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1300G>A; p.E434K; 3:171140431-171140431	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3013G>A; p.E1005K; 3:171084311-171084311	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.4G>A; p.A2T; 3:171460060-171460060	liver	carcinoma	Substitution - Missense
c.1649C>T; p.A550V; 3:171128838-171128838	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3013G>A; p.E1005K; 3:171084311-171084311	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4G>A; p.A2T; 3:171460060-171460060	liver	carcinoma	Substitution - Missense
c.3013G>A; p.E1005K; 3:171084311-171084311	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2789C>T; p.P930L; 3:171087439-171087439	skin	malignant_melanoma	Substitution - Missense
c.315G>A; p.M105I; 3:171194627-171194627	skin	malignant_melanoma	Substitution - Missense
c.981G>A; p.E327E; 3:171161305-171161305	skin	malignant_melanoma	Substitution - coding silent
c.3133C>T; p.R1045*; 3:171084191-171084191	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1925C>T; p.P642L; 3:171126000-171126000	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3282A>T; p.L1094L; 3:171082282-171082282	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3282A>T; p.L1094L; 3:171082282-171082282	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2444G>A; p.R815Q; 3:171101596-171101596	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3414T>G; p.V1138V; 3:171079552-171079552	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2721+1G>A; p.?; 3:171093838-171093838	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1571G>T; p.G524V; 3:171138228-171138228	liver	carcinoma	Substitution - Missense
c.4019G>A; p.R1340Q; 3:171063945-171063945	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2419T>A; p.L807I; 3:171101621-171101621	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1705G>A; p.E569K; 3:171128782-171128782	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1705G>A; p.E569K; 3:171128782-171128782	skin	malignant_melanoma	Substitution - Missense
c.2284+2T>C; p.?; 3:171110712-171110712	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2069G>A; p.G690E; 3:171123647-171123647	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1401T>C; p.H467H; 3:171139488-171139488	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3001C>T; p.L1001L; 3:171084323-171084323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.455G>A; p.R152Q; 3:171190750-171190750	skin	malignant_melanoma	Substitution - Missense
c.4014C>T; p.S1338S; 3:171063950-171063950	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1371G>T; p.Q457H; 3:171139518-171139518	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1455delA; p.A486fs*8; 3:171138344-171138344	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.2063C>A; p.S688Y; 3:171123653-171123653	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1455delA; p.A486fs*8; 3:171138344-171138344	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.2465C>G; p.P822R; 3:171101575-171101575	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2428G>T; p.E810*; 3:171101612-171101612	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1455delA; p.A486fs*8; 3:171138344-171138344	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1455delA; p.A486fs*8; 3:171138344-171138344	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1285G>A; p.E429K; 3:171140446-171140446	skin	malignant_melanoma	Substitution - Missense
c.3914G>A; p.R1305Q; 3:171066272-171066272	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4018C>T; p.R1340*; 3:171063946-171063946	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.646T>C; p.L216L; 3:171177374-171177374	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - coding silent
c.1429C>T; p.R477C; 3:171138370-171138370	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2428G>C; p.E810Q; 3:171101612-171101612	breast	carcinoma	Substitution - Missense
c.3880A>T; p.I1294L; 3:171066306-171066306	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.177A>T; p.T59T; 3:171228168-171228168	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1155G>A; p.R385R; 3:171157526-171157526	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2509G>A; p.E837K; 3:171101531-171101531	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2145G>A; p.E715E; 3:171110853-171110853	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1201C>G; p.Q401E; 3:171157480-171157480	breast	carcinoma	Substitution - Missense
c.3393G>T; p.K1131N; 3:171079573-171079573	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2145G>A; p.E715E; 3:171110853-171110853	skin	malignant_melanoma	Substitution - coding silent
c.262G>T; p.A88S; 3:171211160-171211160	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2284+1G>A; p.?; 3:171110713-171110713	skin	malignant_melanoma	Unknown
