Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10445

Name

MCRS1

Synonymous

microspherule protein 1;MCRS1;microspherule protein 1

Definition

58 kDa microspherule protein|INO80 complex subunit J|INO80 complex subunit Q|cell cycle-regulated factor (78 kDa)|cell cycle-regulated factor p78

Position

12q13.12

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.8G>A; p.R3H; 12:49566432-49566432

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1214-2A>G; p.?; 12:49558972-49558972

 pancreascarcinomaUnknown

c.1291C>T; p.P431S; 12:49558893-49558893

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1291C>T; p.P431S; 12:49558893-49558893

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1291C>T; p.P431S; 12:49558893-49558893

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1102C>T; p.R368W; 12:49559476-49559476

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.546G>T; p.R182R; 12:49564531-49564531

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1087C>T; p.R363W; 12:49559491-49559491

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1087C>T; p.R363W; 12:49559491-49559491

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.539C>T; p.T180I; 12:49564538-49564538

 skinmalignant_melanomaSubstitution - Missense

c.1389C>T; p.A463A; 12:49558682-49558682

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1395C>G; p.I465M; 12:49558676-49558676

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.186C>A; p.S62S; 12:49566079-49566079

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1130_1131CC>TT; p.T377I; 12:49559296-49559297

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.136C>T; p.R46*; 12:49566129-49566129

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1091G>A; p.G364D; 12:49559487-49559487

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1125+1G>T; p.?; 12:49559452-49559452

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.67G>C; p.D23H; 12:49566198-49566198

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.881T>A; p.F294Y; 12:49560334-49560334

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.544C>T; p.R182W; 12:49564533-49564533

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.544C>T; p.R182W; 12:49564533-49564533

 skinmalignant_melanomaSubstitution - Missense

c.1126-4_1126-3insC; p.?; 12:49559304-49559305

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.849G>A; p.Q283Q; 12:49560366-49560366

 livercarcinomaSubstitution - coding silent

c.849G>A; p.Q283Q; 12:49560366-49560366

 livercarcinomaSubstitution - coding silent

c.1380C>T; p.D460D; 12:49558691-49558691

 ovaryother; neoplasmSubstitution - coding silent

c.676G>A; p.E226K; 12:49563467-49563467

 breastcarcinomaSubstitution - Missense

c.197A>G; p.K66R; 12:49565659-49565659

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.197A>G; p.K66R; 12:49565659-49565659

 stomachadenocarcinomaSubstitution - Missense

c.928C>T; p.R310*; 12:49559960-49559960

 haematopoietic_and_lymphoid_tissue; spleenlymphoid_neoplasm; marginal_zone_lymphomaSubstitution - Nonsense

c.366A>G; p.P122P; 12:49564857-49564857

 livercarcinomaSubstitution - coding silent

c.651G>C; p.Q217H; 12:49563492-49563492

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.865_866insG; p.D289fs*8; 12:49560349-49560350

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeInsertion - Frameshift

c.208T>C; p.F70L; 12:49565648-49565648

 skinmalignant_melanomaSubstitution - Missense

c.1205G>A; p.R402Q; 12:49559222-49559222

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1042+1G>A; p.?; 12:49559728-49559728

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.112G>C; p.E38Q; 12:49566153-49566153

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1103G>A; p.R368Q; 12:49559475-49559475

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.188G>T; p.R63M; 12:49566077-49566077

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1126-3_1126-2insC; p.?; 12:49559303-49559304

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1034G>T; p.S345I; 12:49559737-49559737

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1402G>C; p.E468Q; 12:49558669-49558669

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1237G>A; p.G413S; 12:49558947-49558947

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.928C>G; p.R310G; 12:49559960-49559960

 breastcarcinomaSubstitution - Missense

c.308C>T; p.S103F; 12:49565548-49565548

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.32G>A; p.R11H; 12:49566408-49566408

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.720C>T; p.T240T; 12:49563125-49563125

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.593C>T; p.S198F; 12:49564484-49564484

 skinmalignant_melanomaSubstitution - Missense

c.738C>T; p.D246D; 12:49563107-49563107

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1281C>T; p.I427I; 12:49558903-49558903

 skinmalignant_melanomaSubstitution - coding silent

c.1042+3G>C; p.?; 12:49559726-49559726

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.391C>T; p.R131C; 12:49564832-49564832

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.705+7C>G; p.?; 12:49563431-49563431

 ovaryother; neoplasmUnknown

c.705+7C>G; p.?; 12:49563431-49563431

 ovaryother; neoplasmUnknown

c.1360G>A; p.V454I; 12:49558711-49558711

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.540C>T; p.T180T; 12:49564537-49564537

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.137G>A; p.R46Q; 12:49566128-49566128

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1267C>T; p.R423W; 12:49558917-49558917

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1267C>T; p.R423W; 12:49558917-49558917

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1267C>T; p.R423W; 12:49558917-49558917

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.287G>A; p.R96H; 12:49565569-49565569

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.210C>T; p.F70F; 12:49565646-49565646

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.210C>T; p.F70F; 12:49565646-49565646

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1245C>A; p.F415L; 12:49558939-49558939

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1120C>T; p.R374C; 12:49559458-49559458

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1406C>A; p.A469D; 12:49558665-49558665

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1121G>A; p.R374H; 12:49559457-49559457

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1264C>T; p.R422*; 12:49558920-49558920

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1264C>T; p.R422*; 12:49558920-49558920

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.1016_1017GG>AA; p.W339>?; 12:49559754-49559755

 large_intestine; coloncarcinoma; adenocarcinomaComplex

c.988C>T; p.R330W; 12:49559783-49559783

 skinmalignant_melanomaSubstitution - Missense

c.346A>G; p.T116A; 12:49564877-49564877

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.217G>T; p.E73*; 12:49565639-49565639

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.895G>C; p.D299H; 12:49560320-49560320

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.173_174GG>AA; p.R58Q; 12:49566091-49566092

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.842C>G; p.T281R; 12:49563003-49563003

 breastcarcinomaSubstitution - Missense

c.865_866insC; p.D289fs*8; 12:49560349-49560350

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeInsertion - Frameshift

c.704C>T; p.S235L; 12:49563439-49563439

 skinmalignant_melanomaSubstitution - Missense

c.340C>A; p.P114T; 12:49564883-49564883

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.238G>A; p.A80T; 12:49565618-49565618

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1042+1G>T; p.?; 12:49559728-49559728

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.1316G>A; p.R439H; 12:49558868-49558868

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

')