| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 929 |
Name | CD14 |
Synonymous | CD14 molecule;CD14;CD14 molecule |
Definition | monocyte differentiation antigen CD14|myeloid cell-specific leucine-rich glycoprotein |
Position | 5q31.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | LPS:LBP(rb) + CD14(h) <==> LPS:LBP(rb):CD14(h) (binding) | CD14(h) + TLR4(h) <==> CD14(h):TLR4(h) (binding) | PGN(STAAU) + CD14(h) <==> PGN(STAAU):CD14(h) (binding) | CD14(h) + TLR2(h) <==> CD14(h):TLR2(h) (binding) | CD14(h) --> IL-12(h) (increase of secretion) | CD14(h) --> CD14(h) (expression). | calcitriol --> CD14(h) (increase of abundance) | calcidiol --> CD14(h) (increase of abundance) | TLR2(h) + CD14(h) <==> TLR2(h):CD14(h) (binding) | CD14(h) + alpha4-integrin(h):beta1-integrin(h) <==> CD14(h):beta1-integrin(h):alpha4-integrin(h) (binding) | CD14(h) --> CD14(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 37 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 151 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 282 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 323 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 345 | GPI-anchor amidated asparagine(Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 139992694 - 139994694 | GSE27584 |
chr5 |
Promoter: 139992694 - 139994694 | Agilent_014791_44K |