c.2281C>T; p.R761*; 3:171110717-171110717	breast	carcinoma	Substitution - Nonsense
c.1313G>T; p.R438M; 3:171140418-171140418	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2281C>T; p.R761*; 3:171110717-171110717	skin	malignant_melanoma	Substitution - Nonsense
c.2281C>T; p.R761*; 3:171110717-171110717	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2281C>T; p.R761*; 3:171110717-171110717	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3287G>A; p.G1096E; 3:171082277-171082277	skin	malignant_melanoma	Substitution - Missense
c.416G>T; p.R139L; 3:171194526-171194526	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.724C>G; p.L242V; 3:171175301-171175301	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2544C>T; p.S848S; 3:171101496-171101496	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3200G>A; p.G1067D; 3:171082364-171082364	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2769T>C; p.F923F; 3:171087459-171087459	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2978A>T; p.D993V; 3:171085138-171085138	thyroid	carcinoma	Substitution - Missense
c.2544C>T; p.S848S; 3:171101496-171101496	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.787C>T; p.Q263*; 3:171167257-171167257	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2487C>A; p.Y829*; 3:171101553-171101553	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2544C>T; p.S848S; 3:171101496-171101496	liver	carcinoma	Substitution - coding silent
c.2544C>T; p.S848S; 3:171101496-171101496	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3023G>A; p.R1008K; 3:171084301-171084301	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4028G>A; p.G1343E; 3:171063936-171063936	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2550C>A; p.T850T; 3:171101490-171101490	breast	carcinoma	Substitution - coding silent
c.1419+1G>A; p.?; 3:171139469-171139469	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2848G>A; p.V950I; 3:171087380-171087380	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2848G>A; p.V950I; 3:171087380-171087380	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2846G>A; p.R949H; 3:171087382-171087382	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.913C>A; p.H305N; 3:171167131-171167131	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1644C>A; p.S548S; 3:171128843-171128843	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2945A>G; p.Y982C; 3:171085171-171085171	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1275G>T; p.R425R; 3:171140456-171140456	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2365C>T; p.R789W; 3:171108082-171108082	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2365C>T; p.R789W; 3:171108082-171108082	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1490G>A; p.R497K; 3:171138309-171138309	skin	malignant_melanoma	Substitution - Missense
c.341C>T; p.T114I; 3:171194601-171194601	skin	malignant_melanoma	Substitution - Missense
c.2822G>A; p.G941E; 3:171087406-171087406	skin	malignant_melanoma	Substitution - Missense
c.901C>T; p.Q301*; 3:171167143-171167143	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2706C>G; p.T902T; 3:171093854-171093854	liver	carcinoma	Substitution - coding silent
c.3808C>T; p.R1270W; 3:171066627-171066627	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.692C>T; p.P231L; 3:171177328-171177328	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1000G>A; p.D334N; 3:171161286-171161286	skin	malignant_melanoma	Substitution - Missense
c.3809G>A; p.R1270Q; 3:171066626-171066626	prostate	carcinoma	Substitution - Missense
c.1519C>T; p.R507W; 3:171138280-171138280	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3482C>T; p.A1161V; 3:171071290-171071290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.260G>A; p.G87D; 3:171211162-171211162	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.58-2A>T; p.?; 3:171369687-171369687	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.693C>T; p.P231P; 3:171177327-171177327	skin	malignant_melanoma	Substitution - coding silent
c.1257G>T; p.Q419H; 3:171140474-171140474	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2915_2916CC>TT; p.S972F; 3:171085200-171085201	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.64G>A; p.A22T; 3:171369679-171369679	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3057G>T; p.K1019N; 3:171084267-171084267	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.406G>A; p.E136K; 3:171194536-171194536	skin	malignant_melanoma	Substitution - Missense
c.3074T>A; p.V1025E; 3:171084250-171084250	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2282G>A; p.R761Q; 3:171110716-171110716	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.569G>A; p.G190E; 3:171188772-171188772	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.569G>A; p.G190E; 3:171188772-171188772	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2736G>A; p.K912K; 3:171087492-171087492	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1500A>T; p.L500F; 3:171138299-171138299	liver	carcinoma	Substitution - Missense
c.2437G>T; p.E813*; 3:171101603-171101603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1500A>T; p.L500F; 3:171138299-171138299	liver	carcinoma	Substitution - Missense
c.2574C>T; p.S858S; 3:171101466-171101466	kidney	other; neoplasm	Substitution - coding silent
c.2282G>A; p.R761Q; 3:171110716-171110716	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.569G>A; p.G190E; 3:171188772-171188772	skin	malignant_melanoma	Substitution - Missense
c.274A>G; p.K92E; 3:171211148-171211148	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3834A>G; p.Q1278Q; 3:171066601-171066601	breast	carcinoma	Substitution - coding silent
c.2105A>C; p.Q702P; 3:171123611-171123611	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2652G>A; p.G884G; 3:171093908-171093908	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3188G>A; p.G1063E; 3:171082376-171082376	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2792A>G; p.D931G; 3:171087436-171087436	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3593C>T; p.T1198M; 3:171068954-171068954	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2954C>T; p.S985F; 3:171085162-171085162	prostate	carcinoma	Substitution - Missense
c.3270G>C; p.Q1090H; 3:171082294-171082294	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.949+8G>A; p.?; 3:171167087-171167087	prostate	carcinoma	Unknown
c.885G>A; p.E295E; 3:171167159-171167159	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2318C>T; p.P773L; 3:171108129-171108129	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3551C>A; p.S1184Y; 3:171068996-171068996	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3787delG; p.V1263fs*3; 3:171066648-171066648	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1400A>G; p.H467R; 3:171139489-171139489	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2952G>A; p.T984T; 3:171085164-171085164	breast	carcinoma	Substitution - coding silent
c.274A>C; p.K92Q; 3:171211148-171211148	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1370A>G; p.Q457R; 3:171139519-171139519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1714A>C; p.S572R; 3:171128773-171128773	breast	carcinoma	Substitution - Missense
c.1345C>T; p.R449*; 3:171139544-171139544	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3792T>C; p.Y1264Y; 3:171066643-171066643	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.988G>C; p.E330Q; 3:171161298-171161298	breast	carcinoma	Substitution - Missense
c.3614T>G; p.L1205*; 3:171068933-171068933	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3103G>A; p.D1035N; 3:171084221-171084221	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1696C>T; p.P566S; 3:171128791-171128791	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.3852G>A; p.T1284T; 3:171066583-171066583	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.454C>T; p.R152*; 3:171190751-171190751	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1575G>C; p.M525I; 3:171138224-171138224	small_intestine	carcinoid-endocrine_tumour	Substitution - Missense
c.3703C>A; p.Q1235K; 3:171066732-171066732	pancreas	carcinoma	Substitution - Missense
c.1777C>T; p.P593S; 3:171126148-171126148	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2563G>A; p.V855M; 3:171101477-171101477	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1895G>A; p.R632H; 3:171126030-171126030	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2621A>G; p.Q874R; 3:171093939-171093939	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.415C>T; p.R139W; 3:171194527-171194527	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1763T>C; p.V588A; 3:171128724-171128724	breast	carcinoma	Substitution - Missense
c.2862C>T; p.S954S; 3:171087366-171087366	skin	malignant_melanoma	Substitution - coding silent
c.2784C>T; p.N928N; 3:171087444-171087444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1776C>G; p.I592M; 3:171126149-171126149	liver	carcinoma	Substitution - Missense
c.2337G>A; p.V779V; 3:171108110-171108110	skin	malignant_melanoma	Substitution - coding silent
c.1776C>G; p.I592M; 3:171126149-171126149	liver	carcinoma	Substitution - Missense
c.1909C>T; p.R637C; 3:171126016-171126016	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1909C>T; p.R637C; 3:171126016-171126016	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.3699+1G>A; p.?; 3:171068847-171068847	skin	malignant_melanoma	Unknown
