| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 595 |
Name | CCND1 |
Synonymous | cyclin D1;CCND1;cyclin D1 |
Definition | B-cell CLL/lymphoma 1|B-cell lymphoma 1 protein|BCL-1 oncogene|G1/S-specific cyclin-D1|PRAD1 oncogene |
Position | 11q13 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
AR | NCI_NATURE; |
in same component |
CDK4 | CELL_MAP; |
in same component |
CDK4 | NCI_NATURE; |
in same component |
CDK4 | REACTOME; |
in same component |
CDK6 | CELL_MAP; |
in same component |
CDK6 | NCI_NATURE; |
in same component |
MYB | NCI_NATURE; |
interacts with |
AKAP8 | BIOGRID; |
interacts with |
AR | BIOGRID; |
interacts with |
AR | CELL_MAP; |
interacts with |
AR | HPRD; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
CCNDBP1 | BIOGRID; |
interacts with |
CCNDBP1 | HPRD; |
interacts with |
CDK2 | HPRD; |
interacts with |
CDK4 | BIOGRID; |
interacts with |
CDK4 | HPRD; |
interacts with |
Cdk4 | MINT; |
interacts with |
CDK4 | MINT; |
interacts with |
CDK6 | BIOGRID; |
interacts with |
CDK6 | HPRD; |
interacts with |
CDK6 | MINT; |
interacts with |
CDKN1A | BIOGRID; |
interacts with |
CDKN1A | HPRD; |
interacts with |
CDKN1A | MINT; |
interacts with |
CDKN1B | BIOGRID; |
interacts with |
CDKN1B | HPRD; |
interacts with |
CDKN1C | BIOGRID; |
interacts with |
CDKN2A | BIOGRID; |
interacts with |
CDKN2D | HPRD; |
interacts with |
CRYAB | BIOGRID; |
interacts with |
CTNNB1 | HPRD; |
interacts with |
CUL1 | BIOGRID; |
interacts with |
CUL3 | HPRD; |
interacts with |
CUL7 | BIOGRID; |
interacts with |
DMTF1 | HPRD; |
interacts with |
EP300 | BIOGRID; |
interacts with |
EP300 | HPRD; |
interacts with |
ESR1 | BIOGRID; |
interacts with |
ESR1 | HPRD; |
interacts with |
FBXO4 | BIOGRID; |
interacts with |
FBXW8 | BIOGRID; |
interacts with |
GLIS2 | HPRD; |
interacts with |
GSK3B | HPRD; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HDAC2 | BIOGRID; |
interacts with |
HDAC3 | BIOGRID; |
interacts with |
HDAC3 | HPRD; |
interacts with |
HERC5 | BIOGRID; |
interacts with |
HERC5 | HPRD; |
interacts with |
HSPA8 | BIOGRID; |
interacts with |
INSM1 | BIOGRID; |
interacts with |
INSM1 | HPRD; |
interacts with |
KAT2B | BIOGRID; |
interacts with |
KAT2B | HPRD; |
interacts with |
MAPK11 | BIOGRID; |
interacts with |
MAPK1 | BIOGRID; |
interacts with |
MCM10 | HPRD; |
interacts with |
MCM10 | MINT; |
interacts with |
Mybl2 | BIOGRID; |
interacts with |
MYBL2 | HPRD; |
interacts with |
NCOA1 | BIOGRID; |
interacts with |
NCOA1 | HPRD; |
interacts with |
NCOA3 | BIOGRID; |
interacts with |
NCOA3 | HPRD; |
interacts with |
NEUROD1 | BIOGRID; |
interacts with |
NEUROD1 | HPRD; |
interacts with |
NPDC1 | BIOGRID; |
interacts with |
NPDC1 | HPRD; |
interacts with |
Oaz1 | BIOGRID; |
interacts with |
ORC4 | HPRD; |
interacts with |
ORC4 | MINT; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
PRKACA | HPRD; |
interacts with |
PRMT5 | BIOGRID; |
interacts with |
RB1 | BIOGRID; |
interacts with |
RB1 | HPRD; |
interacts with |
RBL1 | HPRD; |
interacts with |
RBL2 | HPRD; |
interacts with |
RBX1 | BIOGRID; |
interacts with |
RBX1 | HPRD; |
interacts with |
RFC1 | BIOGRID; |
interacts with |
RFC1 | HPRD; |
interacts with |
SKP1 | BIOGRID; |
interacts with |
SP1 | HPRD; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
STAT3 | HPRD; |
interacts with |
TAF1 | BIOGRID; |
interacts with |
TAF1 | HPRD; |
interacts with |
THRA | BIOGRID; |
interacts with |
THRA | HPRD; |
interacts with |
THRB | BIOGRID; |
interacts with |
THRB | HPRD; |
interacts with |
TSC2 | BIOGRID; |
interacts with |
TSC2 | HPRD; |
interacts with |
TUBB | HPRD; |
interacts with |
WDR77 | BIOGRID; |
interacts with |
XPO1 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
AES | NCI_NATURE; |
metabolic catalysis |
AGAP2 | NCI_NATURE; |
metabolic catalysis |
ATF2 | NCI_NATURE; |
metabolic catalysis |
CHUK | NCI_NATURE; |
metabolic catalysis |
CREB1 | NCI_NATURE; |
metabolic catalysis |
CREBBP | NCI_NATURE; |
metabolic catalysis |
CTBP1 | NCI_NATURE; |
metabolic catalysis |
CTNNB1 | NCI_NATURE; |
metabolic catalysis |
ESR1 | NCI_NATURE; |
metabolic catalysis |
ETS1 | NCI_NATURE; |
metabolic catalysis |
FOS | NCI_NATURE; |
metabolic catalysis |
FOSL1 | NCI_NATURE; |
metabolic catalysis |
HBP1 | NCI_NATURE; |
metabolic catalysis |
HDAC1 | NCI_NATURE; |
metabolic catalysis |
HNF1A | NCI_NATURE; |
metabolic catalysis |
JUN | NCI_NATURE; |
metabolic catalysis |
KLF8 | NCI_NATURE; |
metabolic catalysis |
LEF1 | NCI_NATURE; |
metabolic catalysis |
NCOA3 | NCI_NATURE; |
metabolic catalysis |
NOTCH1 | NCI_NATURE; |
metabolic catalysis |
ONECUT1 | NCI_NATURE; |
metabolic catalysis |
PIK3CA | NCI_NATURE; |
metabolic catalysis |
PIK3R1 | NCI_NATURE; |
metabolic catalysis |
RAC1 | NCI_NATURE; |
metabolic catalysis |
RBPJ | NCI_NATURE; |
metabolic catalysis |
STAT3 | NCI_NATURE; |
metabolic catalysis |
TCF7L1 | NCI_NATURE; |
metabolic catalysis |
TCF7L2 | NCI_NATURE; |
metabolic catalysis |
TERT | NCI_NATURE; |
metabolic catalysis |
TLE1 | NCI_NATURE; |
metabolic catalysis |
ZBTB17 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
AR | NCI_NATURE; |
reacts with |
CCND1 | NCI_NATURE; |
reacts with |
CCND1 | REACTOME; |
reacts with |
CDK4 | REACTOME; |
reacts with |
CDK6 | NCI_NATURE; |
reacts with |
MYB | NCI_NATURE; |
state change |
MAPK12 | NCI_NATURE; |