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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10783

Name

NEK6

Synonymous

NIMA-related kinase 6;NEK6;NIMA-related kinase 6

Definition

NIMA (never in mitosis gene a)-related kinase 6|never in mitosis A-related kinase 6|nimA-related protein kinase 6|protein kinase SID6-1512|putative serine-threonine protein kinase|serine/threonine-protein kinase Nek6

Position

9q33.3-q34.11

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.918C>A; p.T306T; 9:124350944-124350944

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.53A>C; p.H18P; 9:124302038-124302038

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.328G>A; p.E110K; 9:124321513-124321513

 skinmalignant_melanomaSubstitution - Missense

c.594C>T; p.H198H; 9:124327438-124327438

 skinmalignant_melanomaSubstitution - coding silent

c.384+1G>T; p.?; 9:124321570-124321570

 lungcarcinoma; adenocarcinomaUnknown

c.399G>C; p.Q133H; 9:124326344-124326344

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.873C>T; p.Y291Y; 9:124350899-124350899

 ovarycarcinoma; mucinous_carcinomaSubstitution - coding silent

c.873C>T; p.Y291Y; 9:124350899-124350899

 ovarycarcinoma; mucinous_carcinomaSubstitution - coding silent

c.261C>T; p.I87I; 9:124313973-124313973

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.555T>C; p.G185G; 9:124327399-124327399

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.371C>T; p.S124L; 9:124321556-124321556

 livercarcinomaSubstitution - Missense

c.371C>T; p.S124L; 9:124321556-124321556

 livercarcinomaSubstitution - Missense

c.586G>A; p.A196T; 9:124327430-124327430

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.529G>A; p.G177S; 9:124327373-124327373

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.531C>T; p.G177G; 9:124327375-124327375

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.97T>C; p.C33R; 9:124312536-124312536

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.194C>T; p.A65V; 9:124312633-124312633

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.102G>A; p.S34S; 9:124312541-124312541

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.534C>T; p.V178V; 9:124327378-124327378

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.466A>G; p.M156V; 9:124326411-124326411

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.803C>T; p.S268F; 9:124347815-124347815

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.535G>A; p.V179M; 9:124327379-124327379

 prostatecarcinomaSubstitution - Missense

c.833G>A; p.C278Y; 9:124350859-124350859

 skinmalignant_melanomaSubstitution - Missense

c.693C>A; p.Y231*; 9:124339662-124339662

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.137G>A; p.R46Q; 9:124312576-124312576

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.210+2T>C; p.?; 9:124312651-124312651

 livercarcinomaUnknown

c.295A>G; p.I99V; 9:124321480-124321480

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.295A>G; p.I99V; 9:124321480-124321480

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.776A>G; p.Y259C; 9:124347788-124347788

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.685C>G; p.L229V; 9:124339654-124339654

 breastcarcinomaSubstitution - Missense

c.861T>A; p.P287P; 9:124350887-124350887

 livercarcinomaSubstitution - coding silent

c.861T>A; p.P287P; 9:124350887-124350887

 livercarcinomaSubstitution - coding silent

c.364G>T; p.D122Y; 9:124321549-124321549

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.563G>A; p.R188H; 9:124327407-124327407

 breastcarcinomaSubstitution - Missense

c.45G>A; p.G15G; 9:124302030-124302030

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.538A>C; p.K180Q; 9:124327382-124327382

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.581C>A; p.T194N; 9:124327425-124327425

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.108G>A; p.A36A; 9:124312547-124312547

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.318C>T; p.I106I; 9:124321503-124321503

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.775T>A; p.Y259N; 9:124347787-124347787

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.318C>T; p.I106I; 9:124321503-124321503

 breastcarcinomaSubstitution - coding silent

c.735delG; p.M245fs*>62; 9:124347747-124347747

 skin; upper_legmalignant_melanomaDeletion - Frameshift

c.836T>C; p.I279T; 9:124350862-124350862

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.790G>A; p.G264R; 9:124347802-124347802

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.357C>T; p.D119D; 9:124321542-124321542

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.790G>A; p.G264R; 9:124347802-124347802

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.561C>T; p.G187G; 9:124327405-124327405

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.920G>A; p.*307*; 9:124350946-124350946

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.4C>T; p.P2S; 9:124301989-124301989

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.4C>T; p.P2S; 9:124301989-124301989

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.869G>A; p.G290E; 9:124350895-124350895

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.675C>T; p.S225S; 9:124339644-124339644

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.528G>A; p.T176T; 9:124327372-124327372

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.296T>G; p.I99S; 9:124321481-124321481

 kidneycarcinoma; renal_cell_carcinomaSubstitution - Missense

c.296T>G; p.I99S; 9:124321481-124321481

 kidneycarcinoma; renal_cell_carcinomaSubstitution - Missense

c.346G>C; p.E116Q; 9:124321531-124321531

 breastcarcinomaSubstitution - Missense

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