Entrez Gene

Basic Information
Gene ID	142
Name	PARP1
Synonymous	poly (ADP-ribose) polymerase 1;PARP1;poly (ADP-ribose) polymerase 1
Definition	ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)\|ADP-ribosyltransferase NAD(+)\|ADP-ribosyltransferase diphtheria toxin-like 1\|NAD(+) ADP-ribosyltransferase 1\|poly (ADP-ribose) polymerase family, member 1\|poly [ADP-ribose] polymerase 1\|poly(ADP-
Position	1q41-q42
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1229C>T; p.A410V; 1:226381139-226381139	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.236G>T; p.W79L; 1:226402264-226402264	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.236G>T; p.W79L; 1:226402264-226402264	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1673G>T; p.G558V; 1:226379214-226379214	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2893G>A; p.D965N; 1:226362039-226362039	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2032G>C; p.D678H; 1:226374264-226374264	breast	carcinoma	Substitution - Missense
c.2032G>C; p.D678H; 1:226374264-226374264	parathyroid	carcinoma	Substitution - Missense
c.2125G>A; p.A709T; 1:226370463-226370463	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2125G>A; p.A709T; 1:226370463-226370463	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.608A>G; p.K203R; 1:226390419-226390419	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2717A>G; p.N906S; 1:226364012-226364012	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.519G>A; p.R173R; 1:226390508-226390508	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2695G>A; p.D899N; 1:226364034-226364034	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2794C>T; p.L932L; 1:226363153-226363153	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1383C>T; p.D461D; 1:226380082-226380082	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.1268C>T; p.A423V; 1:226381100-226381100	pancreas	carcinoma	Substitution - Missense
c.835A>C; p.I279L; 1:226385680-226385680	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2124C>T; p.A708A; 1:226370464-226370464	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2124C>T; p.A708A; 1:226370464-226370464	pancreas	carcinoma	Substitution - coding silent
c.2124C>T; p.A708A; 1:226370464-226370464	pancreas	carcinoma	Substitution - coding silent
c.2483C>T; p.A828V; 1:226365976-226365976	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1443G>C; p.W481C; 1:226380022-226380022	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1947A>C; p.E649D; 1:226374349-226374349	skin	malignant_melanoma	Substitution - Missense
c.1508T>G; p.L503R; 1:226379957-226379957	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1905C>G; p.P635P; 1:226377144-226377144	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2728A>G; p.T910A; 1:226364001-226364001	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1888A>C; p.N630H; 1:226377161-226377161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1703C>G; p.S568C; 1:226379184-226379184	breast	carcinoma	Substitution - Missense
c.1872C>T; p.N624N; 1:226377177-226377177	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.652G>A; p.E218K; 1:226388721-226388721	skin	malignant_melanoma	Substitution - Missense
c.1872C>T; p.N624N; 1:226377177-226377177	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2919C>T; p.T973T; 1:226362013-226362013	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1872C>T; p.N624N; 1:226377177-226377177	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1965G>A; p.L655L; 1:226374331-226374331	breast	carcinoma	Substitution - coding silent
c.91G>A; p.D31N; 1:226407839-226407839	thyroid	other; neoplasm	Substitution - Missense
c.2382T>A; p.Y794*; 1:226367504-226367504	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2691C>T; p.F897F; 1:226364038-226364038	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2691C>T; p.F897F; 1:226364038-226364038	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1771C>T; p.R591C; 1:226377278-226377278	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1209G>A; p.R403R; 1:226381159-226381159	breast	carcinoma	Substitution - coding silent
c.2296G>A; p.D766N; 1:226367590-226367590	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2422T>A; p.S808T; 1:226366037-226366037	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1505C>T; p.A502V; 1:226379960-226379960	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.229C>A; p.L77I; 1:226402271-226402271	breast	carcinoma	Substitution - Missense
c.1505C>T; p.A502V; 1:226379960-226379960	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1505C>T; p.A502V; 1:226379960-226379960	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1505C>T; p.A502V; 1:226379960-226379960	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.1505C>T; p.A502V; 1:226379960-226379960	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.1505C>T; p.A502V; 1:226379960-226379960	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.790C>G; p.L264V; 1:226386370-226386370	lung	carcinoma; undifferentiated_carcinoma	Substitution - Missense
