| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2100 |
Name | ESR2 |
Synonym | ER-BETA|ESR-BETA|ESRB|ESTRB|Erb|NR3A2;estrogen receptor 2 (ER beta);ESR2;estrogen receptor 2 (ER beta) |
Definition | estrogen receptor beta|estrogen receptor beta 4|nuclear receptor subfamily 3 group A member 2 |
Position | 14q23.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | Plasma membrane estrogen receptor signaling;PID Curated;200029 |
Disease | bulimia;GAD |
Disease | endometriosis;GAD |
Disease | Myasthenia Gravis;FunDO |
Disease | homocysteine nitric oxide;GAD |
Disease | Cancer;FunDO |
Disease | Cholelithiasis;FunDO |
Disease | Parkinson disease;FunDO |
Disease | Glaucoma;FunDO |
Disease | Infertility, Male;GAD |
Disease | bone density fracture risk osteoporosis, postmenopausal;GAD |
Disease | Parkinson's disease;GAD |
Disease | prostate cancer;GAD |
Disease | Dental plaque;FunDO |
Disease | Ptosis;FunDO |
Disease | Schizophrenia;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | bone density fractures, vertebral;GAD |
Disease | Bone Mineral Density;GAD |
Disease | METABOLIC;GAD |
Disease | bone density;GAD |
Disease | PSYCH;GAD |
Disease | Ovarian disease;FunDO |
Disease | REPRODUCTION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Late pregnancy;FunDO |
Disease | Testicular dysfunction;FunDO |
Disease | blood pressure;GAD |
Disease | hypospadias;GAD |
Disease | Endometriosis;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | Hypertension;FunDO |
Disease | blood pressure, arterial;GAD |
Disease | bone mass;GAD |
Disease | hormone disturbance;GAD |
Disease | Osteoporosis;FunDO |
Disease | breast cancer;GAD |
Disease | CANCER;GAD |
Disease | menstrual disorders;GAD |
Disease | cholesterol cholesterol, HDL cholesterol, LDL fatty acid glucose insulin lipoprotein triacylglycerols;GAD |
Disease | Temporal arteritis;FunDO |
Disease | dementia, vascular;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 2100 |
Links to all GeneRIF Items | 2100 |
Links to iHOP | 2100 |
Sequence Information | |
