| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2308 |
Name | FOXO1 |
Synonym | FKH1|FKHR|FOXO1A;forkhead box O1;FOXO1;forkhead box O1 |
Definition | forkhead box protein O1|forkhead box protein O1A|forkhead, Drosophila, homolog of, in rhabdomyosarcoma |
Position | 13q14.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Class I PI3K signaling events mediated by Akt;PID Curated;200169 |
Pathway | Signaling events mediated by HDAC Class III;PID Curated;200020 |
Pathway | AKT-mediated inactivation of FOXO1A;PID Reactome;500523 |
Pathway | Regulation of Androgen receptor activity;PID Curated;200102 |
Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Regulation of beta-cell development;Reactome;REACT:13698 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Regulation of gene expression in beta cells;PID Reactome;500522 |
Disease | Cancers;KEGG DISEASE |
Disease | Rhabdomyosarcoma, alveolar;OMIM |
Disease | Prostate cancer;FunDO |
Disease | Muscular atrophy;FunDO |
Disease | Cancers of soft tissues and bone;KEGG DISEASE |
Disease | Leukemia;FunDO |
Disease | Congenital abnormality;FunDO |
Disease | Alveolar rhabdomyosarcoma;KEGG DISEASE;H00037 |
Disease | Central corneal thickness;NHGRI |
External Links | |
Links to Entrez Gene | 2308 |
Links to all GeneRIF Items | 2308 |
Links to iHOP | 2308 |
Sequence Information | |
Nucleotide Sequence | >2308 : length: 5738 GCAGCCGCCACATTCAACAGGCAGCAGCGCAGCGGGCGCGCCGCTGGGGAGAGCAAGCGG CCCGCGGCGTCCGTCCGTCCTTCCGTCCGCGGCCCTGTCAGCTGGAGCGCGGCGCAGGCT CTGCCCCGGCCCGGCGGCTCTGGCCGGCCGTCCAGTCCGTGCGGCGGACCCCGAGGAGCC TCGATGTGGATGGCCCCGCGAAGTTAAGTTCTGGGCTCGCGCTTCCACTCCGCCGCGCCT TCCTCCCAGTTTCCGTCCGCTCGCCGCACCGGCTTCGTTCCCCCAAATCTCGGACCGTCC CTTCGCGCCCCCTCCCCGTCCGCCCCCAGTGCTGCGTTCTCCCCCTCTTGGCTCTCCTGC GGCTGGGGGAGGGGCGGGGGTCACCATGGCCGAGGCGCCTCAGGTGGTGGAGATCGACCC GGACTTCGAGCCGCTGCCCCGGCCGCGCTCGTGCACCTGGCCGCTGCCCAGGCCGGAGTT TAGCCAGTCCAACTCGGCCACCTCCAGCCCGGCGCCGTCGGGCAGCGCGGCTGCCAACCC CGACGCCGCGGCGGGCCTGCCCTCGGCCTCGGCTGCCGCTGTCAGCGCCGACTTCATGAG CAACCTGAGCTTGCTGGAGGAGAGCGAGGACTTCCCGCAGGCGCCCGGCTCCGTGGCGGC GGCGGTGGCGGCGGCGGCCGCCGCGGCCGCCACCGGGGGGCTGTGCGGGGACTTCCAGGG CCCGGAGGCGGGCTGCCTGCACCCAGCGCCACCGCAGCCCCCGCCGCCCGGGCCGCTGTC GCAGCACCCGCCGGTGCCCCCCGCCGCCGCTGGGCCGCTCGCGGGGCAGCCGCGCAAGAG CAGCTCGTCCCGCCGCAACGCGTGGGGCAACCTGTCCTACGCCGACCTCATCACCAAGGC CATCGAGAGCTCGGCGGAGAAGCGGCTCACGCTGTCGCAGATCTACGAGTGGATGGTCAA GAGCGTGCCCTACTTCAAGGATAAGGGTGACAGCAACAGCTCGGCGGGCTGGAAGAATTC AATTCGTCATAATCTGTCCCTACACAGCAAGTTCATTCGTGTGCAGAATGAAGGAACTGG AAAAAGTTCTTGGTGGATGCTCAATCCAGAGGGTGGCAAGAGCGGGAAATCTCCTAGGAG AAGAGCTGCATCCATGGACAACAACAGTAAATTTGCTAAGAGCCGAAGCCGAGCTGCCAA