c.1159+2T>C; p.?; 1:226383034-226383034	pleura	pulmonary_blastoma	Unknown
c.26A>G; p.Y9C; 1:226407904-226407904	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.2398G>A; p.D800N; 1:226367488-226367488	breast	carcinoma	Substitution - Missense
c.2626_2627GG>AA; p.G876N; 1:226365033-226365034	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.533C>T; p.A178V; 1:226390494-226390494	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.450G>A; p.Q150Q; 1:226390577-226390577	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.533C>T; p.A178V; 1:226390494-226390494	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1873G>A; p.A625T; 1:226377176-226377176	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1873G>A; p.A625T; 1:226377176-226377176	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.833C>T; p.A278V; 1:226386327-226386327	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1195G>T; p.G399W; 1:226381173-226381173	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1259C>T; p.T420M; 1:226381109-226381109	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1623C>T; p.H541H; 1:226379264-226379264	skin	malignant_melanoma	Substitution - coding silent
c.2503G>A; p.D835N; 1:226365956-226365956	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2684T>C; p.I895T; 1:226364045-226364045	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1967C>T; p.T656I; 1:226374329-226374329	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1893C>T; p.F631F; 1:226377156-226377156	skin	malignant_melanoma	Substitution - coding silent
c.713T>C; p.L238P; 1:226388660-226388660	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2831G>A; p.G944D; 1:226363116-226363116	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1883C>A; p.S628Y; 1:226377166-226377166	kidney	other; neoplasm	Substitution - Missense
c.76G>C; p.E26Q; 1:226407854-226407854	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2586C>T; p.H862H; 1:226365074-226365074	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1614A>T; p.G538G; 1:226379273-226379273	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.597C>T; p.L199L; 1:226390430-226390430	skin	malignant_melanoma	Substitution - coding silent
c.1614A>T; p.G538G; 1:226379273-226379273	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2423C>G; p.S808C; 1:226366036-226366036	central_nervous_system; brain	glioma	Substitution - Missense
c.1076_1077insC; p.E360fs*29; 1:226383118-226383119	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1541A>G; p.E514G; 1:226379924-226379924	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1845G>A; p.M615I; 1:226377204-226377204	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2249C>T; p.P750L; 1:226368227-226368227	pancreas	carcinoma	Substitution - Missense
c.1845G>A; p.M615I; 1:226377204-226377204	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1389C>T; p.S463S; 1:226380076-226380076	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2258A>G; p.N753S; 1:226368218-226368218	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1106C>T; p.P369L; 1:226383089-226383089	breast	carcinoma	Substitution - Missense
c.1771C>A; p.R591S; 1:226377278-226377278	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1023A>G; p.E341E; 1:226383172-226383172	prostate	carcinoma	Substitution - coding silent
c.834+1G>A; p.?; 1:226386325-226386325	skin; trunk	malignant_melanoma	Unknown
c.897G>T; p.S299S; 1:226385618-226385618	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - coding silent
c.844C>T; p.R282*; 1:226385671-226385671	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1772G>A; p.R591H; 1:226377277-226377277	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2088G>A; p.M696I; 1:226370500-226370500	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2872C>T; p.P958S; 1:226362060-226362060	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1783G>T; p.V595L; 1:226377266-226377266	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2214C>T; p.T738T; 1:226368262-226368262	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2563C>A; p.H855N; 1:226365097-226365097	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.438G>A; p.P146P; 1:226390589-226390589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2663G>A; p.G888D; 1:226364066-226364066	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.630C>T; p.G210G; 1:226388743-226388743	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.630C>T; p.G210G; 1:226388743-226388743	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1843A>G; p.M615V; 1:226377206-226377206	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1843A>G; p.M615V; 1:226377206-226377206	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1843A>G; p.M615V; 1:226377206-226377206	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2901A>C; p.V967V; 1:226362031-226362031	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2920G>A; p.G974R; 1:226362012-226362012	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1675C>A; p.L559M; 1:226379212-226379212	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.803A>G; p.N268S; 1:226386357-226386357	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2276A>C; p.Q759P; 1:226368200-226368200	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.940G>A; p.D314N; 1:226385575-226385575	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.243C>T; p.D81D; 1:226402257-226402257	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.312C>A; p.S104R; 1:226392289-226392289	breast	carcinoma	Substitution - Missense
