| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9138 |
Name | ARHGEF1 |
Synonymous | Rho guanine nucleotide exchange factor (GEF) 1;ARHGEF1;Rho guanine nucleotide exchange factor (GEF) 1 |
Definition | 115 kDa guanine nucleotide exchange factor|115-kD protein|Lsc homolog|p115RhoGEF|rho guanine nucleotide exchange factor 1 |
Position | 19q13.13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | G-alpha-13(mo):GTP + RhoGEF(h) <==> G-alpha-13(mo):GTP:RhoGEF(h) (binding) | ARHGEF1(h) --> RhoGEF(h) (expression). | G-alpha-13(m):GTP --RhoGEF(h)--> G-alpha-13(m):GDP + p (hydrolysis) | RhoA(h):GDP + GTP --RhoGEF(h)--> RhoA(h):GTP + GDP (exchange) | G-alpha-12(m):GTP --RhoGEF(h)--> G-alpha-12(m):GDP + p (hydrolysis) | RhoGEF(h) + ATP --ATR(m.s.)--> RhoGEF(h){pS899} + ADP (phosphorylation) | ARHGEF1(h) --> RhoGEF(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for ARHGEF1 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 47077607 - 47079607 | Agilent_014791 |
chr19 |
Promoter: 47078786 - 47080786 | Agilent_014791 |
chr19 |
Promoter: 47078786 - 47080786 | GSE27584 |
chr19 |
Promoter: 47077607 - 47079607 | GSE27584 |
chr19 |
Promoter: 47077607 - 47079607 | GSE27584 |
chr19 |
Promoter: 47077607 - 47079607 | Agilent_014791_44K |