Nucleotide Sequence | >2100 : length: 4595 TTCTCAAAGTTTGCACAAGCGGATATTTTAGAGGTACAGTGTAATATAAGAGCTTCTGAA AATGTCCACTTAAGTTGTTTTATACCTGAGCAAGTGAAATTAAGAAGGGAATTGAAGCAA ATATTCCTGACATCCAAGTGGAGATATGGCATTTAAATTCATGAGATTGGATGAGATCCC ACCAAAGGAACAGGTTTAGGTGGAGACAACCAAATACCGATGCCTAGGACACTGCAGTGT TTAGAATTCAAGGAGATGAGAAGGAAACAGGAGGGAAGATTGAAAAGAAGAGTCCAGTGT GTTATGAGGAAAACCCCAAGAGCATGCTGCCTTACAAGACAGGTGAAAAATGTGTTCTGT GAAAGAAAGAGTAATTAACTGTTAAATGTTACAGACTGATCAAATAAAATGAAGACTGAG AATGGCCTGTTTGTAAGGGACTCTAGAAATGCCAGATAATTCCACTTTTGTGGTGACAGA AGAATCTGGCAATAATAGCTACCGTTTACTGAACAACAACTGCACATTAAGCACTGTGTC ATATGCTTTAGAGGGAGACATCAACCTGTTGTGGAAAAGAATGATCACTTAAAGTCTTTA GAAATTCTGAACCAACTCTCTAGCAGGTGATCCTTGTTAGAATTTGAGCCCTTAACGCTA TCCAGGACTGGAGGTTGAAGGGACGATAGAGGGAGCAGGAGGAGAATGCACATGGATTAA GGAGCGAGAACACAGAAATCCTGGGCTCTCTTCTCCCAGCCACAAGGTTAGGTTGAAAAA CAGAGCAGATGGAGGTAGTTTGTAGCCTACAGGTGCCCTGAATGAAGCTTCCACAGTGCT AAAGTGGAAGAACGAGGGACTCCAAGGGAAGGATTCAAGGCTGGGCCCATGCACCTGTGT AATTCAGAAGAGACCCCAGAGGAGATCAGCGCCCTCTAATTAGCCCTGCCATTATACTTG CCCACGAATCTTTGAGAACATTATAATGACCTTTGTGCCTCTTCTTGCAAGGTGTTTTCT CAGCTGTTATCTCAAGACATGGATATAAAAAACTCACCATCTAGCCTTAATTCTCCTTCC TCCTACAACTGCAGTCAATCCATCTTACCCCTGGAGCACGGCTCCATATACATACCTTCC TCCTATGTAGACAGCCACCATGAATATCCAGCCATGACATTCTATAGCCCTGCTGTGATG AATTACAGCATTCCCAGCAATGTCACTAACTTGGAAGGTGGGCCTGGTCGGCAGACCACA AGCCCAAATGTGTTGTGGCCAACACCTGGGCACCTTTCTCCTTTAGTGGTCCATCGCCAG TTATCACATCTGTATGCGGAACCTCAAAAGAGTCCCTGGTGTGAAGCAAGATCGCTAGAA CACACCTTACCTGTAAACAGAGAGACACTGAAAAGGAAGGTTAGTGGGAACCGTTGCGCC AGCCCTGTTACTGGTCCAGGTTCAAAGAGGGATGCTCACTTCTGCGCTGTCTGCAGCGAT TACGCATCGGGATATCACTATGGAGTCTGGTCGTGTGAAGGATGTAAGGCCTTTTTTAAA AGAAGCATTCAAGGACATAATGATTATATTTGTCCAGCTACAAATCAGTGTACAATCGAT AAAAACCGGCGCAAGAGCTGCCAGGCCTGCCGACTTCGGAAGTGTTACGAAGTGGGAATG GTGAAGTGTGGCTCCCGGAGAGAGAGATGTGGGTACCGCCTTGTGCGGAGACAGAGAAGT GCCGACGAGCAGCTGCACTGTGCCGGCAAGGCCAAGAGAAGTGGCGGCCACGCGCCCCGA GTGCGGGAGCTGCTGCTGGACGCCCTGAGCCCCGAGCAGCTAGTGCTCACCCTCCTGGAG GCTGAGCCGCCCCATGTGCTGATCAGCCGCCCCAGTGCGCCCTTCACCGAGGCCTCCATG ATGATGTCCCTGACCAAGTTGGCCGACAAGGAGTTGGTACACATGATCAGCTGGGCCAAG AAGATTCCCGGCTTTGTGGAGCTCAGCCTGTTCGACCAAGTGCGGCTCTTGGAGAGCTGT TGGATGGAGGTGTTAATGATGGGGCTGATGTGGCGCTCAATTGACCACCCCGGCAAGCTC ATCTTTGCTCCAGATCTTGTTCTGGACAGGGATGAGGGGAAATGCGTAGAAGGAATTCTG GAAATCTTTGACATGCTCCTGGCAACTACTTCAAGGTTTCGAGAGTTAAAACTCCAACAC AAAGAATATCTCTGTGTCAAGGCCATGATCCTGCTCAATTCCAGTATGTACCCTCTGGTC ACAGCGACCCAGGATGCTGACAGCAGCCGGAAGCTGGCTCACTTGCTGAACGCCGTGACC GATGCTTTGGTTTGGGTGATTGCCAAGAGCGGCATCTCCTCCCAGCAGCAATCCATGCGC CTGGCTAACCTCCTGATGCTCCTGTCCCACGTCAGGCATGCGAGTAACAAGGGCATGGAA CATCTGCTCAACATGAAGTGCAAAAATGTGGTCCCAGTGTATGACCTGCTGCTGGAGATG