Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1848

Name

DUSP6

Synonymous

dual specificity phosphatase 6;DUSP6;dual specificity phosphatase 6

Definition

MAP kinase phosphatase 3|dual specificity protein phosphatase 6|dual specificity protein phosphatase PYST1|mitogen-activated protein kinase phosphatase 3|serine/threonine specific protein phosphatase

Position

12q22-q23

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.450T>C; p.N150N; 12:89350976-89350976

 breastcarcinomaSubstitution - coding silent

c.815delT; p.F272fs*8; 12:89350611-89350611

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.899C>T; p.S300L; 12:89349501-89349501

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.899C>T; p.S300L; 12:89349501-89349501

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.901G>A; p.V301I; 12:89349499-89349499

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.800A>G; p.N267S; 12:89350626-89350626

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.800A>G; p.N267S; 12:89350626-89350626

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.582G>A; p.S194S; 12:89350844-89350844

 pancreascarcinoma; ductal_carcinomaSubstitution - coding silent

c.553G>C; p.D185H; 12:89350873-89350873

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.375G>T; p.E125D; 12:89351665-89351665

 thyroidother; neoplasmSubstitution - Missense

c.620C>A; p.P207Q; 12:89350806-89350806

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.620C>A; p.P207Q; 12:89350806-89350806

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.715G>A; p.V239I; 12:89350711-89350711

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.762A>G; p.K254K; 12:89350664-89350664

 livercarcinomaSubstitution - coding silent

c.1139C>T; p.S380F; 12:89349261-89349261

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1139C>T; p.S380F; 12:89349261-89349261

 skin; extremitymalignant_melanomaSubstitution - Missense

c.93C>A; p.N31K; 12:89351947-89351947

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.830C>A; p.S277Y; 12:89350596-89350596

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.73G>A; p.E25K; 12:89351967-89351967

 breastcarcinomaSubstitution - Missense

c.729G>A; p.L243L; 12:89350697-89350697

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.855G>T; p.K285N; 12:89349545-89349545

 prostateadenomaSubstitution - Missense

c.231C>T; p.F77F; 12:89351809-89351809

 thyroidcarcinomaSubstitution - coding silent

c.1009A>T; p.M337L; 12:89349391-89349391

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.810G>C; p.Q270H; 12:89350616-89350616

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.952G>C; p.D318H; 12:89349448-89349448

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1133_1134insT; p.Q379fs*>4; 12:89349266-89349267

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.742G>T; p.E248*; 12:89350684-89350684

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.66G>A; p.W22*; 12:89351974-89351974

 pancreascarcinomaSubstitution - Nonsense

c.340G>T; p.V114L; 12:89351700-89351700

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.340G>T; p.V114L; 12:89351700-89351700

 thyroidother; neoplasmSubstitution - Missense

c.634C>T; p.P212S; 12:89350792-89350792

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.634C>T; p.P212S; 12:89350792-89350792

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.736C>A; p.L246I; 12:89350690-89350690

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.523G>A; p.D175N; 12:89350903-89350903

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.523G>A; p.D175N; 12:89350903-89350903

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1005C>T; p.N335N; 12:89349395-89349395

 breastcarcinomaSubstitution - coding silent

c.1022T>G; p.L341R; 12:89349378-89349378

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.526T>C; p.S176P; 12:89350900-89350900

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.247C>T; p.R83W; 12:89351793-89351793

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.556C>T; p.R186*; 12:89350870-89350870

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.656C>A; p.A219D; 12:89350770-89350770

 skin; earcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.505_506delGG; p.G169fs*6; 12:89350920-89350921

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.896G>A; p.R299H; 12:89349504-89349504

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1016A>T; p.Q339L; 12:89349384-89349384

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.348G>A; p.G116G; 12:89351692-89351692

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.972A>G; p.K324K; 12:89349428-89349428

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.543G>A; p.E181E; 12:89350883-89350883

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.911C>T; p.T304I; 12:89349489-89349489

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.611C>T; p.P204L; 12:89350815-89350815

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.550C>A; p.L184I; 12:89350876-89350876

 thyroidother; neoplasmSubstitution - Missense

c.611C>T; p.P204L; 12:89350815-89350815

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.611C>T; p.P204L; 12:89350815-89350815

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.25C>T; p.P9S; 12:89352015-89352015

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1110G>C; p.Q370H; 12:89349290-89349290

 pancreascarcinomaSubstitution - Missense

c.1110G>C; p.Q370H; 12:89349290-89349290

 lungcarcinoma; adenocarcinomaSubstitution - Missense

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