| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4090 |
Name | SMAD5 |
Synonymous | SMAD family member 5;SMAD5;SMAD family member 5 |
Definition | MAD, mothers against decapentaplegic homolog 5|SMA- and MAD-related protein 5|SMAD, mothers against DPP homolog 5|mothers against decapentaplegic homolog 5|mothers against decapentaplegic, drosophila, homolog of, 5 |
Position | 5q31 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
SKI | NCI_NATURE; |
in same component |
SMAD4 | NCI_NATURE; |
in same component |
SMAD6 | NCI_NATURE; |
in same component |
SMURF1 | NCI_NATURE; |
interacts with |
ACVR1 | BIOGRID; |
interacts with |
ACVR1 | HPRD; |
interacts with |
ANKRD13A | MINT; |
interacts with |
BCAT1 | MINT; |
interacts with |
BMP6 | HPRD; |
interacts with |
CXXC5 | HPRD; |
interacts with |
CXXC5 | MINT; |
interacts with |
EP300 | BIOGRID; |
interacts with |
FLNA | HPRD; |
interacts with |
GDF6 | HPRD; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HMGA2 | BIOGRID; |
interacts with |
HOXA13 | HPRD; |
interacts with |
HOXD13 | HPRD; |
interacts with |
KAT2A | BIOGRID; |
interacts with |
MBD1 | HPRD; |
interacts with |
MEN1 | HPRD; |
interacts with |
MTMR10 | HPRD; |
interacts with |
MTMR10 | MINT; |
interacts with |
NEDD4 | MINT; |
interacts with |
PLEKHO1 | BIOGRID; |
interacts with |
PNKP | HPRD; |
interacts with |
PNKP | MINT; |
interacts with |
PPIL4 | HPRD; |
interacts with |
PPIL4 | MINT; |
interacts with |
PSMD11 | HPRD; |
interacts with |
PSMD11 | MINT; |
interacts with |
PTPN12 | HPRD; |
interacts with |
PTPN12 | MINT; |
interacts with |
RBM4 | HPRD; |
interacts with |
RBM4 | MINT; |
interacts with |
RUNX2 | BIOGRID; |
interacts with |
RUNX3 | BIOGRID; |
interacts with |
RYR2 | HPRD; |
interacts with |
RYR2 | MINT; |
interacts with |
SF3B1 | HPRD; |
interacts with |
SF3B1 | MINT; |
interacts with |
SFPQ | HPRD; |
interacts with |
SFPQ | MINT; |
interacts with |
SKI | BIOGRID; |
interacts with |
SMAD1 | HPRD; |
interacts with |
SMAD1 | MINT; |
interacts with |
SMAD4 | BIOGRID; |
interacts with |
SMAD4 | HPRD; |
interacts with |
SMAD4 | MINT; |
interacts with |
SMURF1 | BIOGRID; |
interacts with |
SMURF1 | MINT; |
interacts with |
SMURF2 | BIOGRID; |
interacts with |
SMURF2 | HPRD; |
interacts with |
SMURF2 | MINT; |
interacts with |
SNRNP70 | HPRD; |
interacts with |
SNRNP70 | MINT; |
interacts with |
SNRPA | HPRD; |
interacts with |
SNRPA | MINT; |
interacts with |
SOX5 | HPRD; |
interacts with |
SOX5 | MINT; |
interacts with |
SOX7 | HPRD; |
interacts with |
SOX7 | MINT; |
interacts with |
STUB1 | BIOGRID; |
interacts with |
SUV39H1 | BIOGRID; |
interacts with |
SUV39H1 | HPRD; |
interacts with |
SUV39H2 | BIOGRID; |
interacts with |
SUV39H2 | HPRD; |
interacts with |
TOB1 | BIOGRID; |
interacts with |
TOB1 | HPRD; |
interacts with |
U2AF2 | HPRD; |
interacts with |
U2AF2 | MINT; |
interacts with |
VPS24 | HPRD; |
interacts with |
VPS24 | MINT; |
interacts with |
WWP1 | BIOGRID; |
interacts with |
WWP1 | HPRD; |
interacts with |
WWP1 | MINT; |
interacts with |
ZEB2 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for SMAD5 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
SKI | NCI_NATURE; |
reacts with |
SMAD4 | NCI_NATURE; |
reacts with |
SMAD5 | NCI_NATURE; |
reacts with |
SMAD6 | NCI_NATURE; |
reacts with |
SMURF1 | NCI_NATURE; |
state change |
BMP6 | NCI_NATURE; |
state change |
BMPR2 | NCI_NATURE; |
state change |
PPM1A | NCI_NATURE; |