c.1679C>G; p.S560C; 3:171128808-171128808	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1861G>A; p.G621R; 3:171126064-171126064	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4071G>T; p.M1357I; 3:171063893-171063893	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2995G>A; p.A999T; 3:171085121-171085121	skin	malignant_melanoma	Substitution - Missense
c.2995G>A; p.A999T; 3:171085121-171085121	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.112C>A; p.Q38K; 3:171369631-171369631	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2817A>G; p.P939P; 3:171087411-171087411	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3086A>T; p.N1029I; 3:171084238-171084238	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1357G>A; p.E453K; 3:171139532-171139532	ovary	other; neoplasm	Substitution - Missense
c.181-2A>T; p.?; 3:171211243-171211243	lung	carcinoma; adenocarcinoma	Unknown
c.2070G>A; p.G690G; 3:171123646-171123646	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.128G>C; p.R43P; 3:171228217-171228217	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4013C>T; p.S1338F; 3:171063951-171063951	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2070G>A; p.G690G; 3:171123646-171123646	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1411C>A; p.L471I; 3:171139478-171139478	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2517C>T; p.S839S; 3:171101523-171101523	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.784T>A; p.F262I; 3:171167260-171167260	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3091C>T; p.R1031W; 3:171084233-171084233	pancreas	carcinoma	Substitution - Missense
c.468G>A; p.G156G; 3:171190737-171190737	skin	malignant_melanoma	Substitution - coding silent
c.3091C>T; p.R1031W; 3:171084233-171084233	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.3091C>T; p.R1031W; 3:171084233-171084233	pancreas	carcinoma	Substitution - Missense
c.3091C>T; p.R1031W; 3:171084233-171084233	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1353A>G; p.L451L; 3:171139536-171139536	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2466A>G; p.P822P; 3:171101574-171101574	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3917C>T; p.S1306L; 3:171066269-171066269	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2226C>T; p.S742S; 3:171110772-171110772	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.495A>T; p.A165A; 3:171190710-171190710	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1992G>A; p.Q664Q; 3:171125933-171125933	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1580C>T; p.P527L; 3:171138219-171138219	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2605C>A; p.P869T; 3:171093955-171093955	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.895C>T; p.R299C; 3:171167149-171167149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2956C>T; p.P986S; 3:171085160-171085160	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1931C>T; p.S644L; 3:171125994-171125994	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2545G>T; p.E849*; 3:171101495-171101495	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2828C>T; p.P943L; 3:171087400-171087400	skin	malignant_melanoma	Substitution - Missense
c.3228A>G; p.Q1076Q; 3:171082336-171082336	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.9C>T; p.S3S; 3:171460055-171460055	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1430G>A; p.R477H; 3:171138369-171138369	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2529G>A; p.E843E; 3:171101511-171101511	breast	carcinoma	Substitution - coding silent
c.886C>T; p.R296*; 3:171167158-171167158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2630T>A; p.V877E; 3:171093930-171093930	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.891G>T; p.Q297H; 3:171167153-171167153	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2607A>G; p.P869P; 3:171093953-171093953	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2971G>A; p.E991K; 3:171085145-171085145	skin	malignant_melanoma	Substitution - Missense
c.2845C>T; p.R949C; 3:171087383-171087383	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1323G>A; p.E441E; 3:171140408-171140408	skin	malignant_melanoma	Substitution - coding silent
c.2651G>T; p.G884V; 3:171093909-171093909	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3716C>T; p.T1239I; 3:171066719-171066719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1154G>A; p.R385Q; 3:171157527-171157527	pancreas	carcinoma	Substitution - Missense
c.1545G>T; p.K515N; 3:171138254-171138254	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3086A>G; p.N1029S; 3:171084238-171084238	breast	carcinoma	Substitution - Missense
