Entrez Gene

Basic Information
Gene ID	9846
Name	GAB2
Synonymous	GRB2-associated binding protein 2;GAB2;GRB2-associated binding protein 2
Definition	GRB2-associated-binding protein 2\|Grb2-associated binder 2\|growth factor receptor bound protein 2-associated protein 2\|pp100
Position	11q14.1
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Gab-2(h) + ATP --> Gab-2(h){pY} + ADP (phosphorylation)
Grb-2(m) + Gab-2(h) <==> Grb-2(m):Gab-2(h) (binding)
Gab-2(h) --> Cdc42(h) (regulation of protein activity)
GAB2(h) --> Gab-2(h) (expression).
GAB2(h) --> Gab-2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
266	Phosphotyrosine.		Swiss-Prot 53.0
405	Phosphoserine (By similarity).		Swiss-Prot 53.0
643	Phosphotyrosine	15170389	Phospho.ELM 6.0
623	Phosphoserine (MAPK3)	15356145	Phospho.ELM 6.0
324	Phosphotyrosine	16497976	Phospho.ELM 6.0
266	Phosphotyrosine	12522270	Phospho.ELM 6.0
614	Phosphotyrosine (ZAP70)	11572860	Phospho.ELM 6.0
293	Phosphotyrosine	11334882	Phospho.ELM 6.0
476	Phosphotyrosine	11334882	Phospho.ELM 6.0
584	Phosphotyrosine	11334882	Phospho.ELM 6.0
452	Phosphotyrosine	11334882	Phospho.ELM 6.0

Transcription Factors [Top]