| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9978 |
Name | RBX1 |
Synonymous | ring-box 1, E3 ubiquitin protein ligase;RBX1;ring-box 1, E3 ubiquitin protein ligase |
Definition | E3 ubiquitin-protein ligase RBX1|RING box protein 1|RING finger protein 75|RING-box protein 1|ZYP protein|regulator of cullins 1 |
Position | 22q13.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
BTRC | CELL_MAP; |
in same component |
BTRC | REACTOME; |
in same component |
CUL1 | CELL_MAP; |
in same component |
CUL1 | REACTOME; |
in same component |
CUL2 | NCI_NATURE; |
in same component |
CUL5 | REACTOME; |
in same component |
HIF1A | NCI_NATURE; |
in same component |
NFKB1 | REACTOME; |
in same component |
SKP1 | CELL_MAP; |
in same component |
SKP1 | REACTOME; |
in same component |
SKP2 | CELL_MAP; |
in same component |
TCEB1 | NCI_NATURE; |
in same component |
TCEB1 | REACTOME; |
in same component |
TCEB2 | NCI_NATURE; |
in same component |
TCEB2 | REACTOME; |
in same component |
VHL | NCI_NATURE; |
interacts with |
ABTB2 | BIOGRID; |
interacts with |
ABTB2 | HPRD; |
interacts with |
ACTG1 | BIOGRID; |
interacts with |
AHR | HPRD; |
interacts with |
ARID1B | BIOGRID; |
interacts with |
CAND1 | BIOGRID; |
interacts with |
CAND1 | HPRD; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CCND1 | BIOGRID; |
interacts with |
CCND1 | HPRD; |
interacts with |
CCND2 | BIOGRID; |
interacts with |
CCND3 | BIOGRID; |
interacts with |
CDC34 | BIOGRID; |
interacts with |
CDC34 | HPRD; |
interacts with |
CKS1B | MINT; |
interacts with |
COPS6 | HPRD; |
interacts with |
CUL1 | BIOGRID; |
interacts with |
CUL1 | HPRD; |
interacts with |
CUL1 | MINT; |
interacts with |
CUL2 | BIOGRID; |
interacts with |
CUL2 | HPRD; |
interacts with |
CUL2 | MINT; |
interacts with |
CUL3 | BIOGRID; |
interacts with |
CUL3 | HPRD; |
interacts with |
CUL4A | BIOGRID; |
interacts with |
CUL4A | HPRD; |
interacts with |
CUL4B | BIOGRID; |
interacts with |
CUL4B | HPRD; |
interacts with |
CUL5 | BIOGRID; |
interacts with |
CUL5 | HPRD; |
interacts with |
CUL7 | BIOGRID; |
interacts with |
CUL7 | HPRD; |
interacts with |
DCUN1D1 | BIOGRID; |
interacts with |
DDB1 | BIOGRID; |
interacts with |
DDB1 | HPRD; |
interacts with |
DDB2 | BIOGRID; |
interacts with |
DET1 | BIOGRID; |
interacts with |
DIO2 | BIOGRID; |
interacts with |
E2F1 | BIOGRID; |
interacts with |
ENC1 | BIOGRID; |
interacts with |
FBXL12 | MINT; |
interacts with |
FBXO11 | BIOGRID; |
interacts with |
FBXO11 | HPRD; |
interacts with |
FBXO18 | BIOGRID; |
interacts with |
FBXO18 | HPRD; |
interacts with |
FBXO22 | BIOGRID; |
interacts with |
FBXO2 | HPRD; |
interacts with |
FBXO31 | BIOGRID; |
interacts with |
FBXO33 | HPRD; |
interacts with |
FBXO33 | MINT; |
interacts with |
FBXO3 | BIOGRID; |
interacts with |
FBXW11 | BIOGRID; |
interacts with |
FBXW8 | BIOGRID; |
interacts with |
FBXW8 | HPRD; |
interacts with |
GAN | BIOGRID; |
interacts with |
GPS1 | HPRD; |
interacts with |
HSPA8 | BIOGRID; |
interacts with |
KBTBD10 | BIOGRID; |
interacts with |
KEAP1 | BIOGRID; |
interacts with |
LRRC41 | HPRD; |
interacts with |
MED8 | HPRD; |
interacts with |
NCOA3 | BIOGRID; |
interacts with |
NEDD8 | BIOGRID; |
interacts with |
NEDD8 | HPRD; |
interacts with |
NEURL2 | HPRD; |
interacts with |
PGAM5 | BIOGRID; |
interacts with |
PSMA6 | BIOGRID; |
interacts with |
PTGS2 | BIOGRID; |
interacts with |
RELA | MINT; |
interacts with |
RFWD2 | BIOGRID; |
interacts with |
Rps6kb1 | BIOGRID; |
interacts with |
RPS6KB1 | BIOGRID; |
interacts with |
SKP1 | BIOGRID; |
interacts with |
SKP1 | HPRD; |
interacts with |
SKP1 | MINT; |
interacts with |
SKP2 | BIOGRID; |
interacts with |
SKP2 | MINT; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SOCS1 | MINT; |
interacts with |
TBL3 | HPRD; |
interacts with |
TCEB1 | HPRD; |
interacts with |
TCEB1 | MINT; |
interacts with |
TCEB2 | BIOGRID; |
interacts with |
TCEB2 | HPRD; |
interacts with |
TCEB2 | MINT; |
interacts with |
TCEB3 | HPRD; |
interacts with |
VHL | BIOGRID; |
interacts with |
VHL | HPRD; |
interacts with |
WSB1 | HPRD; |
interacts with |
ZC3HC1 | BIOGRID; |
Metabolic Interaction [Top] | ||
There is no record for RBX1 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
BTRC | CELL_MAP; |
reacts with |
BTRC | REACTOME; |
reacts with |
CUL1 | CELL_MAP; |
reacts with |
CUL1 | REACTOME; |
reacts with |
CUL2 | NCI_NATURE; |
reacts with |
CUL5 | REACTOME; |
reacts with |
HIF1A | NCI_NATURE; |
reacts with |
NFKB1 | REACTOME; |
reacts with |
RBX1 | CELL_MAP; |
reacts with |
RBX1 | NCI_NATURE; |
reacts with |
RBX1 | REACTOME; |
reacts with |
SKP1 | CELL_MAP; |
reacts with |
SKP1 | REACTOME; |
reacts with |
TCEB1 | NCI_NATURE; |
reacts with |
TCEB1 | REACTOME; |
reacts with |
TCEB2 | NCI_NATURE; |
reacts with |
TCEB2 | REACTOME; |
reacts with |
VHL | NCI_NATURE; |
state change |
BTRC | REACTOME; |
state change |
CUL1 | REACTOME; |
state change |
CUL5 | REACTOME; |
state change |
RBX1 | REACTOME; |
state change |
SKP1 | REACTOME; |
state change |
TCEB1 | REACTOME; |
state change |
TCEB2 | REACTOME; |