| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6196 |
Name | RPS6KA2 |
Synonym | HU-2|MAPKAPK1C|RSK|RSK3|S6K-alpha|S6K-alpha2|p90-RSK3|pp90RSK3;ribosomal protein S6 kinase, 90kDa, polypeptide 2;RPS6KA2;ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
Definition | 90 kDa ribosomal protein S6 kinase 2|MAP kinase-activated protein kinase 1c|MAPK-activated protein kinase 1c|MAPKAP kinase 1c|MAPKAPK-1c|RSK-3|S6K-alpha-2|p90-RSK 2|p90RSK2|ribosomal S6 kinase 3|ribosomal protein S6 kinase 90kDa polypeptide 2|ribosomal pr |
Position | 6q27 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
Pathway | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Ras Pathway;PANTHER;P04393 |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 6196 |
Links to all GeneRIF Items | 6196 |
Links to iHOP | 6196 |
Sequence Information | |
Nucleotide Sequence | >6196 : length: 6117 ATTCGAAGCTGCAAGTGCAGCGTTTACTCTGCCAAAGTCGCAGTACAGATTCCGAAGCCG CAGCGCCGTCCCCTCCTTTCCTCGCCCCAGCCCGAGCGGGAAGCGGCAGCAGCTCCCCAG AGCCCTGGCTTGGCAGGGAGGGGACGGCGCCCGAGCAGCCATATTGCAGCCCCCCGGGTC CCTCCTCCGGCCGGCGCAGGCCCCGCGCTCACGACCTCCTCTGGGAGCCGGATCTGTCCT CTCCATCGCCGCCACCCGCCGGCCTCTGCGTCCCTTGGCTTCCGACATCCCGTCTGGCCG TCCCCCTGTGCCGGTCCGAGCCTCTGTTTATTTCCTTTCCTACTATCAATACTCGACCAG CAGAAAAGGAAAGTTTAAAAATGCCAATCGCACAGTTGCTGGAACTATGGAAAAAGATCG AGGTGGAGCCTATGGAAATAGAGACCACAGAGGAGGATCTCAACCTGGATGTGGAGCCCA CCACAGAAGACACTGCAGAAGAAGGCAAAAGTGACTCAGCTGCCTGCAAGACAAAGGTAG CTGGATCCGTAGAGGGACTGAACAGACGGGCTGCGGGAATCAAAGTGGTGACTATAGCTG ACTGCCTTCATTCCAGAGAACCCGAGACACAGCATGAGGAAGAAGGCGTCGTGAAGGAGA TAGACATCAGCCATCATGTGAAGGAGGGCTTTGAGAAGGCAGATCCTTCCCAGTTTGAGC TGCTGAAGGTTTTAGGACAAGGATCCTATGGAAAGGTGTTCCTGGTGAGGAAGGTGAAGG GGTCCGACGCTGGGCAGCTCTACGCCATGAAGGTCCTTAAGAAAGCCACCCTAAAAGTTC GGGACCGAGTGAGATCGAAGATGGAGAGAGACATCTTGGCAGAAGTGAATCACCCCTTCA TTGTGAAGCTTCATTATGCCTTTCAGACGGAAGGAAAGCTCTACCTGATCCTGGACTTCC TGCGGGGAGGGGACCTCTTCACCCGGCTCTCCAAAGAGGTCATGTTCACGGAGGAGGATG TCAAGTTCTACCTGGCTGAGCTGGCCTTGGCTTTAGACCATCTCCACAGCCTGGGGATCA TCTACAGAGATCTGAAGCCTGAGAACATCCTCCTGGATGAAGAGGGGCACATTAAGATCA CAGATTTCGGCCTGAGTAAGGAGGCCATTGACCACGACAAGAGAGCGTACTCCTTCTGCG GGACGATCGAGTACATGGCGCCCGAGGTGGTGAACCGGCGAGGACACACGCAGAGTGCCG ACTGGTGGTCCTTCGGCGTGCTCATGTTTGAGATGCTCACGGGGTCCCTGCCGTTCCAGG GGAAGGACAGGAAGGAGACCATGGCTCTCATCCTCAAAGCCAAGCTGGGGATGCCGCAGT TCCTCAGTGGGGAGGCACAGAGTTTGCTGCGAGCTCTCTTCAAACGGAACCCCTGCAACC GGCTGGGTGCTGGCATTGACGGAGTGGAGGAAATTAAGCGCCATCCCTTCTTTGTGACCA TAGACTGGAACACGCTGTACCGGAAGGAGATCAAGCCACCGTTCAAACCAGCAGTGGGCA GGCCTGAGGACACCTTCCACTTTGACCCCGAGTTCACAGCGCGGACGCCCACAGACTCTC CTGGCGTCCCCCCGAGTGCAAACGCTCATCACCTGTTTAGAGGATTCAGCTTTGTGGCCT CAAGCCTGATCCAGGAGCCCTCACAGCAAGATCTGCACAAAGTCCCAGTTCACCCAATCG