| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7015 |
Name | TERT |
Synonymous | telomerase reverse transcriptase;TERT;telomerase reverse transcriptase |
Definition | telomerase catalytic subunit|telomerase-associated protein 2 |
Position | 5p15.33 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ABL1 | NCI_NATURE; |
in same component |
AKT1 | NCI_NATURE; |
in same component |
DKC1 | NCI_NATURE; |
in same component |
DKC1 | REACTOME; |
in same component |
HNRNPC | NCI_NATURE; |
in same component |
HSP90AA1 | NCI_NATURE; |
in same component |
HUS1 | NCI_NATURE; |
in same component |
MTOR | NCI_NATURE; |
in same component |
NCL | NCI_NATURE; |
in same component |
NFKB1 | NCI_NATURE; |
in same component |
PINX1 | NCI_NATURE; |
in same component |
PTGES3 | NCI_NATURE; |
in same component |
RAD1 | NCI_NATURE; |
in same component |
RAD9A | NCI_NATURE; |
in same component |
RPS6KB1 | NCI_NATURE; |
in same component |
SMG5 | NCI_NATURE; |
in same component |
SMG6 | NCI_NATURE; |
in same component |
XRCC5 | NCI_NATURE; |
in same component |
XRCC6 | NCI_NATURE; |
in same component |
YWHAE | NCI_NATURE; |
interacts with |
AKT1 | BIOGRID; |
interacts with |
AKT1 | HPRD; |
interacts with |
AKT1 | MINT; |
interacts with |
CIB1 | HPRD; |
interacts with |
HSP90AA1 | BIOGRID; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
MCRS1 | BIOGRID; |
interacts with |
MCRS1 | HPRD; |
interacts with |
MKRN1 | BIOGRID; |
interacts with |
MTOR | BIOGRID; |
interacts with |
MTOR | HPRD; |
interacts with |
NAT10 | BIOGRID; |
interacts with |
NCL | BIOGRID; |
interacts with |
PINX1 | BIOGRID; |
interacts with |
PINX1 | HPRD; |
interacts with |
PRKCA | HPRD; |
interacts with |
PTGES3 | BIOGRID; |
interacts with |
PTGES3 | HPRD; |
interacts with |
RELA | BIOGRID; |
interacts with |
RELA | HPRD; |
interacts with |
RPS6KB1 | BIOGRID; |
interacts with |
RPS6KB1 | HPRD; |
interacts with |
RUVBL1 | HPRD; |
interacts with |
RUVBL2 | HPRD; |
interacts with |
SMG5 | BIOGRID; |
interacts with |
SMG5 | HPRD; |
interacts with |
SMG6 | BIOGRID; |
interacts with |
SMG6 | HPRD; |
interacts with |
SRC | HPRD; |
interacts with |
TEP1 | BIOGRID; |
interacts with |
TEP1 | HPRD; |
interacts with |
TPP1 | HPRD; |
interacts with |
XPO1 | HPRD; |
interacts with |
XRCC5 | BIOGRID; |
interacts with |
XRCC5 | HPRD; |
interacts with |
XRCC6 | BIOGRID; |
interacts with |
XRCC6 | HPRD; |
interacts with |
YWHAQ | BIOGRID; |
interacts with |
YWHAQ | HPRD; |
interacts with |
YWHAZ | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
AKT1 | NCI_NATURE; |
metabolic catalysis |
ARNT | NCI_NATURE; |
metabolic catalysis |
E2F1 | NCI_NATURE; |
metabolic catalysis |
EGFR | NCI_NATURE; |
metabolic catalysis |
EGF | NCI_NATURE; |
metabolic catalysis |
FOS | NCI_NATURE; |
metabolic catalysis |
HDAC1 | NCI_NATURE; |
metabolic catalysis |
HDAC2 | NCI_NATURE; |
metabolic catalysis |
HIF1A | NCI_NATURE; |
metabolic catalysis |
IFNAR2 | NCI_NATURE; |
metabolic catalysis |
IFNG | NCI_NATURE; |
metabolic catalysis |
IL2 | NCI_NATURE; |
metabolic catalysis |
IRF1 | NCI_NATURE; |
metabolic catalysis |
JUN | NCI_NATURE; |
metabolic catalysis |
KAT2A | NCI_NATURE; |
metabolic catalysis |
MAX | NCI_NATURE; |
metabolic catalysis |
MXD1 | NCI_NATURE; |
metabolic catalysis |
MYC | NCI_NATURE; |
metabolic catalysis |
NR2F2 | NCI_NATURE; |
metabolic catalysis |
RBBP4 | NCI_NATURE; |
metabolic catalysis |
RBBP7 | NCI_NATURE; |
metabolic catalysis |
SAP18 | NCI_NATURE; |
metabolic catalysis |
SAP30 | NCI_NATURE; |
metabolic catalysis |
SIN3A | NCI_NATURE; |
metabolic catalysis |
SIN3B | NCI_NATURE; |
metabolic catalysis |
SP1 | NCI_NATURE; |
metabolic catalysis |
SP3 | NCI_NATURE; |
metabolic catalysis |
SUPT3H | NCI_NATURE; |
metabolic catalysis |
SUPT7L | NCI_NATURE; |
metabolic catalysis |
TAF10 | NCI_NATURE; |
metabolic catalysis |
TAF12 | NCI_NATURE; |
metabolic catalysis |
TAF9 | NCI_NATURE; |
metabolic catalysis |
TRRAP | NCI_NATURE; |
metabolic catalysis |
UBE3A | NCI_NATURE; |
metabolic catalysis |
WT1 | NCI_NATURE; |
sequential catalysis |
TERT | HUMANCYC; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ABL1 | NCI_NATURE; |
reacts with |
AKT1 | NCI_NATURE; |
reacts with |
CTNNB1 | NCI_NATURE; |
reacts with |
DKC1 | NCI_NATURE; |
reacts with |
DKC1 | REACTOME; |
reacts with |
HNRNPC | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
HUS1 | NCI_NATURE; |
reacts with |
MTOR | NCI_NATURE; |
reacts with |
NCL | NCI_NATURE; |
reacts with |
NFKB1 | NCI_NATURE; |
reacts with |
PINX1 | NCI_NATURE; |
reacts with |
PTGES3 | NCI_NATURE; |
reacts with |
RAD1 | NCI_NATURE; |
reacts with |
RAD9A | NCI_NATURE; |
reacts with |
RPS6KB1 | NCI_NATURE; |
reacts with |
SMARCA4 | NCI_NATURE; |
reacts with |
SMG5 | NCI_NATURE; |
reacts with |
SMG6 | NCI_NATURE; |
reacts with |
TCF7L1 | NCI_NATURE; |
reacts with |
TERT | NCI_NATURE; |
reacts with |
TERT | REACTOME; |
reacts with |
XRCC5 | NCI_NATURE; |
reacts with |
XRCC6 | NCI_NATURE; |
reacts with |
YWHAE | NCI_NATURE; |
state change |
AKT1 | NCI_NATURE; |
state change |
DKC1 | REACTOME; |
state change |
IL2 | NCI_NATURE; |
state change |
NHP2 | REACTOME; |
state change |
RUVBL1 | REACTOME; |
state change |
RUVBL2 | REACTOME; |
state change |
TERT | REACTOME; |
state change |
UBE3A | NCI_NATURE; |
state change |
WRAP53 | REACTOME; |