GAAGAAAGCATCTCTCCAGTCTGGCCAGGAGGGTGCTGGGGACAGCCCTGGATCACAGTT TTCCAAATGGCCTGCAAGCCCTGGCTCTCACAGCAATGATGACTTTGATAACTGGAGTAC ATTTCGCCCTCGAACTAGCTCAAATGCTAGTACTATTAGTGGGAGACTCTCACCCATTAT GACCGAACAGGATGATCTTGGAGAAGGGGATGTGCATTCTATGGTGTACCCGCCATCTGC CGCAAAGATGGCCTCTACTTTACCCAGTCTGTCTGAGATAAGCAATCCCGAAAACATGGA AAATCTTTTGGATAATCTCAACCTTCTCTCATCACCAACATCATTAACTGTTTCGACCCA GTCCTCACCTGGCACCATGATGCAGCAGACGCCGTGCTACTCGTTTGCGCCACCAAACAC CAGTTTGAATTCACCCAGCCCAAACTACCAAAAATATACATATGGCCAATCCAGCATGAG CCCTTTGCCCCAGATGCCTATACAAACACTTCAGGACAATAAGTCGAGTTATGGAGGTAT GAGTCAGTATAACTGTGCGCCTGGACTCTTGAAGGAGTTGCTGACTTCTGACTCTCCTCC CCATAATGACATTATGACACCAGTTGATCCTGGGGTAGCCCAGCCCAACAGCCGGGTTCT GGGCCAGAACGTCATGATGGGCCCTAATTCGGTCATGTCAACCTATGGCAGCCAGGCATC TCATAACAAAATGATGAATCCCAGCTCCCATACCCACCCTGGACATGCTCAGCAGACATC TGCAGTTAACGGGCGTCCCCTGCCCCACACGGTAAGCACCATGCCCCACACCTCGGGTAT GAACCGCCTGACCCAAGTGAAGACACCTGTACAAGTGCCTCTGCCCCACCCCATGCAGAT GAGTGCCCTGGGGGGCTACTCCTCCGTGAGCAGCTGCAATGGCTATGGCAGAATGGGCCT TCTCCACCAGGAGAAGCTCCCAAGTGACTTGGATGGCATGTTCATTGAGCGCTTAGACTG TGACATGGAATCCATCATTCGGAATGACCTCATGGATGGAGATACATTGGATTTTAACTT TGACAATGTGTTGCCCAACCAAAGCTTCCCACACAGTGTCAAGACAACGACACATAGCTG GGTGTCAGGCTGAGGGTTAGTGAGCAGGTTACACTTAAAAGTACTTCAGATTGTCTGACA GCAGGAACTGAGAGAAGCAGTCCAAAGATGTCTTTCACCAACTCCCTTTTAGTTTTCTTG GTTAAAAAAAAAAACAAAAAAAAAAACCCTCCTTTTTTCCTTTCGTCAGACTTGGCAGCA AAGACATTTTTCCTGTACAGGATGTTTGCCCAATGTGTGCAGGTTATGTGCTGCTGTAGA TAAGGACTGTGCCATTGGAAATTTCATTACAATGAAGTGCCAAACTCACTACACCATATA ATTGCAGAAAAGATTTTCAGATCCTGGTGTGCTTTCAAGTTTTGTATATAAGCAGTAGAT ACAGATTGTATTTGTGTGTGTTTTTGGTTTTTCTAAATATCCAATTGGTCCAAGGAAAGT TTATACTCTTTTTGTAATACTGTGATGGGCCTCATGTCTTGATAAGTTAAACTTTTGTTT GTACTACCTGTTTTCTGCGGAACTGACGGATCACAAAGAACTGAATCTCCATTCTGCATC TCCATTGAACAGCCTTGGACCTGTTCACGTTGCCACAGAATTCACATGAGAACCAAGTAG CCTGTTATCAATCTGCTAAATTAATGGACTTGTTAAACTTTTGGAAAAAAAAAGATTAAA TGCCAGCTTTGTACAGGTCTTTTCTATTTTTTTTTGTTTATTTTGTTATTTGCAAATTTG TACAAACATTTAAATGGTTCTAATTTCCAGATAAATGATTTTTGATGTTATTGTTGGGAC TTAAGAACATTTTTGGAATAGATATTGAACTGTAATAATGTTTTCTTAAAACTAGAGTCT ACTTTGTTACATAGTCAGCTTGTAAATTTTGTGGAACCACAGGTATTTGGGGCAGCATTC ATAATTTTCATTTTGTATTCTAACTGGATTAGTACTAATTTTATACATGCTTAACTGGTT TGTACACTTTGGGATGCTACTTAGTGATGTTTCTGACTAATCTTAAATCATTGTAATTAG TACTTGCATATTCAACGTTTCAGGCCCTGGTTGGGCAGGAAAGTGATGTATAGTTATGGA CACTTTGCGTTTCTTATTTAGGATAACTTAATATGTTTTTATGTATGTATTTTAAAGAAA TTTCATCTGCTTCTACTGAACTATGCGTACTGCATAGCATCAAGTCTTCTCTAGAGACCT CTGTAGTCCTGGGAGGCCTCATAATGTTTGTAGATCAGAAAAGGGAGATCTGCATCTAAA GCAATGGTCCTTTGTCAAACGAGGGATTTTGATCCACTTCACCATTTTGAGTTGAGCTTT AGCAAAAGTTTCCCCTCATAATTCTTTGCTCTTGTTTCAGTCCAGGTGGAGGTTGGTTTT GTAGTTCTGCCTTGAGGAATTATGTCAACACTCATACTTCATCTCATTCTCCCTTCTGCC CTGCAGATTAGATTACTTAGCACACTGTGGAAGTTTAAGTGGAAGGAGGGAATTTAAAAA