| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6667 |
Name | SP1 |
Synonymous | Sp1 transcription factor;SP1;Sp1 transcription factor |
Definition | specificity protein 1|transcription factor Sp1 |
Position | 12q13.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ARNT | NCI_NATURE; |
in same component |
EP300 | NCI_NATURE; |
in same component |
FOSL1 | NCI_NATURE; |
in same component |
HDAC2 | NCI_NATURE; |
in same component |
HIF1A | NCI_NATURE; |
in same component |
JUNB | NCI_NATURE; |
in same component |
JUND | NCI_NATURE; |
in same component |
SMAD4 | NCI_NATURE; |
in same component |
TP53 | NCI_NATURE; |
in same component |
ZBTB17 | NCI_NATURE; |
interacts with |
AATF | BIOGRID; |
interacts with |
AATF | HPRD; |
interacts with |
AATF | MINT; |
interacts with |
ABL1 | MINT; |
interacts with |
AHR | BIOGRID; |
interacts with |
AHR | HPRD; |
interacts with |
ARNT | BIOGRID; |
interacts with |
AR | BIOGRID; |
interacts with |
AR | CELL_MAP; |
interacts with |
AR | HPRD; |
interacts with |
ATF7IP2 | BIOGRID; |
interacts with |
ATF7IP2 | HPRD; |
interacts with |
ATF7IP | BIOGRID; |
interacts with |
BCL11B | BIOGRID; |
interacts with |
BCOR | BIOGRID; |
interacts with |
BCOR | HPRD; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
BRCA2 | BIOGRID; |
interacts with |
CASP3 | HPRD; |
interacts with |
CBX5 | BIOGRID; |
interacts with |
CCNA1 | BIOGRID; |
interacts with |
CCNA2 | BIOGRID; |
interacts with |
CCND1 | HPRD; |
interacts with |
CD2 | HPRD; |
interacts with |
CDK2 | BIOGRID; |
interacts with |
CDK4 | BIOGRID; |
interacts with |
CEBPB | BIOGRID; |
interacts with |
CEBPB | HPRD; |
interacts with |
CREBBP | BIOGRID; |
interacts with |
CRK | MINT; |
interacts with |
CRX | BIOGRID; |
interacts with |
CSNK2A1 | HPRD; |
interacts with |
CTBP1 | BIOGRID; |
interacts with |
CTCFL | BIOGRID; |
interacts with |
DCAF6 | BIOGRID; |
interacts with |
DNMT1 | BIOGRID; |
interacts with |
DROSHA | HPRD; |
interacts with |
E2F1 | BIOGRID; |
interacts with |
E2F1 | HPRD; |
interacts with |
E2F2 | HPRD; |
interacts with |
EGR1 | BIOGRID; |
interacts with |
EGR1 | HPRD; |
interacts with |
EGR1 | MINT; |
interacts with |
ELF1 | BIOGRID; |
interacts with |
ELF1 | HPRD; |
interacts with |
EP300 | BIOGRID; |
interacts with |
EP300 | HPRD; |
interacts with |
EPAS1 | MINT; |
interacts with |
ESR1 | BIOGRID; |
interacts with |
ESR1 | HPRD; |
interacts with |
ESR2 | BIOGRID; |
interacts with |
ESR2 | HPRD; |
interacts with |
ESRRA | BIOGRID; |
interacts with |
ESRRG | BIOGRID; |
interacts with |
ETS1 | CELL_MAP; |
interacts with |
ETS1 | HPRD; |
interacts with |
FYN | MINT; |
interacts with |
GABPA | BIOGRID; |
interacts with |
GABPA | HPRD; |
interacts with |
GABPA | MINT; |
interacts with |
GATA1 | BIOGRID; |
interacts with |
GATA3 | BIOGRID; |
interacts with |
GATA4 | BIOGRID; |
