| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10018 |
Name | BCL2L11 |
Synonymous | BCL2-like 11 (apoptosis facilitator);BCL2L11;BCL2-like 11 (apoptosis facilitator) |
Definition | bcl-2 interacting mediator of cell death|bcl-2 interacting protein Bim|bcl-2-like protein 11|bcl-2-related ovarian death agonist |
Position | 2q13 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.457C>T; p.R153W; 2:111150106-111150106 |
prostate | carcinoma | Substitution - Missense |
c.196C>T; p.P66S; 2:111123941-111123941 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.189G>A; p.P63P; 2:111123934-111123934 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.240_241insACA; p.F80_I81insT; 2:111123985-111123986 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - In frame |
c.272G>A; p.R91Q; 2:111124017-111124017 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.272G>A; p.R91Q; 2:111124017-111124017 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.250A>G; p.R84G; 2:111123995-111123995 |
breast | carcinoma | Substitution - Missense |
c.140A>G; p.N47S; 2:111123885-111123885 |
liver | carcinoma | Substitution - Missense |
c.254G>T; p.R85I; 2:111123999-111123999 |
lung; right_lower_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.335A>C; p.K112T; 2:111124080-111124080 |
liver | carcinoma | Substitution - Missense |
c.335A>C; p.K112T; 2:111124080-111124080 |
liver | carcinoma | Substitution - Missense |
c.145G>C; p.G49R; 2:111123890-111123890 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.312C>A; p.S104R; 2:111124057-111124057 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm | Substitution - Missense |
c.444C>T; p.I148I; 2:111150093-111150093 |
skin | malignant_melanoma | Substitution - coding silent |
c.466G>A; p.G156R; 2:111150115-111150115 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.151G>A; p.E51K; 2:111123896-111123896 |
breast | carcinoma | Substitution - Missense |
c.203C>T; p.A68V; 2:111123948-111123948 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.146G>A; p.G49E; 2:111123891-111123891 |
skin; mucosal | malignant_melanoma | Substitution - Missense |
c.458G>C; p.R153P; 2:111150107-111150107 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.458G>C; p.R153P; 2:111150107-111150107 |
breast | carcinoma | Substitution - Missense |
c.265C>T; p.L89L; 2:111124010-111124010 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.519_520insA; p.A174fs*>26; 2:111164153-111164154 |
prostate | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.519_520insA; p.A174fs*>26; 2:111164153-111164154 |
prostate | carcinoma | Insertion - Frameshift |
c.471C>T; p.D157D; 2:111150120-111150120 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.574C>T; p.R192C; 2:111164208-111164208 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.507G>A; p.L169L; 2:111164141-111164141 |
breast | carcinoma | Substitution - coding silent |
c.291C>G; p.F97L; 2:111124036-111124036 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.294delT; p.F99fs*10; 2:111124039-111124039 |
stomach | adenocarcinoma | Deletion - Frameshift |
c.95C>A; p.A32D; 2:111123840-111123840 |
peritoneum; appendix | other; pseudomyxoma_peritonei | Substitution - Missense |
c.251G>C; p.R84T; 2:111123996-111123996 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.95C>A; p.A32D; 2:111123840-111123840 |
thyroid | other; neoplasm | Substitution - Missense |
c.198A>C; p.P66P; 2:111123943-111123943 |
breast | carcinoma | Substitution - coding silent |
c.198A>C; p.P66P; 2:111123943-111123943 |
breast | carcinoma | Substitution - coding silent |
c.563G>T; p.R188L; 2:111164197-111164197 |
lung; right_lower_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.560_561insA; p.R188fs*>12; 2:111164194-111164195 |
endometrium | carcinoma; endometrioid_carcinoma | Insertion - Frameshift |
c.172G>A; p.G58S; 2:111123917-111123917 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.538C>T; p.R180*; 2:111164172-111164172 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.187C>T; p.P63S; 2:111123932-111123932 |
skin | malignant_melanoma | Substitution - Missense |
c.101_104delCCTC; p.S35fs*48; 2:111123846-111123849 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | Deletion - Frameshift |
c.563G>A; p.R188H; 2:111164197-111164197 |
pancreas | carcinoma | Substitution - Missense |
c.4G>A; p.A2T; 2:111123749-111123749 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.214C>T; p.P72S; 2:111123959-111123959 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.526G>A; p.E176K; 2:111164160-111164160 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.585G>C; p.W195C; 2:111164219-111164219 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.480C>T; p.N160N; 2:111150129-111150129 |
biliary_tract; bile_duct | carcinoma; adenocarcinoma | Substitution - coding silent |
c.230C>T; p.S77F; 2:111123975-111123975 |
skin | malignant_melanoma | Substitution - Missense |
c.62C>T; p.P21L; 2:111123807-111123807 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |