| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5584 |
Name | PRKCI |
Synonym | DXS1179E|PKCI|nPKC-iota;protein kinase C, iota;PRKCI;protein kinase C, iota |
Definition | PRKC-lambda/iota|aPKC-lambda/iota|atypical protein kinase C-lambda/iota|protein kinase C iota type |
Position | 3q26.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | 5HT2 type receptor mediated signaling pathway;PANTHER;P04374 |
Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway;PANTHER;P00042 |
Pathway | Thyrotropin-releasing hormone receptor signaling pathway;PANTHER;P04394 |
Pathway | p75NTR recruits signalling complexes;PID Reactome;500614 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | TNF receptor signaling pathway;PID Curated;200086 |
Pathway | Endothelin signaling pathway;PANTHER;P00019 |
Pathway | Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Insulin Pathway;PID Curated;200012 |
Pathway | Histamine H1 receptor mediated signaling pathway;PANTHER;P04385 |
Pathway | VEGF signaling pathway;PANTHER;P00056 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | IL1-mediated signaling events;PID Curated;200075 |
Pathway | Alzheimer disease-amyloid secretase pathway;PANTHER;P00003 |
Pathway | Oxytocin receptor mediated signaling pathway;PANTHER;P04391 |
Pathway | Insulin-mediated glucose transport;PID Curated;200168 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
External Links | |
Links to Entrez Gene | 5584 |
Links to all GeneRIF Items | 5584 |
Links to iHOP | 5584 |
Sequence Information | |
Nucleotide Sequence | >5584 : length: 4884 AGGTGTCTTGGGCCCGGGCGGCTGTAGAGGCGGCGGCGCCTACGGGCAGTGGGAGGAGCC GCGCGGTTCCGGCTGCTCCGGCGAGGCGACCCTTGGGTCGGCGCTGCGGGCGAGGTGGGC AGGTAGGTGGGCGGACGGCCGCGGTTCTCCGGCAAGCGCAGGCGGCGGAGTCCCCCACGG CGCCCGAAGCGCCCCCCCGCACCCCCGGCCTCCAGCGTTGAGGCGGGGGAGTGAGGAGAT GCCGACCCAGAGGGACAGCAGCACCATGTCCCACACGGTCGCAGGCGGCGGCAGCGGGGA CCATTCCCACCAGGTCCGGGTGAAAGCCTACTACCGCGGGGATATCATGATAACACATTT TGAACCTTCCATCTCCTTTGAGGGCCTTTGCAATGAGGTTCGAGACATGTGTTCTTTTGA CAACGAACAGCTCTTCACCATGAAATGGATAGATGAGGAAGGAGACCCGTGTACAGTATC ATCTCAGTTGGAGTTAGAAGAAGCCTTTAGACTTTATGAGCTAAACAAGGATTCTGAACT CTTGATTCATGTGTTCCCTTGTGTACCAGAACGTCCTGGGATGCCTTGTCCAGGAGAAGA TAAATCCATCTACCGTAGAGGTGCACGCCGCTGGAGAAAGCTTTATTGTGCCAATGGCCA CACTTTCCAAGCCAAGCGTTTCAACAGGCGTGCTCACTGTGCCATCTGCACAGACCGAAT ATGGGGACTTGGACGCCAAGGATATAAGTGCATCAACTGCAAACTCTTGGTTCATAAGAA