Entrez Gene

Basic Information
Gene ID	2077
Name	ERF
Synonymous	Ets2 repressor factor;ERF;Ets2 repressor factor
Definition	ETS domain-containing transcription factor ERF
Position	19q13
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.165C>T; p.F55F; 19:42250423-42250423	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.444G>A; p.T148T; 19:42249668-42249668	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.589G>T; p.E197*; 19:42249523-42249523	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.251C>T; p.A84V; 19:42250337-42250337	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1459C>T; p.R487C; 19:42248653-42248653	skin	malignant_melanoma	Substitution - Missense
c.926A>G; p.D309G; 19:42249186-42249186	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.607G>A; p.D203N; 19:42249505-42249505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.133G>A; p.V45I; 19:42250455-42250455	skin	malignant_melanoma	Substitution - Missense
c.416G>T; p.G139V; 19:42249696-42249696	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.416G>T; p.G139V; 19:42249696-42249696	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.909C>A; p.F303L; 19:42249203-42249203	liver	carcinoma	Substitution - Missense
c.909C>A; p.F303L; 19:42249203-42249203	liver	carcinoma	Substitution - Missense
c.1498C>T; p.P500S; 19:42248614-42248614	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1456C>T; p.R486W; 19:42248656-42248656	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1456C>T; p.R486W; 19:42248656-42248656	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.615C>G; p.R205R; 19:42249497-42249497	thyroid	other; neoplasm	Substitution - coding silent
c.615C>G; p.R205R; 19:42249497-42249497	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.179C>T; p.P60L; 19:42250409-42250409	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1156C>T; p.R386C; 19:42248956-42248956	skin	malignant_melanoma	Substitution - Missense
c.615C>G; p.R205R; 19:42249497-42249497	thyroid	other; neoplasm	Substitution - coding silent
c.489A>G; p.P163P; 19:42249623-42249623	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1590G>T; p.V530V; 19:42248522-42248522	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1362C>G; p.F454L; 19:42248750-42248750	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.911C>T; p.S304F; 19:42249201-42249201	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.579G>A; p.T193T; 19:42249533-42249533	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1377C>G; p.A459A; 19:42248735-42248735	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.205G>A; p.V69I; 19:42250383-42250383	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1490G>A; p.G497D; 19:42248622-42248622	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.940C>A; p.L314M; 19:42249172-42249172	liver	carcinoma	Substitution - Missense
c.1293G>A; p.S431S; 19:42248819-42248819	skin	malignant_melanoma	Substitution - coding silent
c.1305G>A; p.S435S; 19:42248807-42248807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1482C>T; p.L494L; 19:42248630-42248630	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1230T>C; p.A410A; 19:42248882-42248882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1230T>C; p.A410A; 19:42248882-42248882	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1230T>C; p.A410A; 19:42248882-42248882	thyroid	other; neoplasm	Substitution - coding silent
c.275G>A; p.R92H; 19:42249925-42249925	thyroid	carcinoma	Substitution - Missense
c.275G>A; p.R92H; 19:42249925-42249925	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.503C>T; p.S168F; 19:42249609-42249609	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.985C>T; p.R329C; 19:42249127-42249127	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.745C>A; p.P249T; 19:42249367-42249367	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.794C>T; p.S265F; 19:42249318-42249318	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.506C>T; p.S169L; 19:42249606-42249606	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.616G>A; p.A206T; 19:42249496-42249496	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1565G>T; p.G522V; 19:42248547-42248547	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.896delG; p.G299fs*12; 19:42249216-42249216	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.896delG; p.G299fs*12; 19:42249216-42249216	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.157G>A; p.G53R; 19:42250431-42250431	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.415G>A; p.G139S; 19:42249697-42249697	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.204C>T; p.G68G; 19:42250384-42250384	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1523G>T; p.G508V; 19:42248589-42248589	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1259C>T; p.P420L; 19:42248853-42248853	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1624T>G; p.S542A; 19:42248488-42248488	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.65C>G; p.P22R; 19:42250523-42250523	urinary_tract; bladder	carcinoma	Substitution - Missense