c.1310G>A; p.R437K; 3:171140421-171140421	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3217C>T; p.R1073*; 3:171082347-171082347	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.136A>G; p.K46E; 3:171228209-171228209	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.136A>G; p.K46E; 3:171228209-171228209	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3674C>T; p.S1225F; 3:171068873-171068873	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2645C>T; p.T882M; 3:171093915-171093915	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1385A>T; p.Q462L; 3:171139504-171139504	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1731G>C; p.Q577H; 3:171128756-171128756	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.2645C>T; p.T882M; 3:171093915-171093915	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.3392A>G; p.K1131R; 3:171079574-171079574	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3568C>T; p.H1190Y; 3:171068979-171068979	pancreas	carcinoma	Substitution - Missense
c.3976T>A; p.F1326I; 3:171066210-171066210	skin	malignant_melanoma	Substitution - Missense
c.539G>A; p.R180Q; 3:171188802-171188802	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2682C>T; p.S894S; 3:171093878-171093878	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3480T>C; p.I1160I; 3:171071292-171071292	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3062C>T; p.S1021L; 3:171084262-171084262	skin	malignant_melanoma	Substitution - Missense
c.2520G>T; p.E840D; 3:171101520-171101520	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3443A>C; p.K1148T; 3:171079523-171079523	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2428G>A; p.E810K; 3:171101612-171101612	skin	malignant_melanoma	Substitution - Missense
c.2520G>T; p.E840D; 3:171101520-171101520	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1333G>T; p.E445*; 3:171139556-171139556	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.3062C>T; p.S1021L; 3:171084262-171084262	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.510G>A; p.V170V; 3:171188831-171188831	skin	malignant_melanoma	Substitution - coding silent
c.2172G>A; p.R724R; 3:171110826-171110826	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.371C>A; p.T124K; 3:171194571-171194571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3801C>A; p.T1267T; 3:171066634-171066634	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1842G>T; p.Q614H; 3:171126083-171126083	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1723G>A; p.G575R; 3:171128764-171128764	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3494C>T; p.A1165V; 3:171071278-171071278	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.697C>T; p.L233F; 3:171175328-171175328	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.749C>T; p.A250V; 3:171175276-171175276	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1135G>A; p.E379K; 3:171157546-171157546	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4008delT; p.F1336fs*15; 3:171063956-171063956	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.602C>T; p.A201V; 3:171188739-171188739	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.783delA; p.K261fs*11; 3:171167261-171167261	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.783delA; p.K261fs*11; 3:171167261-171167261	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.883G>A; p.E295K; 3:171167161-171167161	skin	malignant_melanoma	Substitution - Missense
c.2262C>T; p.S754S; 3:171110736-171110736	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3241_3251del11; p.N1081fs*25; 3:171082313-171082323	skin; back	malignant_melanoma	Deletion - Frameshift
c.1210C>T; p.R404W; 3:171157471-171157471	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.835G>T; p.A279S; 3:171167209-171167209	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.275_276insA; p.N93fs*7; 3:171211146-171211147	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3136T>C; p.F1046L; 3:171084188-171084188	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.3794T>C; p.V1265A; 3:171066641-171066641	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.466G>T; p.G156W; 3:171190739-171190739	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3136T>C; p.F1046L; 3:171084188-171084188	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.155C>T; p.A52V; 3:171228190-171228190	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3017T>C; p.L1006P; 3:171084307-171084307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2836G>A; p.G946R; 3:171087392-171087392	skin	malignant_melanoma	Substitution - Missense
c.3296T>A; p.V1099D; 3:171082268-171082268	skin	malignant_melanoma	Substitution - Missense
c.1315C>T; p.R439C; 3:171140416-171140416	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.2347G>T; p.E783*; 3:171108100-171108100	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3529C>T; p.H1177Y; 3:171071243-171071243	skin	malignant_melanoma	Substitution - Missense