GTGCCATAAACTCGTCACAATTGAATGTGGGCGGCATTCTTTGCCACAGGAACCAGTGAT GCCCATGGATCAGTCATCCATGCATTCTGACCATGCACAGACAGTAATTCCATATAATCC TTCAAGTCATGAGAGTTTGGATCAAGTTGGTGAAGAAAAAGAGGCAATGAACACCAGGGA AAGTGGCAAAGCTTCATCCAGTCTAGGTCTTCAGGATTTTGATTTGCTCCGGGTAATAGG AAGAGGAAGTTATGCCAAAGTACTGTTGGTTCGATTAAAAAAAACAGATCGTATTTATGC AATGAAAGTTGTGAAAAAAGAGCTTGTTAATGATGATGAGGATATTGATTGGGTACAGAC AGAGAAGCATGTGTTTGAGCAGGCATCCAATCATCCTTTCCTTGTTGGGCTGCATTCTTG CTTTCAGACAGAAAGCAGATTGTTCTTTGTTATAGAGTATGTAAATGGAGGAGACCTAAT GTTTCATATGCAGCGACAAAGAAAACTTCCTGAAGAACATGCCAGATTTTACTCTGCAGA AATCAGTCTAGCATTAAATTATCTTCATGAGCGAGGGATAATTTATAGAGATTTGAAACT GGACAATGTATTACTGGACTCTGAAGGCCACATTAAACTCACTGACTACGGCATGTGTAA GGAAGGATTACGGCCAGGAGATACAACCAGCACTTTCTGTGGTACTCCTAATTACATTGC TCCTGAAATTTTAAGAGGAGAAGATTATGGTTTCAGTGTTGACTGGTGGGCTCTTGGAGT GCTCATGTTTGAGATGATGGCAGGAAGGTCTCCATTTGATATTGTTGGGAGCTCCGATAA CCCTGACCAGAACACAGAGGATTATCTCTTCCAAGTTATTTTGGAAAAACAAATTCGCAT ACCACGTTCTCTGTCTGTAAAAGCTGCAAGTGTTCTGAAGAGTTTTCTTAATAAGGACCC TAAGGAACGATTGGGTTGTCATCCTCAAACAGGATTTGCTGATATTCAGGGACACCCGTT CTTCCGAAATGTTGATTGGGATATGATGGAGCAAAAACAGGTGGTACCTCCCTTTAAACC AAATATTTCTGGGGAATTTGGTTTGGACAACTTTGATTCTCAGTTTACTAATGAACCTGT CCAGCTCACTCCAGATGACGATGACATTGTGAGGAAGATTGATCAGTCTGAATTTGAAGG TTTTGAGTATATCAATCCTCTTTTGATGTCTGCAGAAGAATGTGTCTGATCCTCATTTTT CAACCATGTATTCTACTCATGTTGCCATTTAATGCATGGATAAACTTGCTGCAAGCCTGG ATACAATTAACCATTTTATATTTGCCACCTACAAAAAAACACCCAATATCTTCTCTTGTA GACTATATGAATCAATTATTACATCTGTTTTACTATGAAAAAAAAATTAATACTACTAGC TTCCAGACAATCATGTCAAAATTTAGTTGAACTGGTTTTTCAGTTTTTAAAAGGCCTACA GATGAGTAATGAAGTTATCTTTTTTGTTTAAAAAAAAAAAAAACACTGCATTAAAAAAGT ATCTGTTGCATTAAGGCACATAGTGGGATTACATCATAAACCTCCCATAATTTTTGTCAT TCTGTGTTAAATCATTTCAGGGTTTAATTTTGAAATAAAAGATTAATATAAAATGCAACA ACTTTTTATATTACCTATTAGTTTTGGAGTTCTTTATGTTTAAAAATTCAGGTGTAAATT TTATTGCCTTGGATAAATAAATTATTGATCTTTTTTAAGGCAGCAGTTATTAAATTGGTA ATAGAAGATGCTGCTTGCTTAGAATTGGGAAATTCGGCTGGGTGCAGTGACTCAATGCCT GTGATCCCAGTACTTTGGGAGGTTGAGGCGGGCAGATCACTTGAGGTCAGGAGTTTGAGA TTGGCCTGGTCAACATGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCA TGGTGGCACATACCTGTAATCCCAGCTACTCGGGAGGCTGAAACAGGAGAATCGCTTGAA CCCAGGAGATGGAGTTGGCAGTGAGCCAAGATTAGCCTGGGCAACAGTGAGTGAGACTCG GTCTCAAACAAAAACCAAATTGGGAAATTCTTCTTGAGTTAAAAAAGACACTTTTTATTA TGAATCAGATTCCAAATCATTAACTATTTTTGCAAAACTGGCACAAGTGGTTTTTCTTTT TAAGTATATTAACAGGGTAGCTCCTGAGCCTTTCCCTTTATTGGAAACTTTAACTGCAGT GTTAATATATACACTGCAAAAGACCAAGGATGCAGTTGAATGGAAAATTACTCAGTGTAT