c.175G>A; p.D59N; 19:42250413-42250413	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.839C>T; p.S280L; 19:42249273-42249273	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.839C>T; p.S280L; 19:42249273-42249273	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.502T>C; p.S168P; 19:42249610-42249610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1166G>T; p.R389L; 19:42248946-42248946	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1086C>A; p.S362S; 19:42249026-42249026	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.797delC; p.P266fs*5; 19:42249315-42249315	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1052C>T; p.P351L; 19:42249060-42249060	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1496delG; p.G499fs*32; 19:42248616-42248616	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1148_1149insC; p.L384fs*17; 19:42248963-42248964	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Insertion - Frameshift
c.978C>T; p.L326L; 19:42249134-42249134	breast	carcinoma	Substitution - coding silent
c.121G>A; p.E41K; 19:42250467-42250467	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1085C>T; p.S362F; 19:42249027-42249027	skin	malignant_melanoma	Substitution - Missense
c.1350C>A; p.D450E; 19:42248762-42248762	liver	carcinoma	Substitution - Missense
c.525T>C; p.A175A; 19:42249587-42249587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.973C>A; p.H325N; 19:42249139-42249139	skin	malignant_melanoma	Substitution - Missense
c.659C>A; p.P220H; 19:42249453-42249453	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.912C>T; p.S304S; 19:42249200-42249200	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1491T>C; p.G497G; 19:42248621-42248621	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.463C>A; p.P155T; 19:42249649-42249649	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1083_1084insC; p.S362fs*17; 19:42249028-42249029	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Insertion - Frameshift
c.1573C>T; p.L525F; 19:42248539-42248539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.840G>A; p.S280S; 19:42249272-42249272	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.492C>T; p.A164A; 19:42249620-42249620	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1362C>A; p.F454L; 19:42248750-42248750	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.575G>A; p.G192D; 19:42249537-42249537	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1617C>T; p.A539A; 19:42248495-42248495	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.789delG; p.Q263fs*8; 19:42249323-42249323	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1541G>A; p.R514H; 19:42248571-42248571	breast	carcinoma	Substitution - Missense
c.96T>G; p.F32L; 19:42250492-42250492	skin	malignant_melanoma	Substitution - Missense
c.1575C>G; p.L525L; 19:42248537-42248537	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.854C>T; p.P285L; 19:42249258-42249258	skin	malignant_melanoma	Substitution - Missense
c.1046C>A; p.P349Q; 19:42249066-42249066	stomach	adenocarcinoma	Substitution - Missense
c.1103C>T; p.S368F; 19:42249009-42249009	skin	malignant_melanoma	Substitution - Missense
c.1614G>A; p.T538T; 19:42248498-42248498	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1553C>T; p.P518L; 19:42248559-42248559	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100C>T; p.S367F; 19:42249012-42249012	skin	malignant_melanoma	Substitution - Missense
c.408G>A; p.P136P; 19:42249704-42249704	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.478C>T; p.R160C; 19:42249634-42249634	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1275C>T; p.I425I; 19:42248837-42248837	skin	malignant_melanoma	Substitution - coding silent
c.1237G>A; p.A413T; 19:42248875-42248875	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1237G>A; p.A413T; 19:42248875-42248875	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1478G>A; p.R493H; 19:42248634-42248634	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1237G>A; p.A413T; 19:42248875-42248875	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1300G>A; p.E434K; 19:42248812-42248812	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1222G>A; p.G408R; 19:42248890-42248890	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.199T>G; p.W67G; 19:42250389-42250389	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.209G>A; p.R70H; 19:42250379-42250379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.199T>G; p.W67G; 19:42250389-42250389	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.619C>T; p.R207*; 19:42249493-42249493	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.23-1G>T; p.?; 19:42250566-42250566	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Unknown
c.370G>A; p.A124T; 19:42249830-42249830	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1430G>A; p.C477Y; 19:42248682-42248682	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1094C>T; p.S365L; 19:42249018-42249018	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1460G>T; p.R487L; 19:42248652-42248652	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.981C>T; p.S327S; 19:42249131-42249131	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1095G>A; p.S365S; 19:42249017-42249017	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1334A>C; p.D445A; 19:42248778-42248778	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]