Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1017

Name

CDK2

Synonymous

cyclin-dependent kinase 2;CDK2;cyclin-dependent kinase 2

Definition

cdc2-related protein kinase|cell division protein kinase 2|p33 protein kinase

Position

12q13

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.889C>A; p.R297R; 12:55971617-55971617

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.373C>T; p.H125Y; 12:55968835-55968835

 skin; legmalignant_melanomaSubstitution - Missense

c.373C>T; p.H125Y; 12:55968835-55968835

 skin; legmalignant_melanomaSubstitution - Missense

c.266A>C; p.K89T; 12:55968120-55968120

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.367G>A; p.V123I; 12:55968829-55968829

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.779G>A; p.R260Q; 12:55971234-55971234

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.758C>T; p.P253L; 12:55971213-55971213

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.610C>A; p.P204T; 12:55971065-55971065

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.339G>T; p.Q113H; 12:55968801-55968801

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.234delG; p.V79fs*37; 12:55968088-55968088

 breastcarcinomaDeletion - Frameshift

c.448A>G; p.R150G; 12:55968910-55968910

 pancreascarcinomaSubstitution - Missense

c.353G>T; p.C118F; 12:55968815-55968815

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.523C>A; p.L175M; 12:55969511-55969511

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.361C>T; p.H121Y; 12:55968823-55968823

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.38G>A; p.G13D; 12:55967046-55967046

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.734G>A; p.R245Q; 12:55971189-55971189

 stomachcarcinomaSubstitution - Missense

c.846T>C; p.A282A; 12:55971574-55971574

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.37G>T; p.G13C; 12:55967045-55967045

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.519C>A; p.I173I; 12:55969507-55969507

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.364C>G; p.R122G; 12:55968826-55968826

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.733C>T; p.R245W; 12:55971188-55971188

 pancreascarcinomaSubstitution - Missense

c.371T>C; p.L124P; 12:55968833-55968833

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.135C>T; p.P45P; 12:55967875-55967875

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.845C>A; p.A282D; 12:55971573-55971573

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.365G>T; p.R122L; 12:55968827-55968827

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.134C>T; p.P45L; 12:55967874-55967874

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.134C>T; p.P45L; 12:55967874-55967874

 central_nervous_system; braingliomaSubstitution - Missense

c.134C>T; p.P45L; 12:55967874-55967874

 central_nervous_system; braingliomaSubstitution - Missense

c.134C>T; p.P45L; 12:55967874-55967874

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.37G>A; p.G13S; 12:55967045-55967045

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.37G>A; p.G13S; 12:55967045-55967045

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.609_610CC>TT; p.P204S; 12:55971064-55971065

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.552G>A; p.V184V; 12:55969540-55969540

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.552G>A; p.V184V; 12:55969540-55969540

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.58A>G; p.K20E; 12:55967066-55967066

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.327C>G; p.F109L; 12:55968789-55968789

 breastcarcinomaSubstitution - Missense

c.339G>A; p.Q113Q; 12:55968801-55968801

 livercarcinomaSubstitution - coding silent

c.339G>A; p.Q113Q; 12:55968801-55968801

 livercarcinomaSubstitution - coding silent

c.298C>T; p.P100S; 12:55968152-55968152

 NSmalignant_melanomaSubstitution - Missense

c.101A>C; p.K34T; 12:55967109-55967109

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.598C>T; p.R200W; 12:55971053-55971053

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.6G>T; p.E2D; 12:55967014-55967014

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.202G>A; p.D68N; 12:55968056-55968056

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.721C>T; p.P241S; 12:55971176-55971176

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.490G>T; p.V164L; 12:55969478-55969478

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.250C>T; p.H84Y; 12:55968104-55968104

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.720C>T; p.F240F; 12:55971175-55971175

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

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