TGGGACTTGAGTGGTTTGTAGAATTTGTGTTCATAAGTTCAGATGGGTAGCAAATGGAAT AGAACTTACTTAAAAATTGGGGAGATTTATTTGAAAACCAGCTGTAAGTTGTGCATTGAG ATTATGTTAAAAGCCTTGGCTTAAGAATTTGAAAATTTCTTTAGCCTGTAGCAACCTAAA CTGTAATTCCTATCATTATGTTTTATTACTTTCCAATTACCTGTAACTGACAGACCAAAT TAATTGGCTTTGTGTCCTATTTAGTCCATCAGTATTTTCAAGTCATGTGGAAAGCCCAAA GTCATCACAATGAAGAGAACAGGTGCACAGCACTGTTCCTCTTGTGTTCTTGAGAAGGAT CTAATTTTTCTGTATATAGCCCACATCACACTTGCTTTGTCTTGTATGTTAATTGCATCT TCATTGGCTTGGTATTTCCTAAATGTTTAACAAGAACACAAGTGTTCCTGATAAGATTTC CTACAGTAAGCCAGCTCTATTGTAAGCTTCCCACTGTGATGATCATTTTTTTGAAGATTC ATTGAACAGCCACCACTCTATCATCCTCATTTTGGGGCAGTCCAAGACATAGCTGGTTTT AGAAACCCAAGTTCCTCTAAGCACAGCCTCCCGGGTATGTAACTGAACTTGGTGCCAAAG TACTTGTGTACTAATTTCTATTACTACGTACTGTCACTTTCCTCCCGTGCCATTACTGCA TCATAATACAAGGAACCTCAGAGCCCCCATTTGTTCATTAAAGAGGCAACTACAGCCAAA ATCACTGTTAAAATCTTACTACTTCATGGAGTAGCTCTTAGGAAAATATATCTTCCTCCT GAGTCTGGGTAATTATACCTCTCCCAAGCCCCCATTGTGTGTTGAAATCCTGTCATGAAT CCTTGGTAGCTCTCTGAGAACAGTGAAGTCCAGGGAAAGGCATCTGGTCTGTCTGGAAAG CAAACATTATGTGGCCTCTGGTAGTTTTTTTCCTGTAAGAATACTGACTTTCTGGAGTAA TGAGTATATATCAGTTATTGTACATGATTGCTTTGTGAAATGTGCAAATGATATCACCTA TGCAGCCTTGTTTGATTTATTTTCTCTGGTTTGTACTGTTATTAAAAGCATATTGTATTA TAGAGCTATTCAGATATTTTAAATATAAAGATGTATTGTTTCCGTAATATAGACGTATGG AATATATTTAGGTAATAGATGTATTACTTGGAAAGTTCTGCTTTGACAAACTGACAAAGT CTAAATGAGCACATGTATCCCAGTGAGCAGTAAATCAATGGAACATCCCAAGAAGAGGAT AAGGATGCTTAAAATGGAAATCATTCTCCAACGATATACAAATTGGACTTGTTCAACTGC TGGATATATGCTACCAATAACCCCAGCCCCAACTTAAAATTCTTACATTCAAGCTCCTAA GAGTTCTTAATTTATAACTAATTTTAAAAGAGAAGTTTCTTTTCTGGTTTTAGTTTGGGA ATAATCATTCATTAAAAAAAATGTATTGTGGTTTATGCGAACAGACCAACCTGGCATTAC AGTTGGCCTCTCCTTGAGGTGGGCACAGCCTGGCAGTGTGGCCAGGGGTGGCCATGTAAG TCCCATCAGGACGTAGTCATGCCTCCTGCATTTCGCTACCCGAGTTTAGTAACAGTGCAG ATTCCACGTTCTTGTTCCGATACTCTGAGAAGTGCCTGATGTTGATGTACTTACAGACAC AAGAACAATCTTTGCTATAATTGTATAAAGCCATAAATGTACATAAATTATGTTTAAATG GCTTGGTGTCTTTCTTTTCTAATTATGCAGAATAAGCTCTTTATTAGGAATTTTTTGTGA AGCTATTAAATACTTGAGTTAAGTCTTGTCAGCCACAA |
Protein Sequence | >2308 : length: 655 MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPS ASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHP APPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKR LTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLN PEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPG SHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLP SLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPN YQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPHNDIMTPV DPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLP HTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPS DLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG |