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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10059

Name

DNM1L

Synonymous

dynamin 1-like;DNM1L;dynamin 1-like

Definition

Dnm1p/Vps1p-like protein|dynamin family member proline-rich carboxyl-terminal domain less|dynamin-1-like protein|dynamin-like protein 4|dynamin-like protein IV|dynamin-related protein 1

Position

12p11.21

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.547G>A; p.A183T; 12:32713299-32713299

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.547G>A; p.A183T; 12:32713299-32713299

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.547G>A; p.A183T; 12:32713299-32713299

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1915C>T; p.R639W; 12:32740439-32740439

 skin; anklemalignant_melanoma; acral_lentiginousSubstitution - Missense

c.1696G>T; p.E566*; 12:32738285-32738285

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1696G>T; p.E566*; 12:32738285-32738285

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1735G>A; p.D579N; 12:32740091-32740091

 skinmalignant_melanomaSubstitution - Missense

c.678C>T; p.A226A; 12:32718701-32718701

 skinmalignant_melanomaSubstitution - coding silent

c.56G>T; p.G19V; 12:32679419-32679419

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.56G>T; p.G19V; 12:32679419-32679419

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1456T>G; p.L486V; 12:32733724-32733724

 skinmalignant_melanomaSubstitution - Missense

c.1658C>T; p.A553V; 12:32737926-32737926

 kidneyother; neoplasmSubstitution - Missense

c.1201-2A>G; p.?; 12:32731354-32731354

 lungcarcinoma; adenocarcinomaUnknown

c.808C>T; p.Q270*; 12:32720731-32720731

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.120A>C; p.S40S; 12:32701432-32701432

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1127G>A; p.R376Q; 12:32731061-32731061

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.682G>C; p.D228H; 12:32718705-32718705

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.1598C>T; p.S533F; 12:32737866-32737866

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.658A>G; p.M220V; 12:32718681-32718681

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.695G>A; p.G232E; 12:32718718-32718718

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.21C>A; p.V7V; 12:32679384-32679384

 thyroidother; neoplasmSubstitution - coding silent

c.1633C>A; p.Q545K; 12:32737901-32737901

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.787C>T; p.R263C; 12:32720710-32720710

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.283C>T; p.H95Y; 12:32707399-32707399

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1647C>T; p.P549P; 12:32737915-32737915

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.371G>A; p.G124E; 12:32710930-32710930

 soft_tissue; blood_vesselangiosarcomaSubstitution - Missense

c.529C>A; p.P177T; 12:32713281-32713281

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.370G>A; p.G124R; 12:32710929-32710929

 soft_tissue; blood_vesselangiosarcomaSubstitution - Missense

c.1613G>A; p.S538N; 12:32737881-32737881

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.683A>G; p.D228G; 12:32718706-32718706

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.105C>T; p.S35S; 12:32701417-32701417

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.918A>G; p.T306T; 12:32722472-32722472

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2126G>A; p.R709H; 12:32742720-32742720

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1479T>C; p.Y493Y; 12:32733747-32733747

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1317G>T; p.M439I; 12:32731472-32731472

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1689C>G; p.S563R; 12:32738278-32738278

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.252G>A; p.G84G; 12:32707368-32707368

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1105A>G; p.I369V; 12:32731039-32731039

 oesophaguscarcinomaSubstitution - Missense

c.1073C>T; p.S358L; 12:32722627-32722627

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1171G>A; p.D391N; 12:32731105-32731105

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1715C>T; p.S572F; 12:32740071-32740071

 livercarcinomaSubstitution - Missense

c.1715C>T; p.S572F; 12:32740071-32740071

 livercarcinomaSubstitution - Missense

c.399G>T; p.K133N; 12:32710958-32710958

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.58G>A; p.A20T; 12:32679421-32679421

 livercarcinomaSubstitution - Missense

c.284A>G; p.H95R; 12:32707400-32707400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.855T>C; p.L285L; 12:32720778-32720778

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.848A>G; p.K283R; 12:32720771-32720771

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1452T>C; p.H484H; 12:32733720-32733720

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1208G>A; p.R403H; 12:32731363-32731363

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.1208G>A; p.R403H; 12:32731363-32731363

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1865C>T; p.A622V; 12:32740221-32740221

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1577C>T; p.S526L; 12:32737142-32737142

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1577C>T; p.S526L; 12:32737142-32737142

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1273G>C; p.E425Q; 12:32731428-32731428

 pancreasNSSubstitution - Missense

c.1992C>T; p.D664D; 12:32740516-32740516

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1187T>G; p.I396S; 12:32731121-32731121

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.905C>T; p.P302L; 12:32722459-32722459

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.966C>T; p.Y322Y; 12:32722520-32722520

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1588C>T; p.R530*; 12:32737153-32737153

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Nonsense

c.1977A>C; p.R659S; 12:32740501-32740501

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1977A>C; p.R659S; 12:32740501-32740501

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1577C>A; p.S526*; 12:32737142-32737142

 autonomic_ganglianeuroblastomaSubstitution - Nonsense

c.1771G>T; p.G591*; 12:32740127-32740127

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1446+2T>G; p.?; 12:32731945-32731945

 livercarcinomaUnknown

c.1446+2T>G; p.?; 12:32731945-32731945

 livercarcinomaUnknown

c.872G>T; p.R291M; 12:32720795-32720795

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2047C>T; p.Q683*; 12:32742641-32742641

 breastcarcinomaSubstitution - Nonsense

c.2125C>T; p.R709C; 12:32742719-32742719

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323G>A; p.R108Q; 12:32708178-32708178

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1418G>T; p.R473L; 12:32731915-32731915

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.665C>T; p.A222V; 12:32718688-32718688

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.590T>C; p.L197P; 12:32713342-32713342

 skinmalignant_melanomaSubstitution - Missense

c.369G>C; p.K123N; 12:32708224-32708224

 pancreascarcinomaSubstitution - Missense

c.369G>C; p.K123N; 12:32708224-32708224

 pancreascarcinomaSubstitution - Missense

c.401delT; p.S136fs*7; 12:32710960-32710960

 oesophagus; lower_thirdcarcinoma; adenocarcinomaDeletion - Frameshift

c.872+1G>C; p.?; 12:32720796-32720796

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.1135G>T; p.E379*; 12:32731069-32731069

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1255C>T; p.R419W; 12:32731410-32731410

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1508A>T; p.D503V; 12:32733776-32733776

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1892C>A; p.P631H; 12:32740416-32740416

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1327A>G; p.I443V; 12:32731482-32731482

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.666G>A; p.A222A; 12:32718689-32718689

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.708A>T; p.P236P; 12:32718731-32718731

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1367G>A; p.R456Q; 12:32731864-32731864

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1496C>T; p.P499L; 12:32733764-32733764

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.328G>T; p.E110*; 12:32708183-32708183

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1325T>C; p.I442T; 12:32731480-32731480

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.2100G>C; p.L700L; 12:32742694-32742694

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

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