interacts with |
GATA6 | BIOGRID; |
interacts with |
HBZ | BIOGRID; |
interacts with |
HCFC1 | BIOGRID; |
interacts with |
HCFC1 | HPRD; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HDAC1 | MINT; |
interacts with |
HDAC2 | BIOGRID; |
interacts with |
HDAC2 | HPRD; |
interacts with |
HDAC3 | BIOGRID; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HIF1A | HPRD; |
interacts with |
HIF1A | MINT; |
interacts with |
HMGA1 | BIOGRID; |
interacts with |
HMGA1 | HPRD; |
interacts with |
HMGA1 | MINT; |
interacts with |
HNF4A | BIOGRID; |
interacts with |
HNF4A | HPRD; |
interacts with |
HOXC11 | BIOGRID; |
interacts with |
HSP90AA1 | BIOGRID; |
interacts with |
HSPA8 | HPRD; |
interacts with |
HTT | BIOGRID; |
interacts with |
HTT | HPRD; |
interacts with |
HTT | MINT; |
interacts with |
JUN | BIOGRID; |
interacts with |
JUN | CELL_MAP; |
interacts with |
JUN | HPRD; |
interacts with |
KLF10 | BIOGRID; |
interacts with |
KLF10 | HPRD; |
interacts with |
KLF4 | BIOGRID; |
interacts with |
KLF4 | HPRD; |
interacts with |
KLF6 | BIOGRID; |
interacts with |
KLF6 | HPRD; |
interacts with |
LDB1 | BIOGRID; |
interacts with |
LMO2 | BIOGRID; |
interacts with |
MAPK14 | BIOGRID; |
interacts with |
MAPK1 | HPRD; |
interacts with |
MAPK3 | HPRD; |
interacts with |
MECP2 | BIOGRID; |
interacts with |
MEF2C | BIOGRID; |
interacts with |
MEF2C | HPRD; |
interacts with |
MEF2D | BIOGRID; |
interacts with |
MEF2D | HPRD; |
interacts with |
MIS18BP1 | HPRD; |
interacts with |
MSX1 | BIOGRID; |
interacts with |
MSX1 | HPRD; |
interacts with |
MYC | BIOGRID; |
interacts with |
MYC | HPRD; |
interacts with |
MYOD1 | BIOGRID; |
interacts with |
MYOD1 | HPRD; |
interacts with |
MYOG | BIOGRID; |
interacts with |
MYOG | HPRD; |
interacts with |
NCK1 | MINT; |
interacts with |
NCL | BIOGRID; |
interacts with |
NCOR1 | BIOGRID; |
interacts with |
NCOR1 | HPRD; |
interacts with |
NCOR2 | BIOGRID; |
interacts with |
NCOR2 | HPRD; |
interacts with |
NFKB1 | BIOGRID; |
interacts with |
NFKB2 | BIOGRID; |
interacts with |
NFYA | HPRD; |
interacts with |
NFYB | BIOGRID; |
interacts with |
NFYB | HPRD; |
interacts with |
NFYC | BIOGRID; |
interacts with |
NFYC | INTACT; |
interacts with |
NKX3-1 | BIOGRID; |
interacts with |
NOS3 | HPRD; |
interacts with |
NR2E1 | BIOGRID; |
interacts with |
NR2F1 | BIOGRID; |
interacts with |
NR2F1 | HPRD; |
interacts with |
NR5A1 | BIOGRID; |
interacts with |
NR5A1 | HPRD; |
interacts with |
OGT | HPRD; |
interacts with |
PARP1 | BIOGRID; |
interacts with |
PER3 | HPRD; |
interacts with |
PFDN5 | BIOGRID; |
interacts with |
PGR | BIOGRID; |
interacts with |
PHOX2A | BIOGRID; |
interacts with |
POGZ | BIOGRID; |
interacts with |
POGZ | HPRD; |
interacts with |
POU2F1 | BIOGRID; |
interacts with |
POU2F1 | HPRD; |
interacts with |
POU2F1 | MINT; |
interacts with |
PPARG | BIOGRID; |
interacts with |
PPP1R13L | BIOGRID; |
interacts with |
PPP1R13L | HPRD; |
interacts with |
PRKCZ | BIOGRID; |
interacts with |
PRKDC | HPRD; |
interacts with |
PSIP1 | BIOGRID; |
interacts with |
PSMC5 | BIOGRID; |
interacts with |
PSMC5 | HPRD; |
interacts with |
PURA | BIOGRID; |
interacts with |
PURA | HPRD; |
interacts with |
RAD51 | BIOGRID; |
interacts with |
RARA | BIOGRID; |
interacts with |
RB1 | BIOGRID; |
interacts with |
RB1 | HPRD; |
interacts with |
RBBP4 | BIOGRID; |
interacts with |
RBBP4 | HPRD; |
interacts with |
RBL1 | HPRD; |
interacts with |
RELA | BIOGRID; |
interacts with |
RELA | HPRD; |
interacts with |
REL | BIOGRID; |
interacts with |
REL | HPRD; |
interacts with |
REST | BIOGRID; |
interacts with |
RNF4 | BIOGRID; |
interacts with |
RXRA | BIOGRID; |
interacts with |
SF3A1 | HPRD; |
interacts with |
SFPQ | BIOGRID; |
interacts with |
SHC1 | HPRD; |
interacts with |
SIN3A | BIOGRID; |
interacts with |
SKIV2L2 | HPRD; |
interacts with |
SKP2 | BIOGRID; |
interacts with |
SMAD2 | BIOGRID; |
interacts with |
SMAD2 | CELL_MAP; |
interacts with |
SMAD2 | HPRD; |
interacts with |
SMAD4 | BIOGRID; |
interacts with |
SMAD4 | CELL_MAP; |
interacts with |
SMAD4 | HPRD; |
interacts with |
SMARCA4 | BIOGRID; |
interacts with |
SMARCC1 | BIOGRID; |
interacts with |
SOX10 | HPRD; |
interacts with |
SOX8 | HPRD; |
interacts with |
SP3 | BIOGRID; |
interacts with |
SP3 | HPRD; |
interacts with |
SP4 | HPRD; |
interacts with |
SRC | MINT; |
interacts with |
SREBF1 | BIOGRID; |
interacts with |
SREBF1 | HPRD; |
interacts with |
SREBF2 | BIOGRID; |
interacts with |
SREBF2 | HPRD; |
interacts with |
SREBF2 | INTACT; |
interacts with |
SRF | BIOGRID; |
interacts with |
SRY | BIOGRID; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
SUB1 | BIOGRID; |
interacts with |
SYK | BIOGRID; |
interacts with |
TAF4 | BIOGRID; |
interacts with |
TAF4 | HPRD; |
interacts with |
TAL1 | BIOGRID; |
interacts with |
TAL1 | HPRD; |
interacts with |
TBP | HPRD; |
interacts with |
TBX21 | BIOGRID; |
interacts with |
TLX3 | BIOGRID; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TP53 | MINT; |
interacts with |
VHL | HPRD; |
interacts with |
YY1 | BIOGRID; |
interacts with |
YY1 | HPRD; |
interacts with |
ZBTB16 | HPRD; |
interacts with |
ZBTB7A | BIOGRID; |
interacts with |
ZBTB7A | HPRD; |
interacts with |
ZBTB7B | BIOGRID; |
Metabolic Interaction [Top] | ||
There is no record for SP1 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ARNT | NCI_NATURE; |
reacts with |
EP300 | NCI_NATURE; |
reacts with |
FOSL1 | NCI_NATURE; |
reacts with |
HIF1A | NCI_NATURE; |
reacts with |
JUNB | NCI_NATURE; |
reacts with |
JUND | NCI_NATURE; |
reacts with |
SMAD4 | NCI_NATURE; |
reacts with |
SP1 | NCI_NATURE; |
reacts with |
TP53 | NCI_NATURE; |
reacts with |
ZBTB17 | NCI_NATURE; |