Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

929

Name

CD14

Synonymous

CD14 molecule;CD14;CD14 molecule

Definition

monocyte differentiation antigen CD14|myeloid cell-specific leucine-rich glycoprotein

Position

5q31.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

LPS:LBP(rb) + CD14(h) <==> LPS:LBP(rb):CD14(h) (binding)
CD14(h) + TLR4(h) <==> CD14(h):TLR4(h) (binding)
PGN(STAAU) + CD14(h) <==> PGN(STAAU):CD14(h) (binding)
CD14(h) + TLR2(h) <==> CD14(h):TLR2(h) (binding)
CD14(h) --> IL-12(h) (increase of secretion)
CD14(h) --> CD14(h) (expression).
calcitriol --> CD14(h) (increase of abundance)
calcidiol --> CD14(h) (increase of abundance)
TLR2(h) + CD14(h) <==> TLR2(h):CD14(h) (binding)
CD14(h) + alpha4-integrin(h):beta1-integrin(h) <==> CD14(h):beta1-integrin(h):alpha4-integrin(h) (binding)
CD14(h) --> CD14(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

37N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
151N-linked (GlcNAc...).Swiss-Prot 53.0
282N-linked (GlcNAc...).Swiss-Prot 53.0
323N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
345GPI-anchor amidated asparagine(Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 139992694 - 139994694GSE27584

chr5

Promoter: 139992694 - 139994694Agilent_014791_44K