TGCAGCAGTTACACGGGAACAACATCCACTTCACCGATGGCTACGAGATCAAGGAGGACA TCGGGGTGGGCTCCTACTCAGTGTGCAAGCGATGTGTGCATAAAGCCACAGACACCGAGT ATGCCGTGAAGATCATTGATAAGAGCAAGAGAGACCCCTCGGAAGAGATTGAGATCCTCC TGCGGTACGGCCAGCACCCGAACATCATCACCCTCAAGGATGTCTATGATGATGGCAAGT TTGTGTACCTGGTAATGGAGCTGATGCGTGGTGGGGAGCTCCTGGACCGCATCCTCCGGC AGAGATACTTCTCGGAGCGCGAAGCCAGTGACGTCCTGTGCACCATCACCAAGACCATGG ACTACCTCCATTCCCAGGGGGTTGTTCATCGAGACCTGAAGCCGAGTAACATCCTGTACA GGGATGAGTCGGGGAGCCCAGAATCCATCCGAGTCTGCGACTTCGGCTTTGCCAAGCAGC TGCGCGCGGGGAACGGGCTGCTCATGACACCCTGCTACACGGCCAATTTCGTGGCCCCGG AGGTCCTGAAGCGTCAAGGCTATGATGCGGCGTGTGACATCTGGAGTTTGGGGATCCTGT TGTACACCATGCTGGCAGGATTTACCCCTTTTGCAAATGGGCCAGACGATACCCCTGAGG AGATTCTGGCGCGGATCGGCAGTGGGAAGTATGCCCTTTCTGGGGGAAACTGGGACTCGA TATCTGACGCAGCTAAAGACGTCGTGTCCAAGATGCTCCACGTGGACCCTCATCAGCGCC TGACGGCGATGCAAGTGCTCAAACACCCGTGGGTGGTCAACAGAGAGTACCTGTCCCCAA ACCAGCTCAGCCGACAGGACGTGCACCTGGTGAAGGGCGCGATGGCCGCCACCTACTTTG CTCTAAACAGAACACCTCAGGCCCCGCGGCTGGAGCCCGTGCTGTCATCCAACCTGGCTC AGCGCAGAGGCATGAAGAGACTCACGTCCACGCGGCTGTAGCGGGTGGGACCCTGGCCCC AGCGTCCCCTGCCAGCATCCTCGTGGGCTCACAGACCCCGGCCTCGGAGCCCGTCTGGCA CCCAGAGTGACCACAAGTCCAGCAGGGAGGCGGCGCCCGCCCTCGCCGTGTCCGTGTTTT CTTTTTCAGCCCCGGAGAGGGTCCTGACCTGGGGGCTTCTCCAAGCCTCACTGCGCCAGC CTCCCCGCCCGCTCTCTTTTCTCCCAAGCGAAACCAAATGCGCCCCTTCACCTCGCGTGC CCGTGCGAGGCCGGGGGCTTCTTTCAGAGCCCGCGGGTCCTCTCATACATGGCTTCTGTT TCTGCCGAGAGATCTGTTTTCCAATTATGAAGCCGGTCGGTTTGGTCAGACTCCCGACAC CCACGTCCCAGGTACCCGGTGGGAAAGTGGCAGTGCGAGGGCGCAGCCATTGGTGGTTGC AGGGCCCCAGAGGGCTGGGGTGACCTGGCATCCCGGGGCTCCCCACGGGCTGGATGACGG GGTTGGCACTGTGGCGTCCAGGAGGAGATGCCTGGTTCTGCCCAAAATAATCCAAAGAGC CGTTTCCTCCTCGCCCTTCAGTTTTTGCCTGAGGTGCTGGGTAGCCCATCCTTTCCTCTG TCCCAGATTCAAATGAGGAGTAAGAGCCCAGACGAGAGGAAGGCAGGCTGGATCTTTGCC TTGAGAGCTCCGTGTCACCAGGATGGAAGGGGGTGCCTCTCGGAGGAGCCTGTGTCCACC TCCAGTCTCGGCTTTCCCCGGGGGGCCAAGCGCACTGGGCTGCCGTCTGTCCCCAGCTCC CGTGGCCACACAGCTATCTGGAGGCTTTGCAGGGAGTCGTGGGTTCTCGCACCTGCTCAG CCCTGTGTCGGCTTCCTGTGTGCTCACCTAAAGCTGTGGTTTTGCTGTGTTCACTTCGAT TTTTCTGGTCTGTGGAGAAACTGTGAATTGGAGAAATGGAGCTCTGTGGCTTCCCACCCA AACCTTCTCAGTCCAGCTGGAGGCTGGAGGGAGACACAGGCCCCACCCAGCAGACTGAGG GGCAGAGGCACAGGTGGGAGGGCAGCGGAGATCAGCGTGGACAGGAGCGATGCACTTTGT AGATGCTGTGGCTTTGTGTTGCGTTTTGTGTCTCTGTTGCACAGATCTGTTTTTTCACAC TGATCCGTATTCCCCTGGGTGTGCACACAGGGCGGGTGTGGGGCATTTAGGCCATGCTGT GCTCTACTTCATTGAGTAAAATCGAGTGAGAGGTTCCGGGCAGCAGGATCGACGCCCAGT CCAGCCGGCAGAGGGAACACACGGGTCCTTCATTGTCCTGTAAGGGTGTTGAAGATGCTC CCTGGCGGCCCCCAAGCAGACTAGATGGGAGGAGGCGCCGCTCAGCCCCTCACCCTGCAT CACTGAAGAGCGGCGCCTCTGCAGCAAGCAGGGCTTCAGGAGGTGCCCGCTGGCCACAGC CAGGTTTTCCCTAAGAAGATGTTATTTTGTTGGGTTTTGTTCCCCCTCCATCTCGATTCT CGTACCCAACTAAAAAAAAAAAAATAAAGAAAAAATGTGCTGCGTTCTGAAAAATAACTC CTTAGCTTGGTCTGATTGTTTTCAGACCTTAAAATATAAACTTGTTTCACAAGCTTTAAT CCATGTGGATTTTTTTTTTCTTAGAGAACCACAAAACATAAAAGGAGCAAGTCGGACTGA ATACCTGTTTCCATAGTGCCCACAGGGTATTCCTCACATTTTCTCCATAGAAGATGCTTT TTCCCAAGGCTAGAACGACTTCCACCATGATGAATTTGCTTTTTAGGTCTTAATTATTTC ACTTCTTTTTAGAAACTTAGGAAGAAGTGGATAATCCTGAGGTCACACAATCTGTCCTCC CAGAAATGAACAAAAGTCATCACCTTTTCTGCTTGCTACACAGGCAACGATTCCCCCATC AGCTGCCCGGACCCTTTGGCCTGGCTTGGTGTGCAGGCCTGTCTGTTTGCTTAAAGTCAG TGGGTTCTGGTGCAGGGAGTGAGAAGTGGGGGAAGTGAAAGGGAAAGCATCCGTGAGAAA GCGGCCACGGTTTTCCCTCCTTGTGTGCCCATGGGGCACCAGCTCATGGTCTTTTTCAGT CATCCCAGTTTGTACAGACTTAGCTTCTGAACTCTAAGAATGCCAAAGGGACCGACGAGA CTCCCCATCACAGCGAGCTCTGTCCTTACATGTATTTGATGTGCATCAGCGGAGGAGAAC ACTGGCTTGGCCCTGCTCCGCTGAGTGTCTGTGAAATACCTCTACTTTCCCTCCCATATC CAGAACAAAATGATACTTGACATCCTTCCACAAAAGTCAGCCTAAAGAAGTTATGGTATC ATATGTTAAACTAAGCTTTCAAAAACCTTAGTGAAATAGCAAGTGACTGCTTTCAAGCAG CAGTCGACATGTAAATGAAGGTGTTCTTAGAATTCGCATTTTGCCAGCTCAGCGCACCTC CACAACGAATGAAATGCTCCGTATGATTTGCACAAATGACATAGACCTCCCCAAAAGTTA ACTGGCTCTCCTTCCTCACACAGTTCATCATAACCCAACCCCCCACCCCCGGGTCATGAA AATCACAGAACTTATAAACACATTGAACCCTAGATCTCAGGCTTCCTGACCTACCGCCAG TGGCCCCTTGCTGGCCACCCTATAGGGTCCTCCTTCCCTGGCAGCCCCCCATGTGGGAGA AATACCTGATTCTCCCAATCTGCAGTGGGAGAGCTTTGCTGAATTCCATCCCAAAGTCAA ACATGGGCAAGAGGTGAGGATTTCACTTTTACCCTCAAGTCCGATTTGTCTGTGATTTTA AACTAACTGTGTATGTATTGATGTTTGGAAGATTGTTTGAATTTTAAAGTGATAATAGTA CTTAATGTTATCCAGTATTGTTCATTAAATGGTGTTATCCTAAAGCTGCACTTGGGATTT TTACCTAACGCTTTACTGATTCTCTCAAGCACATGGCAAAGTTTGATTTGCACTCCGTTC ATTTCTGACACGTTTTGCTGCCTCCTACCTTTCTAAGCGTCATGCAAATTCGAGAATGGA GAAGGACGCTGCCGGTCCCTGAGCGGTGTGGAGAGGGCGGAAGGTGGACTCCAGCGCAGC TTGAGGGGCTGAGGACGGAGGCTGCAGCATCTGTGTCGTTCTACTGAGCACGCTTCTCTG CCTCGCTCCTGACTCAGCACTTTGTTCACTGGCTCAGCAGTTATGTTTACACATCATTTT TATGTTCCTGCTTTGTAATTCATGTTTGAGATGGGTGGCCACTGTACAGATATTTATTAC GCTTTCCAGACTTTCTGAATAGATTTTTTTGAATAAACATGGTTTTATGAAGTGTAA |
Protein Sequence | >6196 : length: 786 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVEPTTEDTAEEGKSDSAACKTKVAGSVEGL NRRAAGIKVVTIADCLHSREPETQHEEEGVVKEIDISHHVKEGFEKADPSQFELLKVLGQ GSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYA FQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKP ENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGV LMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLGAGID GVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSA NAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYS VCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFVYLVME LMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSP ESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAG FTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVL KHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKR LTSTRL |