CTGAATGCCCACGTGCTTCGCGGGTGCAAGTCCTCCATCACGGGGTCCGAGTGCAGCCCG GCAGAGGACAGTAAAAGCAAAGAGGGCTCCCAGAACCCACAGTCTCAGTGACGCCTGGCC CTGAGGTGAACTGGCCCACAGAGGTCACAGGCTGAAGCGTGAACTCCAGTGTGTCAGGAG CCTGGGCTTCATCTTTCTGCTGTGTGGTCCCTCATTTGGTGATGGCAGGCTTGGTCATGT ACCATCCTTCCCTCCACCTTCCCAACTCTCAGGAGTCGGTGTGAGGAAGCCATAGTTTCC CTTGTTAGCAGAGGGCACATTTGAATGCAGCGTTTCCACACTCAATGGCCTCATAGGATC TCAGTGTGGTCTTTCTTACTTTCCTTCTTCCTTCCTCCCCTTTGTGAAACATCTTAAAGG TTTTGGAATGAATGGTGGAAATCTGACTTGGAAGGGCTGCGAATCAGAAAGGGGAGAGGA AGTGACACGCTTACAGAAGTGGGCTAACCCTTCTTGTGTGGCACACACTACCCTTCCCTC TGAGAGTTGACCTTTGCTGTTTTCCGGACCACTCCATTGTAAGATTGAAAACCCCTGTGG CAATTGCGTACTTACCTCCCAGGCCTGTGGGGACTGATCATATCATATGATGCTTATTCT GTCAAAGGCCAGAGGGACTGTGGTTAAGCTGGGATGTGAGTCATGTTCTCTCCCTGACCT TGCTGCCAGCTGCACACAGATTTGTCCCTCTCGATTTGTATTCACAGAGCCTGCCAATAA TTTGGGGTATGTGTGTATGAGCGTGTGATCATTTTCATGCAGGACTGTGGGAGATACAAA TCTCGCTGCTTCTGGAGCTGCTCTTCCTTAAACCTGTTGTCCCATGGGGCCAGCGTGGGT GCTGGAGAAAGGCCGTGTTTGCAGGAATGGGGTTCTCTCCTGTGGGTGTGGGTGACAGCC ACAGTGTTTCCCTGGGGCAATGTGGATGCAGTTTCCATCTTGTACAACCTCATAAGTAGC AGCCACAATTGCCCCATCAGTCACCACAAGTAGTCAGGGATACTTTGGGCTGTGGATGTG TGCAGTGTGCTGTTTTATGGATGGATGAGTAGCTATGCACCCCAGTGTGTCAGCTCTGGG GCCACACTGTATAGCCTTGATGAGTACGCCCCTTGAACAAGACCCAGTTTGTGAACTCTC CTTAAAGAGAAATATTTAGGGATAATTATTTATAGCAAGAAAGAATTCTTTTACACTTGA GAGCTCTTTTAAAAATATTTTCTTATTGGAAAATTTATATGGTGGGCAGGGTGAAAAAGA AACAGTAAAAATATTAGTTCTTATTCCAAGTGGAACATAAATAGGACATGAAGAAGGGCA CCTCTGAAATGACAACTTTAACTCACCTTTTAAAAGATGTGAAATTTCCAGTTTTGGATA CACGGTGAATATGTAAAATGAGTAACAGCATACTATGGAAGCCAGCAATTAAATAATCAT GTTTCATTATTGCAGTAACGTTTTAAACAATTACCTTGTGATATGATATTAAATATATTT TCTTTTTGAAAATATGTTCACTTTGGGTAGCACATCCTGTATTTACTAAGTCATTAGGAA GACTGCATTCAGTGTTACCAAGACTGGTTTTTGCTAGTAAGACCTCGAATAATCCATAAT TTTGATATTGGTGCAATTTTACTATAAGTTGAGCTTAGCTGTTTCAGAAATGCTTGGACA AGTACCTAGAGAACACACTGATGTCTGTGTTCTGAGGCAGTCTGAAGTTATTCTTAGAGA CTCAGTTACAGCTTTAGTAAGATTTAGTACAGGCAGGATAAGCTTGGTTTCATAGGAACC AGGGAACCAGTGTTAGTGTCAGCTTCTTTCCTCCTGGTCAGCCTAGAATCCCCCACTCCC AATAGAGGGGTTTGGAAGCTGGAGAGTAGGAAGTAAGAGGCAAAGAAGGCAGCCTTCAGC AACTCATTATCTGCCAGTGAAATTCTATTAAATGTATTTTTAAAAGAGATTACCAGGTAA CAAAAACATAAAAAACCAAAACAAGGCCAGATGTG |
Protein Sequence | >2100 : length: 540 MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARRQSVGIFPKWE LININRASLIYKGISEKPEDHPYPKEESQMHPQEQHTNKRNSNWTTGTPRASLQHIVLRK |