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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10135

Name

NAMPT

Synonymous

nicotinamide phosphoribosyltransferase;NAMPT;nicotinamide phosphoribosyltransferase

Definition

NAmPRTase|pre-B cell-enhancing factor|pre-B-cell colony enhancing factor 1|pre-B-cell colony-enhancing factor 1

Position

7q22.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.824C>A; p.S275Y; 7:106263537-106263537

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.302G>A; p.W101*; 7:106274962-106274962

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.285C>A; p.V95V; 7:106274979-106274979

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.465C>T; p.S155S; 7:106269295-106269295

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1378A>G; p.T460A; 7:106251181-106251181

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1403C>T; p.T468I; 7:106251156-106251156

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1262C>G; p.P421R; 7:106253120-106253120

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.207delC; p.L70fs*1; 7:106277030-106277030

 skin; backmalignant_melanomaDeletion - Frameshift

c.318+1G>T; p.?; 7:106274945-106274945

 breastcarcinomaUnknown

c.727C>T; p.P243S; 7:106268480-106268480

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1142G>T; p.G381V; 7:106254452-106254452

 kidneyother; neoplasmSubstitution - Missense

c.391C>G; p.L131V; 7:106272586-106272586

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1304C>T; p.T435M; 7:106253078-106253078

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.1184T>A; p.L395*; 7:106254410-106254410

 skinmalignant_melanomaSubstitution - Nonsense

c.397A>C; p.T133P; 7:106272580-106272580

 breastcarcinomaSubstitution - Missense

c.393C>G; p.L131L; 7:106272584-106272584

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.589G>T; p.G197*; 7:106269171-106269171

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.267A>G; p.E89E; 7:106274997-106274997

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1268A>G; p.K423R; 7:106253114-106253114

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.699G>A; p.T233T; 7:106268508-106268508

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1079C>A; p.T360N; 7:106261598-106261598

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.879A>C; p.E293D; 7:106263482-106263482

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.787G>A; p.E263K; 7:106263574-106263574

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.787G>A; p.E263K; 7:106263574-106263574

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.318G>C; p.E106D; 7:106274946-106274946

 breastcarcinomaSubstitution - Missense

c.1348C>T; p.L450F; 7:106253034-106253034

 skinmalignant_melanomaSubstitution - Missense

c.360T>C; p.P120P; 7:106272617-106272617

 pancreascarcinomaSubstitution - coding silent

c.36C>T; p.L12L; 7:106284849-106284849

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1090-2A>G; p.?; 7:106254506-106254506

 prostatecarcinomaUnknown

c.526T>C; p.L176L; 7:106269234-106269234

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1025A>G; p.K342R; 7:106261652-106261652

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.526T>C; p.L176L; 7:106269234-106269234

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.231A>C; p.K77N; 7:106275033-106275033

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.208T>G; p.L70V; 7:106277029-106277029

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.583T>C; p.Y195H; 7:106269177-106269177

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1285C>T; p.R429*; 7:106253097-106253097

 breastcarcinomaSubstitution - Nonsense

c.1064G>A; p.G355E; 7:106261613-106261613

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.722C>T; p.S241F; 7:106268485-106268485

 breastcarcinomaSubstitution - Missense

c.276A>G; p.Q92Q; 7:106274988-106274988

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1152A>T; p.G384G; 7:106254442-106254442

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.686A>C; p.K229T; 7:106268521-106268521

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.754G>T; p.A252S; 7:106263607-106263607

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.754G>T; p.A252S; 7:106263607-106263607

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1066G>A; p.V356I; 7:106261611-106261611

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.16G>A; p.E6K; 7:106284869-106284869

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.401T>C; p.V134A; 7:106272576-106272576

 skinmalignant_melanomaSubstitution - Missense

c.777A>G; p.K259K; 7:106263584-106263584

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.777A>G; p.K259K; 7:106263584-106263584

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1294T>A; p.L432I; 7:106253088-106253088

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.550G>A; p.D184N; 7:106269210-106269210

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.571C>A; p.H191N; 7:106269189-106269189

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1015A>G; p.K339E; 7:106261662-106261662

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.205T>C; p.Y69H; 7:106277032-106277032

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.527T>C; p.L176S; 7:106269233-106269233

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.527T>C; p.L176S; 7:106269233-106269233

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.527T>C; p.L176S; 7:106269233-106269233

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1013C>G; p.S338*; 7:106261664-106261664

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.441G>C; p.W147C; 7:106272536-106272536

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.513A>G; p.I171M; 7:106269247-106269247

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1060G>A; p.D354N; 7:106261617-106261617

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.772G>T; p.E258*; 7:106263589-106263589

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.662T>C; p.V221A; 7:106268545-106268545

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1088A>C; p.E363A; 7:106261589-106261589

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.326A>G; p.D109G; 7:106272651-106272651

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1237G>C; p.V413L; 7:106253145-106253145

 breastcarcinomaSubstitution - Missense

c.131C>G; p.T44R; 7:106277106-106277106

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.425A>G; p.Y142C; 7:106272552-106272552

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.425A>G; p.Y142C; 7:106272552-106272552

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.622G>A; p.A208T; 7:106268585-106268585

 prostatecarcinomaSubstitution - Missense

c.857C>T; p.A286V; 7:106263504-106263504

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.870A>G; p.I290M; 7:106263491-106263491

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

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