c.3035C>T; p.S1012F; 1:226361470-226361470	skin	malignant_melanoma	Substitution - Missense
c.2738delG; p.G913fs*4; 1:226363991-226363991	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2738delG; p.G913fs*4; 1:226363991-226363991	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1832T>C; p.I611T; 1:226377217-226377217	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.2226C>T; p.H742H; 1:226368250-226368250	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.601G>T; p.G201*; 1:226390426-226390426	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2433C>T; p.A811A; 1:226366026-226366026	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2433C>T; p.A811A; 1:226366026-226366026	breast	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2695G>T; p.D899Y; 1:226364034-226364034	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.787G>A; p.E263K; 1:226386373-226386373	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1501G>A; p.A501T; 1:226379964-226379964	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2332C>T; p.L778F; 1:226367554-226367554	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1447delG; p.A483fs*3; 1:226380018-226380018	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.645A>C; p.G215G; 1:226388728-226388728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1604C>A; p.P535H; 1:226379581-226379581	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1265C>T; p.T422M; 1:226381103-226381103	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1975C>T; p.P659S; 1:226374321-226374321	skin	malignant_melanoma	Substitution - Missense
c.2458A>G; p.N820D; 1:226366001-226366001	central_nervous_system; brain	glioma	Substitution - Missense
c.2155-1G>T; p.?; 1:226368322-226368322	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.2203C>T; p.R735C; 1:226368273-226368273	skin	malignant_melanoma	Substitution - Missense
c.2570G>A; p.R857Q; 1:226365090-226365090	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.852T>C; p.A284A; 1:226385663-226385663	thyroid	other; neoplasm	Substitution - coding silent
c.2730G>A; p.T910T; 1:226363999-226363999	prostate	carcinoma	Substitution - coding silent
c.2808A>G; p.S936S; 1:226363139-226363139	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1843A>T; p.M615L; 1:226377206-226377206	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1844T>C; p.M615T; 1:226377205-226377205	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1055A>G; p.K352R; 1:226383140-226383140	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1844T>C; p.M615T; 1:226377205-226377205	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1788C>T; p.I596I; 1:226377261-226377261	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.918C>T; p.S306S; 1:226385597-226385597	breast	carcinoma	Substitution - coding silent
c.918C>T; p.S306S; 1:226385597-226385597	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2645C>T; p.P882L; 1:226365015-226365015	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.3023A>G; p.N1008S; 1:226361482-226361482	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.897G>A; p.S299S; 1:226385618-226385618	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.242A>G; p.D81G; 1:226402258-226402258	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2285T>C; p.V762A; 1:226367601-226367601	thyroid	other; neoplasm	Substitution - Missense
c.2285T>C; p.V762A; 1:226367601-226367601	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1251delG; p.K418fs*2; 1:226381117-226381117	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3021C>T; p.F1007F; 1:226361484-226361484	skin	malignant_melanoma	Substitution - coding silent
c.2067T>C; p.Y689Y; 1:226374229-226374229	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2814C>T; p.I938I; 1:226363133-226363133	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1463A>T; p.E488V; 1:226380002-226380002	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1092C>T; p.S364S; 1:226383103-226383103	skin	malignant_melanoma	Substitution - coding silent
c.402G>T; p.K134N; 1:226392199-226392199	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1064G>A; p.R355H; 1:226383131-226383131	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3037C>T; p.L1013L; 1:226361468-226361468	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2539C>T; p.R847C; 1:226365121-226365121	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1494G>A; p.K498K; 1:226379971-226379971	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1019G>A; p.R340Q; 1:226383176-226383176	pancreas	carcinoma	Substitution - Missense
c.2685C>T; p.I895I; 1:226364044-226364044	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2817C>T; p.S939S; 1:226363130-226363130	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2410G>T; p.V804F; 1:226366049-226366049	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1804G>C; p.E602Q; 1:226377245-226377245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1804G>C; p.E602Q; 1:226377245-226377245	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.639G>A; p.V213V; 1:226388734-226388734	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1531G>A; p.V511I; 1:226379934-226379934	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2439C>T; p.I813I; 1:226366020-226366020	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1093G>A; p.V365M; 1:226383102-226383102	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.282G>T; p.V94V; 1:226402218-226402218	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1056A>G; p.K352K; 1:226383139-226383139	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1056A>G; p.K352K; 1:226383139-226383139	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1056A>G; p.K352K; 1:226383139-226383139	thyroid	other; neoplasm	Substitution - coding silent
c.2632C>T; p.R878W; 1:226365028-226365028	pancreas	carcinoma	Substitution - Missense
c.1301-1G>C; p.?; 1:226380165-226380165	urinary_tract; bladder	carcinoma	Unknown
c.1223T>G; p.V408G; 1:226381145-226381145	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.943G>A; p.V315I; 1:226385572-226385572	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1042T>G; p.L348V; 1:226383153-226383153	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2054C>T; p.A685V; 1:226374242-226374242	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.919G>A; p.D307N; 1:226385596-226385596	breast	carcinoma	Substitution - Missense
c.501G>A; p.R167R; 1:226390526-226390526	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1678G>C; p.V560L; 1:226379209-226379209	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1678G>A; p.V560M; 1:226379209-226379209	skin	malignant_melanoma	Substitution - Missense
c.1916A>G; p.Y639C; 1:226377133-226377133	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2856C>T; p.G952G; 1:226362076-226362076	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.881C>T; p.P294L; 1:226385634-226385634	skin; upper_back	malignant_melanoma	Substitution - Missense
c.1838A>G; p.H613R; 1:226377211-226377211	skin	malignant_melanoma	Substitution - Missense
c.2589G>C; p.G863G; 1:226365071-226365071	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2431G>A; p.A811T; 1:226366028-226366028	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.882C>T; p.P294P; 1:226385633-226385633	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.659C>T; p.A220V; 1:226388714-226388714	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1110G>A; p.P370P; 1:226383085-226383085	liver	carcinoma	Substitution - coding silent
c.1555T>G; p.S519A; 1:226379630-226379630	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1110G>A; p.P370P; 1:226383085-226383085	liver	carcinoma	Substitution - coding silent
c.946A>G; p.T316A; 1:226385569-226385569	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2590T>G; p.S864A; 1:226365070-226365070	thyroid	other; neoplasm	Substitution - Missense
c.177G>T; p.K59N; 1:226402323-226402323	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1419C>A; p.F473L; 1:226380046-226380046	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.177G>T; p.K59N; 1:226402323-226402323	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2842G>A; p.V948I; 1:226363105-226363105	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1668C>T; p.T556T; 1:226379219-226379219	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1668C>T; p.T556T; 1:226379219-226379219	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.660G>A; p.A220A; 1:226388713-226388713	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2370C>T; p.I790I; 1:226367516-226367516	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1092C>A; p.S364S; 1:226383103-226383103	skin	malignant_melanoma	Substitution - coding silent
c.530G>A; p.S177N; 1:226390497-226390497	liver	carcinoma	Substitution - Missense
c.530G>A; p.S177N; 1:226390497-226390497	liver	carcinoma	Substitution - Missense
c.2642C>T; p.P881L; 1:226365018-226365018	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1895C>T; p.T632M; 1:226377154-226377154	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2683A>G; p.I895V; 1:226364046-226364046	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.663G>T; p.K221N; 1:226388710-226388710	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1895C>T; p.T632M; 1:226377154-226377154	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.1817C>T; p.S606F; 1:226377232-226377232	skin	malignant_melanoma	Substitution - Missense
c.1703C>T; p.S568F; 1:226379184-226379184	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]