AGAAAGGAAAAAAACCAGAAATTTAAAATAGATACAGAAAAGTACACTGGTAATATTTTT ATTTCCTATTGGAGAGTGAATCCCCACAGTTGCTTTTTGTGACTTGATTCAAATGAGGCA CTCATTATTGTTACCAAACTTGTAAAAGCATTCCATGTATTCAGTGGAGGCAGAATGTAT AATATTTTTTCCTTATAATTTAGCATACAGGAAAAGTATTTATTTTTTAAGTAGGGTATC TTAATTATGCTCATTTCTTCCCCTAAACCACATTATCTATATGATTGGACCCTTTAGTGA AATCAGAAAAATAAAGTAGGCATGAATAAATGTTCAGGACACACACATACACTCACACAC ATCACAGTATCAGCTCTTTCAGTGAGTTTTTATTAACTAGATAACACATGTAATACATAG TAGAATACATTTCAGAGGCAGAGTTCCTCGGATTATTTTTTATGGATATTAGTGTTCAGC AGCTTATTATTTAAAGGGGTGCCAAATATAGCATCCTTCTGTTGTTTATTTTAAATATAT TTTTAATGAAAAGGGACTTAAAAAGTAAACATGATTATCTAAATTACTTAAAATTTTTTA ATCTTAGTAAAAATTTTAGGAAAGTTATCTAGTTTAAATTTCAAATGTTTTAAAATTTGT AGGCATTTAATAAATTATCTTTTTTTGGAGGGGTGGATGCTGCATTTCATTGGAAATGTC ATTTTTCCAAAGTTTCTAGCTATATACTCTCTTTCCTTCAAATAACATAAGTCTGAAAGC AATGAAAACGTCAAAGGAAAATGTTTATATACATCCACATGTTTATTTAATATGTTTCTC TTAACACCTGAAACTTGTTTTAAAACAAAAAGCAGTATTCACTTCAAATCATAAACTTAG AATTCTGTATCTCATGTCAGAAATATGTTTATGGCCTTGCTTTTAAGTGGTGCTGTTTCC CATAGGGCATTAGTTCTCAGATTTTGGAATGTGAAATAATCACCTAGGAAGTTGGTTTAA AATGCACACTAGTGAGCCCACCTTAGACTTCTTTTGGGGCCTTCGACCTCACTTTGAGAA ATACCTTCTTCAGGTTATTCTTTATGTTTGTCCTGTGGTTAAATATTAGAGTATTCATGA TAAAACATTTTGAGAAGGGGTAAGCAGTGAGTTATTACCCACAATTTAAAGCAAATTTTG AATGAATCTTTAAGTTAGGTATCTACCTTCCCACCAGCCCCCCAAAAAACCTCTCAGTAG TTTCTTTCAGTGTACAAAATGATGAGCATTTTTCTATGATGAGGTTTTAACCATTATTCA GGGTGGTCTTTTGTTTTTAAATCTTTTTTTAACTAATAAGATTTACGGTGTGTATTTTAT ACAGAAATGCATTATAAATGTTTTTAATTGTGTTCTGTTTTTTGCAGTCTTTAAGTGCCA TGCCAATTGTTCTTATATTCTATAGAAGTTCGCTCAAAATACTCAACAGGGGAATAGGCA GCGGACAGTCAGAATGGTTGGAATTTTGGCTTTCTAAGAAAAACTTTATTTTGCATAAGC ATGTGGTCAGATCATTTTGTGCATATGCAGCCTGGATTGGATGTTAAGTAAATGCTTGTT CAGTGCCGGTACATTTACTTAAATCTGTTTTTATTTTTGTCATGTAGAATACTACTGTGG TCATCATAATGTAATCTATTTCTGTACCTTTTTTTTTTTTTTTTACTTTGAAGTCTTTAA ATAAAATGTATAATACCCATTGAG |
Protein Sequence | >5584 : length: 596 MPTQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSF DNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGE DKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHK KCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTR ESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQ TEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSA EISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYI APEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIR IPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFK PNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV |