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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

7124

Name

TNF

Synonymous

tumor necrosis factor;TNF;tumor necrosis factor

Definition

APC1 protein|TNF, macrophage-derived|TNF, monocyte-derived|TNF-a|cachectin|tumor necrosis factor ligand superfamily member 2|tumor necrosis factor-alpha

Position

6p21.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 BAG4NCI_NATURE;

in same component

 BIRC2NCI_NATURE;

in same component

 BIRC3NCI_NATURE;

in same component

 CASP2NCI_NATURE;

in same component

 CRADDNCI_NATURE;

in same component

 FADDNCI_NATURE;

in same component

 MADDNCI_NATURE;

in same component

 MAP3K3NCI_NATURE;

in same component

 MAP3K5NCI_NATURE;

in same component

 MAP3K7NCI_NATURE;

in same component

 NSMAFNCI_NATURE;

in same component

 PIDDNCI_NATURE;

in same component

 RIPK1NCI_NATURE;

in same component

 RIPK1REACTOME;

in same component

 SMPD2NCI_NATURE;

in same component

 SQSTM1NCI_NATURE;

in same component

 STAT1NCI_NATURE;

in same component

 TNFRSF1ANCI_NATURE;

in same component

 TNFRSF1AREACTOME;

in same component

 TNFRSF1BNCI_NATURE;

in same component

 TRADDNCI_NATURE;

in same component

 TRADDREACTOME;

in same component

 TRAF1NCI_NATURE;

in same component

 TRAF2NCI_NATURE;

in same component

 TRAF2REACTOME;

interacts with

 ADAM17HPRD;

interacts with

 ADAM9HPRD;

interacts with

 BGNBIOGRID;

interacts with

 BGNHPRD;

interacts with

 BIRC2BIOGRID;

interacts with

 BTRCBIOGRID;

interacts with

 CAV1BIOGRID;

interacts with

 CDC42BIOGRID;

interacts with

 CHUKBIOGRID;

interacts with

 CSF1HPRD;

interacts with

 DCNBIOGRID;

interacts with

 FASBIOGRID;

interacts with

 FBXW11BIOGRID;

interacts with

 IFNGHPRD;

interacts with

 IKBKBBIOGRID;

interacts with

 IKBKGBIOGRID;

interacts with

 MAP3K7BIOGRID;

interacts with

 MMP17HPRD;

interacts with

 PDIK1LHPRD;

interacts with

 POU2F1BIOGRID;

interacts with

 PRTN3HPRD;

interacts with

 RALBP1BIOGRID;

interacts with

 RBCK1BIOGRID;

interacts with

 RIPK1BIOGRID;

interacts with

 RNF31BIOGRID;

interacts with

 TAB1BIOGRID;

interacts with

 TAB2BIOGRID;

interacts with

 TBK1BIOGRID;

interacts with

 TNFRSF1ABIOGRID;

interacts with

 TNFRSF1ACELL_MAP;

interacts with

 TNFRSF1AHPRD;

interacts with

 TNFRSF1AMINT;

interacts with

 TNFRSF1BBIOGRID;

interacts with

 TNFRSF1BCELL_MAP;

interacts with

 TNFRSF1BHPRD;

interacts with

 TNFRSF1BMINT;

interacts with

 TNIP1BIOGRID;

interacts with

 TRADDBIOGRID;

interacts with

 TRAF2BIOGRID;

interacts with

 TRAF2HPRD;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 EGR1NCI_NATURE;

metabolic catalysis

 EGR4NCI_NATURE;

metabolic catalysis

 IL12BNCI_NATURE;

metabolic catalysis

 IL12RB1NCI_NATURE;

metabolic catalysis

 IL23ANCI_NATURE;

metabolic catalysis

 IL23RNCI_NATURE;

metabolic catalysis

 JAK2NCI_NATURE;

metabolic catalysis

 NFKB1NCI_NATURE;

metabolic catalysis

 PRKCQNCI_NATURE;

metabolic catalysis

 TYK2NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 BAG4NCI_NATURE;

reacts with

 BIRC2NCI_NATURE;

reacts with

 BIRC3NCI_NATURE;

reacts with

 CASP2NCI_NATURE;

reacts with

 CRADDNCI_NATURE;

reacts with

 FADDNCI_NATURE;

reacts with

 MADDNCI_NATURE;

reacts with

 MAP3K3NCI_NATURE;

reacts with

 MAP3K5NCI_NATURE;

reacts with

 MAP3K7NCI_NATURE;

reacts with

 NSMAFNCI_NATURE;

reacts with

 RIPK1NCI_NATURE;

reacts with

 RIPK1REACTOME;

reacts with

 SMPD2NCI_NATURE;

reacts with

 SQSTM1NCI_NATURE;

reacts with

 STAT1NCI_NATURE;

reacts with

 TNFRSF1ANCI_NATURE;

reacts with

 TNFRSF1AREACTOME;

reacts with

 TNFRSF1BNCI_NATURE;

reacts with

 TNFNCI_NATURE;

reacts with

 TNFREACTOME;

reacts with

 TRADDNCI_NATURE;

reacts with

 TRADDREACTOME;

reacts with

 TRAF1NCI_NATURE;

reacts with

 TRAF2NCI_NATURE;

reacts with

 TRAF2REACTOME;

state change

 ADAM17NCI_NATURE;

state change

 CAV1NCI_NATURE;

state change

 CYLDNCI_NATURE;

state change

 RFFLNCI_NATURE;

state change

 STAT1NCI_NATURE;

state change

 TNFAIP3NCI_NATURE;

state change

 TNFRSF1ANCI_NATURE;

state change

 TNFNCI_NATURE;

state change

 TRADDNCI_NATURE;

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