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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10653

Name

SPINT2

Synonymous

serine peptidase inhibitor, Kunitz type, 2;SPINT2;serine peptidase inhibitor, Kunitz type, 2

Definition

hepatocyte growth factor activator inhibitor type 2|kunitz-type protease inhibitor 2|placental bikunin|serine protease inhibitor, Kunitz type, 2

Position

19q13.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.481T>C; p.F161L; 19:38290208-38290208

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.714C>T; p.S238S; 19:38291961-38291961

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.615C>T; p.F205F; 19:38291862-38291862

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.215A>G; p.D72G; 19:38283735-38283735

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.205G>A; p.G69R; 19:38283725-38283725

 skinmalignant_melanomaSubstitution - Missense

c.143G>A; p.R48Q; 19:38283663-38283663

 skinmalignant_melanomaSubstitution - Missense

c.373G>A; p.D125N; 19:38289173-38289173

 skinmalignant_melanomaSubstitution - Missense

c.373G>A; p.D125N; 19:38289173-38289173

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.373G>A; p.D125N; 19:38289173-38289173

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.552C>T; p.F184F; 19:38290279-38290279

 skinmalignant_melanomaSubstitution - coding silent

c.580C>T; p.L194F; 19:38290563-38290563

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.665G>T; p.R222L; 19:38291912-38291912

 pancreascarcinomaSubstitution - Missense

c.442C>T; p.R148C; 19:38290169-38290169

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.142C>T; p.R48W; 19:38283662-38283662

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.457G>A; p.V153M; 19:38290184-38290184

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.568C>T; p.P190S; 19:38290551-38290551

 skin; neckmalignant_melanomaSubstitution - Missense

c.385T>G; p.Y129D; 19:38289185-38289185

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.309G>T; p.R103S; 19:38287907-38287907

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.553C>T; p.R185C; 19:38290280-38290280

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.240C>T; p.T80T; 19:38283760-38283760

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.521G>A; p.R174H; 19:38290248-38290248

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.317C>T; p.A106V; 19:38287915-38287915

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.598G>C; p.V200L; 19:38291845-38291845

 thyroidother; neoplasmSubstitution - Missense

c.598G>C; p.V200L; 19:38291845-38291845

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.583G>T; p.G195C; 19:38290566-38290566

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.653T>C; p.V218A; 19:38291900-38291900

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.653T>C; p.V218A; 19:38291900-38291900

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.173T>C; p.V58A; 19:38283693-38283693

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.23G>A; p.R8K; 19:38264915-38264915

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.351G>A; p.Q117Q; 19:38289151-38289151

 skinmalignant_melanomaSubstitution - coding silent

c.144G>T; p.R48R; 19:38283664-38283664

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.510G>T; p.K170N; 19:38290237-38290237

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.673C>T; p.R225W; 19:38291920-38291920

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.316G>T; p.A106S; 19:38287914-38287914

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.318G>A; p.A106A; 19:38287916-38287916

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.443G>A; p.R148H; 19:38290170-38290170

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.645C>T; p.A215A; 19:38291892-38291892

 skinmalignant_melanomaSubstitution - coding silent

c.553+1delG; p.?; 19:38290281-38290281

 large_intestine; rectumNSUnknown

c.379T>C; p.F127L; 19:38289179-38289179

 skinmalignant_melanomaSubstitution - Missense

c.379T>C; p.F127L; 19:38289179-38289179

 skinmalignant_melanomaSubstitution - Missense

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