c.1611A>G; p.V537V; 3:171128876-171128876	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1785G>A; p.L595L; 3:171126140-171126140	breast	carcinoma	Substitution - coding silent
c.1242G>T; p.E414D; 3:171140489-171140489	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2330C>T; p.A777V; 3:171108117-171108117	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.485C>A; p.T162N; 3:171190720-171190720	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3275A>C; p.D1092A; 3:171082289-171082289	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1216G>A; p.E406K; 3:171157465-171157465	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2316C>T; p.L772L; 3:171108131-171108131	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3374A>G; p.N1125S; 3:171079592-171079592	skin	malignant_melanoma	Substitution - Missense
c.3640G>T; p.G1214C; 3:171068907-171068907	skin	malignant_melanoma	Substitution - Missense
c.2316C>T; p.L772L; 3:171108131-171108131	breast	carcinoma	Substitution - coding silent
c.382G>C; p.E128Q; 3:171194560-171194560	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.824G>T; p.S275I; 3:171167220-171167220	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2787C>T; p.L929L; 3:171087441-171087441	skin	malignant_melanoma	Substitution - coding silent
c.1683C>A; p.D561E; 3:171128804-171128804	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.824G>T; p.S275I; 3:171167220-171167220	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.198C>G; p.I66M; 3:171211224-171211224	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1683C>A; p.D561E; 3:171128804-171128804	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1902G>A; p.E634E; 3:171126023-171126023	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2585G>A; p.R862K; 3:171101455-171101455	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3974A>C; p.K1325T; 3:171066212-171066212	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.741G>A; p.R247R; 3:171175284-171175284	skin	malignant_melanoma	Substitution - coding silent
c.3403T>C; p.W1135R; 3:171079563-171079563	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2340A>G; p.K780K; 3:171108107-171108107	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.338T>C; p.V113A; 3:171194604-171194604	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.354G>T; p.K118N; 3:171194588-171194588	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3314G>A; p.G1105E; 3:171079652-171079652	skin	malignant_melanoma	Substitution - Missense
c.3061T>A; p.S1021T; 3:171084263-171084263	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.706A>G; p.M236V; 3:171175319-171175319	pancreas	carcinoma	Substitution - Missense
c.706A>G; p.M236V; 3:171175319-171175319	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1380C>A; p.I460I; 3:171139509-171139509	liver	carcinoma	Substitution - coding silent
c.2104C>T; p.Q702*; 3:171123612-171123612	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2133C>T; p.L711L; 3:171110865-171110865	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2724G>A; p.T908T; 3:171087504-171087504	prostate	carcinoma	Substitution - coding silent
c.2663C>A; p.S888Y; 3:171093897-171093897	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3221G>C; p.S1074T; 3:171082343-171082343	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1774-1G>T; p.?; 3:171126152-171126152	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.943G>T; p.E315*; 3:171167101-171167101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.943G>T; p.E315*; 3:171167101-171167101	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.132T>C; p.H44H; 3:171228213-171228213	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.206A>T; p.E69V; 3:171211216-171211216	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3082A>G; p.T1028A; 3:171084242-171084242	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3859G>A; p.A1287T; 3:171066576-171066576	skin	malignant_melanoma	Substitution - Missense
c.424A>G; p.S142G; 3:171190781-171190781	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1703C>T; p.S568L; 3:171128784-171128784	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.666C>T; p.T222T; 3:171177354-171177354	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3964C>G; p.Q1322E; 3:171066222-171066222	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3377A>C; p.D1126A; 3:171079589-171079589	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3029A>G; p.E1010G; 3:171084295-171084295	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3732C>T; p.V1244V; 3:171066703-171066703	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2994C>T; p.A998A; 3:171085122-171085122	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]