| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9971 |
Name | NR1H4 |
Synonymous | nuclear receptor subfamily 1, group H, member 4;NR1H4;nuclear receptor subfamily 1, group H, member 4 |
Definition | RXR-interacting protein 14|bile acid receptor|farnesoid X nuclear receptor|farnesoid X-activated receptor|farnesol receptor HRR-1|retinoid X receptor-interacting protein 14 |
Position | 12q23.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | FXR-isoform4(h) + RXR-alpha(h) <==> FXR-isoform4(h):RXR-alpha(h) (binding). | SRC-1(h) + FXR-isoform4(h) <==> FXR-isoform4(h):SRC-1(h) (binding; assembly) | FXR-isoform4(h) + TIF2(h) <==> FXR-isoform4(h):TIF2(h) (binding) | NR1H4(h) --> FXR-isoform4(h) (expression). | NR1H4(h) --> FXR-isoform2(h) (expression). | NR1H4(h) --> FXR-isoform1(h) (expression). | FXR-isoform3(h) --/ apoAI(h) (DNA binding; transrepression). | FXR-isoform3(h) + RXR-alpha(m) <==> FXR-isoform3(h):RXR-alpha(m) (binding). | FXR-isoform3(h) + RXR-alpha(h) <==> FXR-isoform3(h):RXR-alpha(h) (binding). | FXR-isoform3(h) + FXR-isoform3(h) <==> FXR-isoform3(h):FXR-isoform3(h) (binding). | FXR-isoform3(h) --> PPARA(h) (DNA binding). | FXR-isoform3(h) --> SLCO1B3(h) (DNA binding). | FXR-isoform3(h) --> BAAT(h) (DNA binding; transactivation). | FXR-isoform3(h) --> HHEX(h) (DNA binding; transactivation). | NR1H4(h) --> FXR-isoform3(h) (expression). | SMRT(h) + FXR(h) <==> SMRT(h):FXR(h) (binding) | 3alpha,7alpha,12alpha,26-tetrahydroxy-5beta-cholestane + FXR(h) <==> 3alpha,7alpha,12alpha,26-tetrahydroxy-5beta-cholestane:FXR(h) (binding) | cholestane-3,7,26-triol + FXR(h) <==> cholestane-3,7,26-triol:FXR(h) (binding) | DHCA + FXR(h) <==> DHCA:FXR(h) (binding) | chenodeoxycholic acid + FXR(h) <==> chenodeoxycholic acid:FXR(h) (binding) | cholestane-3,7,12,25-tetrol + FXR(h) <==> cholestane-3,7,12,25-tetrol:FXR(h) (binding) | FXR(h) + SRC-1(h) <==> FXR(h):SRC-1(h) (binding) | deoxycholate + FXR(h) <==> deoxycholate:FXR(h) (binding) | cholate + FXR(h) <==> cholate:FXR(h) (binding) | ursodeoxycholate + FXR(h) <==> ursodeoxycholate:FXR(h) (binding) | lithocholate + FXR(h) <==> lithocholate:FXR(h) (binding) | glyco-CDCA + FXR(h) <==> glyco-CDCA:FXR(h) (binding) | tauro-CDCA + FXR(h) <==> tauro-CDCA:FXR(h) (binding) | tauro-LCA + FXR(h) <==> tauro-LCA:FXR(h) (binding) | androsterone + FXR(h) <==> androsterone:FXR(h) (binding) | glyco-LCA + FXR(h) <==> glyco-LCA:FXR(h) (binding) | tauro-DCA + FXR(h) <==> tauro-DCA:FXR(h) (binding) | glyco-DCA + FXR(h) <==> glyco-DCA:FXR(h) (binding) | taurocholate + FXR(h) <==> taurocholate:FXR(h) (binding) | glycocholate + FXR(h) <==> glycocholate:FXR(h) (binding) | FXR(h) + SRC-1(m.s.) <==> FXR(h):SRC-1(m.s.) (binding) | FXR(h) + DRIP205(h) <==> FXR(h):DRIP205(h) (binding) | 22beta-hydroxycholesterol + FXR(h) <==> 22beta-hydroxycholesterol:FXR(h) (binding) | 3-keto-LCA + FXR(h) <==> 3-keto-LCA:FXR(h) (binding) | FXR(h) + HRMT1L2(h) <==> FXR(h):HRMT1L2(h) (binding) | FXR(h) + fatty acid-binding protein 6(h) <==> FXR(h):fatty acid-binding protein 6(h) (binding) | FXR(h) + fatty acid-binding protein 6(h) <==> FXR(h):fatty acid-binding protein 6(h) (binding) | FXR(h) + VDR(m.s.) <==> FXR(h):VDR(m.s.) (binding) | FXR(h) + T3R-beta1(m.s.) <==> FXR(h):T3R-beta1(m.s.) (binding) | FXR(h) + CARM1(m) <==> FXR(h):CARM1(m) (binding) | arachidonic acid + FXR(h) <==> arachidonic acid:FXR(h) (binding) | cervonic acid + FXR(h) <==> cervonic acid:FXR(h) (binding) | alpha-linolenic acid + FXR(h) <==> alpha-linolenic acid:FXR(h) (binding) | FXR(h) + PGC-1(m) <==> FXR(h):PGC-1(m) (binding) | FXR(h) + DRIP205(m.s.) <==> FXR(h):DRIP205(m.s.) (binding) | FXR(h) + TRC(m.s.) <==> FXR(h):TRC(m.s.) (binding) | FXR(h) + RXR-alpha(h) <==> FXR(h):RXR-alpha(h) (binding) | cafestol + FXR(h) <==> cafestol:FXR(h) (binding) | FXR(h) + GAPD(h) <==> FXR(h):GAPD(h) (binding) | FXR(h) + RXR-gamma(h) <==> FXR(h):RXR-gamma(h) (binding) | FXR(h) --> Slc2a4(m) (DNA binding; transactivation). | FXR(h) --> SLC2A4(h) (DNA binding; transactivation). | FXR(h) --> HSD3B2(h) (DNA binding; transactivation). | FXR(h) --> HHEX(h) (DNA binding). | NR1H4(h) --> FXR(h) (expression). | histone H4(h) + S-adenosylmethionine --FXR(h)--> histone H4(h){met} + S-adenosylhomocysteine (methylation) |
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Post Translational Modification [Top] | |||
There is no record for NR1H4 | |||
Methylation Profile [Top] | ||
There is no record for NR1H4 | ||